O83970 (O83970_TREPA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA polymerase III, subunits gamma and tau (DnaH) EMBL AAC65953.1

Gene names

Ordered Locus Names:

TP_1005

Organism

Treponema pallidum (strain Nichols) [Complete proteome] [HAMAP]

Taxonomic identifier

243276 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Treponema

Protein attributes

Sequence length	572 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: InterPro
Cellular component	DNA polymerase III complex Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: InterPro nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
dnaB	O83097	2	EBI-1582351,EBI-1582320
rlmN	O83107	2	EBI-1582351,EBI-1585371

Sequences

	Sequence		Length	Mass (Da)
	O83970 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: A0A8B340FACD3B67	FASTA	572	62,486
	10 20 30 40 50 60 MAYQVTATRY RPQRFQHVLG QKFVVATLQK SLEENKVSPA YLFSGPHGCG KTSCARILAK 70 80 90 100 110 120 ALNCVQREAS EPCGECPSCR EIATGTNLNV IEIDGASHTG VGDVRQIKEE ILFPPHGTRY 130 140 150 160 170 180 KVFIIDEVHM LSNSAFNALL KTIEEPPPYV VFIFATTEVH RIPATVKSRC QQFHFRLVDT 190 200 210 220 230 240 QTLVCALAQA AQQMQIAVED GVLSWIARES AGSMRDAYTL FDQTVVSCAG PVTLENIQKK 250 260 270 280 290 300 LGLMTDDSLA ALFSHCCRKD ARAALELVDA LVSSGVSVEQ CVIDCVRYAR ALLLFTQGIT 310 320 330 340 350 360 NESLVGIAAN QVPEYVRTTW NASQIERALG LLLQLFRDIR FSVDPRYELE LAISRLAWLS 370 380 390 400 410 420 EYVSIQEVRV ALDSVQQILD THAVPGVCSA SVGSDDGETG VVSPHGIRPP MSTSVCTVRA 430 440 450 460 470 480 LQDALVEKLR ASHQMLATAL GSSYSWREED TSVCMCVRTH YERSVISQHA SLLKEYASEL 490 500 510 520 530 540 LGREVCVRVL LDSVPSSKVA PSHLPQSPAP SALFTTSLLI SGQECDRVSG DLPAQVKLLC 550 560 570 DCVQGHVVRV YEGTARCVPG EGKIAGAVRT PY

References

[1]

"Complete genome sequence of Treponema pallidum, the syphilis spirochete." Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D., Khalak H.G., Richardson D.L., Howell J.K. , Chidambaram M., Utterback T.R., McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A., Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O., Venter J.C. Science 281:375-388(1998) [PubMed: 9665876] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nichols.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000520 Genomic DNA. Translation: AAC65953.1.
PIR	G71254.
RefSeq	NP_219442.1. NC_000919.1.
3D structure databases
HSSP	HSSP built from PDB template 1NJG based on UniProtKB P06710.
ProteinModelPortal	O83970.
ModBase	Search...
Protein-protein interaction databases
IntAct	O83970. 48 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2610796.
GenomeReviews	Gene locus TP_1005 in contig AE000520_GR.
KEGG	tpa:TP1005.
NMPDR	fig|243276.1.peg.1000.
PATRIC	20532135. VBITrePal57110_1060.
TIGR	TP_1005.
Phylogenomic databases
HOGENOM	HBG732195.
OMA	ANAYIFS.
ProtClustDB	PRK06647.
Enzyme and pathway databases
BioCyc	TPAL243276:TP_1005-MONOMER.
Family and domain databases
InterPro	IPR003593. ATPase_AAA+_core. IPR003959. ATPase_AAA_core. IPR001270. Chaprnin_ClpA/B. IPR008921. DNA_pol3_clamp-load_cplx_C. IPR022754. DNA_pol_III_gamma-3. IPR012763. DNA_pol_III_sug/sutau. [Graphical view]
KO	K02343.
Pfam	PF00004. AAA. 1 hit. PF12169. DNA_pol3_gamma3. 1 hit. [Graphical view]
PRINTS	PR00300. CLPPROTEASEA.
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF48019. Pol_clamp_load_C. 1 hit.
TIGRFAMs	TIGR02397. DnaX_nterm. 1 hit.
ProtoNet	Search...

Entry information

Entry name

O83970_TREPA

Accession

Primary (citable) accession number: O83970

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	December 14, 2011
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)