Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O83803

- SYR_TREPA

UniProt

O83803 - SYR_TREPA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Arginine--tRNA ligase

Gene

argS

Organism
Treponema pallidum (strain Nichols)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTPAL243276:GC1H-879-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:TP_0831
OrganismiTreponema pallidum (strain Nichols)
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000000811: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 589589Arginine--tRNA ligasePRO_0000151630Add
BLAST

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

IntActiO83803. 4 interactions.
STRINGi243276.TP0831.

Structurei

3D structure databases

ProteinModelPortaliO83803.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi132 – 14211"HIGH" regionAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0018.
KOiK01887.
OMAiNFERNSA.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O83803-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQDLCEMWRH AVARVLSQLQ GPAVEPVEGA QLVMEEPPEP GMGDIAFPLF
60 70 80 90 100
LFAKRVRRSP AQLAQQLCTL LEEDTSMCAY GTPQARGPYL NVFLNKECVA
110 120 130 140 150
AHTLDAIFAQ GERYGHTQYL QGKRIMVEFS SPNTNKPLHV GHLRNNAIGE
160 170 180 190 200
SLSRIIAFCG ADVFKVNIIN DRGVHICKSM CAYQKFAHGK TPAHTGIKSD
210 220 230 240 250
RFVGDWYVQF NRYAQQYPEE AEHDVRDLLQ RWESADPHVR ALWRTMNEWA
260 270 280 290 300
LRGIKQTYER TGISFDKLYF ESETYTKGRE EVRRGLACGV FYQMEDNSIW
310 320 330 340 350
VDLSSLGLDK KALLRSDGTT MYITQDIGTA IFRAQDWPFD QLLYVVGNEQ
360 370 380 390 400
NYHFKVLFFV LRLLGYPWAQ QLHHVSYGMV NLPHGRMKSR EGTVVDADDI
410 420 430 440 450
LDRLHSAAEE EIAKKGRENA LKHAQCIAEN VAIAALHYFL LQVSPQKDMV
460 470 480 490 500
FHPEESLSFN GNTGPYLQYM GARISSLLKK VQEDVEQKGP REVRCDPALL
510 520 530 540 550
THEAEWELVK ALARFPACVT RAAQGHDPSV ITGYLYTLSK SFSRFYHDCP
560 570 580
ILCEARPDYA CARLELVRAV RIVLRTAMRL VLIPFLEEM
Length:589
Mass (Da):67,132
Last modified:November 1, 1998 - v1
Checksum:iFA6156A69F4568E3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000520 Genomic DNA. Translation: AAC65797.1.
PIRiA71277.
RefSeqiNP_219267.1. NC_000919.1.
YP_008091656.1. NC_021490.2.

Genome annotation databases

EnsemblBacteriaiAAC65797; AAC65797; TP_0831.
GeneIDi15852121.
2610958.
KEGGitpa:TP0831.
tpw:TPANIC_0831.
PATRICi20531767. VBITrePal57110_0881.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000520 Genomic DNA. Translation: AAC65797.1 .
PIRi A71277.
RefSeqi NP_219267.1. NC_000919.1.
YP_008091656.1. NC_021490.2.

3D structure databases

ProteinModelPortali O83803.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi O83803. 4 interactions.
STRINGi 243276.TP0831.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC65797 ; AAC65797 ; TP_0831 .
GeneIDi 15852121.
2610958.
KEGGi tpa:TP0831.
tpw:TPANIC_0831.
PATRICi 20531767. VBITrePal57110_0881.

Phylogenomic databases

eggNOGi COG0018.
KOi K01887.
OMAi NFERNSA.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci TPAL243276:GC1H-879-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nichols.

Entry informationi

Entry nameiSYR_TREPA
AccessioniPrimary (citable) accession number: O83803
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1998
Last modified: October 29, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3