Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O83990

- UDP_TREPA

UniProt

O83990 - UDP_TREPA

Protein

Uridine phosphorylase

Gene

udp

Organism
Treponema pallidum (strain Nichols)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (01 Nov 1998)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis By similarity.By similarity

    Catalytic activityi

    Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.

    Pathwayi

    GO - Molecular functioni

    1. uridine phosphorylase activity Source: UniProtKB-EC

    GO - Biological processi

    1. nucleotide catabolic process Source: InterPro
    2. UMP salvage Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciTPAL243276:GC1H-1082-MONOMER.
    UniPathwayiUPA00574; UER00633.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uridine phosphorylase (EC:2.4.2.3)
    Short name:
    UPase
    Short name:
    UrdPase
    Gene namesi
    Name:udp
    Ordered Locus Names:TP_1027
    OrganismiTreponema pallidum (strain Nichols)
    Taxonomic identifieri243276 [NCBI]
    Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
    ProteomesiUP000000811: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 258258Uridine phosphorylasePRO_0000063190Add
    BLAST

    Interactioni

    Subunit structurei

    Homohexamer.By similarity

    Protein-protein interaction databases

    STRINGi243276.TP1027.

    Structurei

    3D structure databases

    ProteinModelPortaliO83990.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PNP/UDP phosphorylase family.Curated

    Phylogenomic databases

    eggNOGiCOG2820.
    KOiK00757.
    OMAiVVANQER.
    OrthoDBiEOG676Z3T.

    Family and domain databases

    Gene3Di3.40.50.1580. 1 hit.
    InterProiIPR018017. Nucleoside_phosphorylase.
    IPR018016. Nucleoside_phosphorylase_CS.
    IPR000845. Nucleoside_phosphorylase_d.
    IPR010058. Uridine_phosphorylase.
    [Graphical view]
    PANTHERiPTHR21234. PTHR21234. 1 hit.
    PfamiPF01048. PNP_UDP_1. 1 hit.
    [Graphical view]
    SUPFAMiSSF53167. SSF53167. 1 hit.
    TIGRFAMsiTIGR01718. Uridine-psphlse. 1 hit.
    PROSITEiPS01232. PNP_UDP_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O83990-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLVYSTDCE YHIGLKASDI GHYVILPGDP ARSEKIAQHF SHPHKVGHNR    50
    EYVTYTGTLC ETPVSVMSTG IGGPSTAIGV EELIHLGAHT FIRVGTSGGM 100
    QPDILAGTVV IATGAIRFEG TSKEYAPVEF PAVPDFTVTA ALKHAAEDVQ 150
    VRHALGVVQC KDNFYGQHSP HTMPVHAELT QKWHAWIACN TLASEMESAA 200
    LFVLGSVRRV RTGAVLLVIG NQTRRAQGLE DIQVHDTENA IRVAVEAVKL 250
    LITQDSPR 258
    Length:258
    Mass (Da):27,920
    Last modified:November 1, 1998 - v1
    Checksum:i247ABA619316D72D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000520 Genomic DNA. Translation: AAC65977.1.
    PIRiF71251.
    RefSeqiNP_219464.1. NC_000919.1.
    YP_008091846.1. NC_021490.2.

    Genome annotation databases

    EnsemblBacteriaiAAC65977; AAC65977; TP_1027.
    GeneIDi15852317.
    2610897.
    KEGGitpa:TP1027.
    tpw:TPANIC_1027.
    PATRICi20532183. VBITrePal57110_1084.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000520 Genomic DNA. Translation: AAC65977.1 .
    PIRi F71251.
    RefSeqi NP_219464.1. NC_000919.1.
    YP_008091846.1. NC_021490.2.

    3D structure databases

    ProteinModelPortali O83990.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243276.TP1027.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC65977 ; AAC65977 ; TP_1027 .
    GeneIDi 15852317.
    2610897.
    KEGGi tpa:TP1027.
    tpw:TPANIC_1027.
    PATRICi 20532183. VBITrePal57110_1084.

    Phylogenomic databases

    eggNOGi COG2820.
    KOi K00757.
    OMAi VVANQER.
    OrthoDBi EOG676Z3T.

    Enzyme and pathway databases

    UniPathwayi UPA00574 ; UER00633 .
    BioCyci TPAL243276:GC1H-1082-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1580. 1 hit.
    InterProi IPR018017. Nucleoside_phosphorylase.
    IPR018016. Nucleoside_phosphorylase_CS.
    IPR000845. Nucleoside_phosphorylase_d.
    IPR010058. Uridine_phosphorylase.
    [Graphical view ]
    PANTHERi PTHR21234. PTHR21234. 1 hit.
    Pfami PF01048. PNP_UDP_1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53167. SSF53167. 1 hit.
    TIGRFAMsi TIGR01718. Uridine-psphlse. 1 hit.
    PROSITEi PS01232. PNP_UDP_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Nichols.

    Entry informationi

    Entry nameiUDP_TREPA
    AccessioniPrimary (citable) accession number: O83990
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: November 1, 1998
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3