O83969 (RECR_TREPA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Recombination protein RecR

Gene names

Name:	recR
Ordered Locus Names:	TP_1004

Organism

Treponema pallidum (strain Nichols) [Complete proteome] [HAMAP]

Taxonomic identifier

243276 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Spirochaetes › Spirochaetia › Spirochaetales › Spirochaetaceae › Treponema › Treponema pallidum › Treponema pallidum subsp. pallidum

Protein attributes

Sequence length	201 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO By similarity. HAMAP-Rule MF_00017
Sequence similarities	Belongs to the RecR family. Contains 1 Toprim domain.

Ontologies

Keywords
Biological process	DNA damage DNA recombination DNA repair
Domain	Zinc-finger
Ligand	Metal-binding Zinc
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA recombination Inferred from electronic annotation. Source: HAMAP DNA repair Inferred from electronic annotation. Source: HAMAP
Molecular_function	DNA binding Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 201	201	Recombination protein RecR HAMAP-Rule MF_00017		PRO_0000190416
Regions
	Domain	78 – 173	96	Toprim
	Zinc finger	55 – 70	16	C4-type Potential

Sequences

	Sequence		Length	Mass (Da)
	O83969 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 10FB4D10CED4D810	FASTA	201	21,800
	10 20 30 40 50 60 MIPAIEEVVE HLSRLPGIGV KLATRLAYHL LKRDPAEAQV LARGIACLHE RVYRCVCCGA 70 80 90 100 110 120 FCEGRTCALC TDASRDRGII CVVERAQDVE MMAGVGEYRG LFHVLGGVIA PLEGVGPDQL 130 140 150 160 170 180 RIAALLKRLQ ESSVREVILA LNPTVEGDTT ALYVQKILAN FPVIVTRLAS GIPVGGDLEY 190 200 IDRTTLAHSL RGRRPLDCSE A

References

[1]

"Complete genome sequence of Treponema pallidum, the syphilis spirochete." Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D., Khalak H.G., Richardson D.L., Howell J.K. , Chidambaram M., Utterback T.R., McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A., Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O., Venter J.C. Science 281:375-388(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nichols.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000520 Genomic DNA. Translation: AAC65952.1.
PIR	F71254.
RefSeq	NP_219441.1. NC_000919.1.
3D structure databases
ProteinModelPortal	O83969.
ModBase	Search...
Protein-protein interaction databases
IntAct	O83969. 76 interactions.
STRING	243276.TP1004.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC65952; AAC65952; TP_1004.
GeneID	2610795.
KEGG	tpa:TP1004.
PATRIC	20532133. VBITrePal57110_1059.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0353.
KO	K06187.
OMA	TDPNLEG.
ProtClustDB	PRK00076.
Family and domain databases
HAMAP	MF_00017. RecR.
InterPro	IPR000093. DNA_Rcmb_RecR. IPR023627. Rcmb_RecR. IPR023628. Rcmb_RecR_C4-type_Zn. IPR015967. Rcmb_RecR_CS. IPR006171. Toprim_domain. [Graphical view]
Pfam	PF02132. RecR. 1 hit. PF01751. Toprim. 1 hit. [Graphical view]
SMART	SM00493. TOPRIM. 1 hit. [Graphical view]
SUPFAM	SSF111304. RecR. 1 hit.
TIGRFAMs	TIGR00615. recR. 1 hit.
PROSITE	PS01300. RECR. 1 hit. PS50880. TOPRIM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RECR_TREPA

Accession

Primary (citable) accession number: O83969

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	November 1, 1998
Last modified:	May 1, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program