O84042 (DCD_CHLTR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	CT_039

Organism

Chlamydia trachomatis

Taxonomic identifier

813 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 190	190	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_0000155977

Sequences

	Sequence		Length	Mass (Da)
	O84042 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 7354BA4921D2071A	FASTA	190	21,414
	10 20 30 40 50 60 MGIKEDNWIR KMAIEEGMIE PFADSQVKLH PETGEKLISY GLSSYGYDLR ISREFKVFTN 70 80 90 100 110 120 VYNSLVDPKC FTEDALISIV DDVCIIPPNS FALARSVEYF RIPRNVLTVC IGKSTYARCG 130 140 150 160 170 180 LIVNVTPFEP EWEGYVTIEI SNTTPLPAKV YANEGIAQVL FFEGDATCDV SYAERQGKYQ 190 KQQGITIPFV

References

[1]

"Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis." Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L., Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W. Science 282:754-759(1998) [PubMed: 9784136] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: D/UW-3/Cx.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001273 Genomic DNA. Translation: AAC67629.1.
PIR	B71565.
RefSeq	NP_219541.1. NC_000117.1.
3D structure databases
ProteinModelPortal	O84042.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	884070.
GenomeReviews	Gene locus CT_039 in contig AE001273_GR.
KEGG	ctr:CT039.
PATRIC	20379553. VBIChlTra43535_0044.
Phylogenomic databases
HOGENOM	HBG553199.
OMA	IFRHIPG.
PhylomeDB	O84042.
ProtClustDB	PRK00416.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CHLTR

Accession

Primary (citable) accession number: O84042

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	November 1, 1998
Last modified:	January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program