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Protein

Chaperone protein HtpG

Gene

htpG

Organism
Treponema pallidum (strain Nichols)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Molecular chaperone. Has ATPase activity.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTPAL243276:GC1H-1037-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein HtpGUniRule annotation
Alternative name(s):
Heat shock protein HtpGUniRule annotation
High temperature protein GUniRule annotation
Gene namesi
Name:htpGUniRule annotation
Ordered Locus Names:TP_0984
OrganismiTreponema pallidum (strain Nichols)
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
Proteomesi
  • UP000000811 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 639639Chaperone protein HtpGPRO_0000063018Add
BLAST

Proteomic databases

PRIDEiO83949.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

IntActiO83949. 10 interactions.
STRINGi243276.TP0984.

Structurei

3D structure databases

ProteinModelPortaliO83949.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 348348A; substrate-bindingUniRule annotationAdd
BLAST
Regioni349 – 565217BUniRule annotationAdd
BLAST
Regioni566 – 63974CUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the heat shock protein 90 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJX. Bacteria.
COG0326. LUCA.
KOiK04079.
OMAiYLRFMRG.

Family and domain databases

Gene3Di3.30.565.10. 1 hit.
HAMAPiMF_00505. HSP90. 1 hit.
InterProiIPR003594. HATPase_C.
IPR019805. Heat_shock_protein_90_CS.
IPR001404. Hsp90_fam.
IPR020575. Hsp90_N.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERiPTHR11528. PTHR11528. 1 hit.
PfamiPF00183. HSP90. 1 hit.
[Graphical view]
PIRSFiPIRSF002583. Hsp90. 1 hit.
PRINTSiPR00775. HEATSHOCK90.
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS00298. HSP90. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O83949-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQYEFQTEV SQLLTLIIHS LYSHKEIFLR ELISNASDAL DKLKYEALVD
60 70 80 90 100
GTYKQLHCEA RIDIAFEEDA QRLVVRDTGI GMNAEDLRAN LGTIARSGTK
110 120 130 140 150
AFLSTLTRDQ KQDSNLIGQF GVGFYSAFMV ASKVEVITKK AAENTVWKWT
160 170 180 190 200
SEGQNAYTLD EVDAAAFPVL EGVAEGSAGT CVVLHLSQEN SEFATRWRLE
210 220 230 240 250
EVIKKYSDHI AFPIYLHYLQ KEYDKDGAVT DTQKKVDQVN DAGALWKRPK
260 270 280 290 300
SELKEEDYHR FYQTLTRDST PPLLYVHTKA EGTQEYVTLF YVPAKAPFDL
310 320 330 340 350
FHADYKPGVK LFVKRVFITD DEKELLPVYL RFVRGVIDSE DLPLNVSREI
360 370 380 390 400
LQQNRVLAAI KSASVKKLLG EFKRLAECDG KKYDEFITQY NRPLKEGLYS
410 420 430 440 450
DYEHREQLLE LVRFRTLSES VPEDGWTSFA EYVSRMKPDQ KAIYYIAGND
460 470 480 490 500
DRVLRQSPHA ESYRLQGFEV LVMSDDIDGI VMPSVSKYKE WELRAINRLG
510 520 530 540 550
SEEELRPNEE TDAAAQREQG FKPLLERLTH ILSDSVKEVR LSKRLSDSVS
560 570 580 590 600
CIVIDENDPT VQMERLMRAT GQTHKSKIKP ILEINASHTL VQKLKESTDE
610 620 630
AFVEDLAFVL LDQALLIEGM DVGSSVDFVK RVNRLLARG
Length:639
Mass (Da):72,938
Last modified:November 1, 1998 - v1
Checksum:i3E8FDBAC2282C31D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000520 Genomic DNA. Translation: AAC65938.1.
PIRiF71258.
RefSeqiWP_010882428.1. NC_021490.2.

Genome annotation databases

EnsemblBacteriaiAAC65938; AAC65938; TP_0984.
GeneIDi2611612.
KEGGitpa:TP_0984.
PATRICi20532087. VBITrePal57110_1038.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000520 Genomic DNA. Translation: AAC65938.1.
PIRiF71258.
RefSeqiWP_010882428.1. NC_021490.2.

3D structure databases

ProteinModelPortaliO83949.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO83949. 10 interactions.
STRINGi243276.TP0984.

Proteomic databases

PRIDEiO83949.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC65938; AAC65938; TP_0984.
GeneIDi2611612.
KEGGitpa:TP_0984.
PATRICi20532087. VBITrePal57110_1038.

Phylogenomic databases

eggNOGiENOG4105CJX. Bacteria.
COG0326. LUCA.
KOiK04079.
OMAiYLRFMRG.

Enzyme and pathway databases

BioCyciTPAL243276:GC1H-1037-MONOMER.

Family and domain databases

Gene3Di3.30.565.10. 1 hit.
HAMAPiMF_00505. HSP90. 1 hit.
InterProiIPR003594. HATPase_C.
IPR019805. Heat_shock_protein_90_CS.
IPR001404. Hsp90_fam.
IPR020575. Hsp90_N.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERiPTHR11528. PTHR11528. 1 hit.
PfamiPF00183. HSP90. 1 hit.
[Graphical view]
PIRSFiPIRSF002583. Hsp90. 1 hit.
PRINTSiPR00775. HEATSHOCK90.
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS00298. HSP90. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHTPG_TREPA
AccessioniPrimary (citable) accession number: O83949
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1998
Last modified: September 7, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.