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Protein
Submitted name:

ATP-dependent Clp protease subunit A (ClpA)

Gene

clpA2

Organism
Treponema pallidum (strain Nichols)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotationSAAS annotation, Hydrolase, ProteaseImported
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent Clp protease subunit A (ClpA)Imported
Submitted name:
S14 family endopeptidase ClpAImported (EC:3.4.21.92Imported)
Gene namesi
Name:clpA2Imported
Ordered Locus Names:TP_0801Imported
ORF Names:TPANIC_0801Imported
OrganismiTreponema pallidum (strain Nichols)Imported
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
Proteomesi
  • UP000000811 Componenti: Chromosome
  • UP000014259 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi243276.TP0801

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini248 – 391AAAInterPro annotationAdd BLAST144
Domaini532 – 700AAAInterPro annotationAdd BLAST169
Domaini699 – 788ClpB_D2-smallInterPro annotationAdd BLAST90

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili301 – 321Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the ClpA/ClpB family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C2Z Bacteria
COG0542 LUCA
KOiK03694
OMAiKRMFTPE

Family and domain databases

Gene3Di1.10.1780.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR019489 Clp_ATPase_C
IPR004176 Clp_N
IPR036628 Clp_N_dom_sf
IPR013461 ClpA
IPR001270 ClpA/B
IPR018368 ClpA/B_CS1
IPR028299 ClpA/B_CS2
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00004 AAA, 1 hit
PF07724 AAA_2, 1 hit
PF02861 Clp_N, 1 hit
PF10431 ClpB_D2-small, 1 hit
PRINTSiPR00300 CLPPROTEASEA
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SM01086 ClpB_D2-small, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
SSF81923 SSF81923, 1 hit
TIGRFAMsiTIGR02639 ClpA, 1 hit
PROSITEiView protein in PROSITE
PS00870 CLPAB_1, 1 hit
PS00871 CLPAB_2, 1 hit

Sequencei

Sequence statusi: Complete.

O83779-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIIISASVQ IILDQAFDLA RKRRHEYITA EHVLFSALAH PAALEIINLC
60 70 80 90 100
SADIALIHSN LSEFLKTQVP VDLSHTPSQS LGFQHLLKRA VLYCEANKKS
110 120 130 140 150
ALEVGDLLVS LLQAETNYAS YYMRMSGMST ARLIEVIARV NGIRHGDKNV
160 170 180 190 200
SMGSNAQERY SESDDVGESA GHGPPLDGTE GDGNTADVHV HYEHCAHKRT
210 220 230 240 250
DADTHRYTVL EKYTVNLTER ARRGELAPLI GRTQEIERTI QILCRRQKNN
260 270 280 290 300
PVHVGEAGVG KTAITEGLAQ RIVRCDVPEA LEGVEIFSLD MTSLLAGTKF
310 320 330 340 350
RGDFEERLKR LAEELEKKTQ AILFIDEIHT VVGTGSGGSG GLDASNLLKP
360 370 380 390 400
LLSSGKIRCI GSTTYEEYTK HFRKDQALAR RFQKIDIEEP SEEETLRILE
410 420 430 440 450
GIRTLYEDFH AVHYSDEALA AAVRLSVQYI QGRHLPDKAI DIIDEAGACA
460 470 480 490 500
KLSRGKHGTE GVCSVIGESD IDEIVAKIAK IPKQRVSASE IEKLRNFERS
510 520 530 540 550
ISEKIFGQGE AIDLVTRTLK RARVGLRVKH KPIANLLFVG ATGVGKTELA
560 570 580 590 600
RTLAQELGIV LHRFDMSEYQ EKHTVSRLIG SPPGYVGFEE GGLLTDAVRK
610 620 630 640 650
QPHAVLLLDE IEKAHPDIFN VLLQVMDYAT LTDNQGRKAD FRNVILIMTS
660 670 680 690 700
NAGARNMGVS LIGFHKGQVG TAVIDEAVER IFSPEFRNRL DAVIRFDALS
710 720 730 740 750
LETMERIARK ELALVCEQLQ KKHIRFDITD DALALLAERS HSGGSGARNV
760 770 780 790 800
ARLVEQEVAN VLADLMLFGG VAEGDALRCT VKDRHAQCNF LRIECVQSSY

SGSIQDALG
Length:809
Mass (Da):89,328
Last modified:November 1, 1998 - v1
Checksum:iD9C8CBEE250CAEEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000520 Genomic DNA Translation: AAC65770.1
CP004010 Genomic DNA Translation: AGN75973.1
PIRiC71279
RefSeqiWP_010882246.1, NC_021490.2

Genome annotation databases

EnsemblBacteriaiAAC65770; AAC65770; TP_0801
AGN75973; AGN75973; TPANIC_0801
KEGGitpa:TP_0801
tpw:TPANIC_0801
PATRICifig|243276.9.peg.787

Similar proteinsi

Entry informationi

Entry nameiO83779_TREPA
AccessioniPrimary (citable) accession number: O83779
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: March 28, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health