Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chaperone protein HtpG

Gene

htpG

Organism
Treponema pallidum (strain Nichols)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Molecular chaperone. Has ATPase activity.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein HtpGUniRule annotation
Alternative name(s):
Heat shock protein HtpGUniRule annotation
High temperature protein GUniRule annotation
Gene namesi
Name:htpGUniRule annotation
Ordered Locus Names:TP_0984
OrganismiTreponema pallidum (strain Nichols)
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
Proteomesi
  • UP000000811 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000630181 – 639Chaperone protein HtpGAdd BLAST639

Proteomic databases

PRIDEiO83949

Interactioni

Subunit structurei

Homodimer.UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

IntActiO83949, 10 interactors
STRINGi243276.TP0984

Structurei

3D structure databases

ProteinModelPortaliO83949
SMRiO83949
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 348A; substrate-bindingUniRule annotationAdd BLAST348
Regioni349 – 565BUniRule annotationAdd BLAST217
Regioni566 – 639CUniRule annotationAdd BLAST74

Sequence similaritiesi

Belongs to the heat shock protein 90 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJX Bacteria
COG0326 LUCA
KOiK04079
OMAiSDHEIFL

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
Gene3Di1.20.120.790, 1 hit
3.30.565.10, 1 hit
HAMAPiMF_00505 HSP90, 1 hit
InterProiView protein in InterPro
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
IPR019805 Heat_shock_protein_90_CS
IPR037196 HSP90_C
IPR001404 Hsp90_fam
IPR020575 Hsp90_N
IPR020568 Ribosomal_S5_D2-typ_fold
PANTHERiPTHR11528 PTHR11528, 1 hit
PfamiView protein in Pfam
PF00183 HSP90, 1 hit
PIRSFiPIRSF002583 Hsp90, 1 hit
PRINTSiPR00775 HEATSHOCK90
SMARTiView protein in SMART
SM00387 HATPase_c, 1 hit
SUPFAMiSSF110942 SSF110942, 1 hit
SSF54211 SSF54211, 1 hit
SSF55874 SSF55874, 1 hit
PROSITEiView protein in PROSITE
PS00298 HSP90, 1 hit

Sequencei

Sequence statusi: Complete.

O83949-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQYEFQTEV SQLLTLIIHS LYSHKEIFLR ELISNASDAL DKLKYEALVD
60 70 80 90 100
GTYKQLHCEA RIDIAFEEDA QRLVVRDTGI GMNAEDLRAN LGTIARSGTK
110 120 130 140 150
AFLSTLTRDQ KQDSNLIGQF GVGFYSAFMV ASKVEVITKK AAENTVWKWT
160 170 180 190 200
SEGQNAYTLD EVDAAAFPVL EGVAEGSAGT CVVLHLSQEN SEFATRWRLE
210 220 230 240 250
EVIKKYSDHI AFPIYLHYLQ KEYDKDGAVT DTQKKVDQVN DAGALWKRPK
260 270 280 290 300
SELKEEDYHR FYQTLTRDST PPLLYVHTKA EGTQEYVTLF YVPAKAPFDL
310 320 330 340 350
FHADYKPGVK LFVKRVFITD DEKELLPVYL RFVRGVIDSE DLPLNVSREI
360 370 380 390 400
LQQNRVLAAI KSASVKKLLG EFKRLAECDG KKYDEFITQY NRPLKEGLYS
410 420 430 440 450
DYEHREQLLE LVRFRTLSES VPEDGWTSFA EYVSRMKPDQ KAIYYIAGND
460 470 480 490 500
DRVLRQSPHA ESYRLQGFEV LVMSDDIDGI VMPSVSKYKE WELRAINRLG
510 520 530 540 550
SEEELRPNEE TDAAAQREQG FKPLLERLTH ILSDSVKEVR LSKRLSDSVS
560 570 580 590 600
CIVIDENDPT VQMERLMRAT GQTHKSKIKP ILEINASHTL VQKLKESTDE
610 620 630
AFVEDLAFVL LDQALLIEGM DVGSSVDFVK RVNRLLARG
Length:639
Mass (Da):72,938
Last modified:November 1, 1998 - v1
Checksum:i3E8FDBAC2282C31D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000520 Genomic DNA Translation: AAC65938.1
PIRiF71258
RefSeqiWP_010882428.1, NC_021490.2

Genome annotation databases

EnsemblBacteriaiAAC65938; AAC65938; TP_0984
GeneIDi34332300
KEGGitpa:TP_0984

Similar proteinsi

Entry informationi

Entry nameiHTPG_TREPA
AccessioniPrimary (citable) accession number: O83949
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1998
Last modified: March 28, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health