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O83779

- O83779_TREPA

UniProt

O83779 - O83779_TREPA

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Protein
Submitted name:

ATP-dependent Clp protease subunit A (ClpA)

Gene

clpA2

Organism
Treponema pallidum (strain Nichols)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATP-dependent peptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

ChaperoneUniRule annotationSAAS annotation, Hydrolase, ProteaseImported

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciTPAL243276:GC1H-849-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent Clp protease subunit A (ClpA)Imported
Submitted name:
S14 family endopeptidase ClpAImported (EC:3.4.21.92Imported)
Gene namesi
Name:clpA2Imported
Ordered Locus Names:TP_0801Imported
ORF Names:TPANIC_0801Imported
OrganismiTreponema pallidum (strain Nichols)Imported
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000000811: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi243276.TP0801.

Structurei

3D structure databases

ProteinModelPortaliO83779.
SMRiO83779. Positions 208-399.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the clpA/clpB family.UniRule annotation

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

KOiK03694.
OMAiKISARTI.
OrthoDBiEOG65F8SM.

Family and domain databases

Gene3Di1.10.1780.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR019489. Clp_ATPase_C.
IPR004176. Clp_N.
IPR013461. ClpA.
IPR001270. ClpA/B.
IPR018368. ClpA/B_CS1.
IPR028299. ClpA/B_CS2.
IPR023150. Dbl_Clp-N.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11638:SF14. PTHR11638:SF14. 1 hit.
PfamiPF00004. AAA. 1 hit.
PF07724. AAA_2. 1 hit.
PF02861. Clp_N. 1 hit.
PF10431. ClpB_D2-small. 1 hit.
[Graphical view]
PRINTSiPR00300. CLPPROTEASEA.
SMARTiSM00382. AAA. 2 hits.
SM01086. ClpB_D2-small. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR02639. ClpA. 1 hit.
PROSITEiPS00870. CLPAB_1. 1 hit.
PS00871. CLPAB_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O83779 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKIIISASVQ IILDQAFDLA RKRRHEYITA EHVLFSALAH PAALEIINLC
60 70 80 90 100
SADIALIHSN LSEFLKTQVP VDLSHTPSQS LGFQHLLKRA VLYCEANKKS
110 120 130 140 150
ALEVGDLLVS LLQAETNYAS YYMRMSGMST ARLIEVIARV NGIRHGDKNV
160 170 180 190 200
SMGSNAQERY SESDDVGESA GHGPPLDGTE GDGNTADVHV HYEHCAHKRT
210 220 230 240 250
DADTHRYTVL EKYTVNLTER ARRGELAPLI GRTQEIERTI QILCRRQKNN
260 270 280 290 300
PVHVGEAGVG KTAITEGLAQ RIVRCDVPEA LEGVEIFSLD MTSLLAGTKF
310 320 330 340 350
RGDFEERLKR LAEELEKKTQ AILFIDEIHT VVGTGSGGSG GLDASNLLKP
360 370 380 390 400
LLSSGKIRCI GSTTYEEYTK HFRKDQALAR RFQKIDIEEP SEEETLRILE
410 420 430 440 450
GIRTLYEDFH AVHYSDEALA AAVRLSVQYI QGRHLPDKAI DIIDEAGACA
460 470 480 490 500
KLSRGKHGTE GVCSVIGESD IDEIVAKIAK IPKQRVSASE IEKLRNFERS
510 520 530 540 550
ISEKIFGQGE AIDLVTRTLK RARVGLRVKH KPIANLLFVG ATGVGKTELA
560 570 580 590 600
RTLAQELGIV LHRFDMSEYQ EKHTVSRLIG SPPGYVGFEE GGLLTDAVRK
610 620 630 640 650
QPHAVLLLDE IEKAHPDIFN VLLQVMDYAT LTDNQGRKAD FRNVILIMTS
660 670 680 690 700
NAGARNMGVS LIGFHKGQVG TAVIDEAVER IFSPEFRNRL DAVIRFDALS
710 720 730 740 750
LETMERIARK ELALVCEQLQ KKHIRFDITD DALALLAERS HSGGSGARNV
760 770 780 790 800
ARLVEQEVAN VLADLMLFGG VAEGDALRCT VKDRHAQCNF LRIECVQSSY

SGSIQDALG
Length:809
Mass (Da):89,328
Last modified:November 1, 1998 - v1
Checksum:iD9C8CBEE250CAEEE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000520 Genomic DNA. Translation: AAC65770.1.
CP004010 Genomic DNA. Translation: AGN75973.1.
PIRiC71279.
RefSeqiNP_219238.1. NC_000919.1.
YP_008091628.1. NC_021490.2.

Genome annotation databases

EnsemblBacteriaiAAC65770; AAC65770; TP_0801.
AGN75973; AGN75973; TPANIC_0801.
GeneIDi15852092.
2610835.
KEGGitpa:TP0801.
tpw:TPANIC_0801.
PATRICi20531697. VBITrePal57110_0846.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000520 Genomic DNA. Translation: AAC65770.1 .
CP004010 Genomic DNA. Translation: AGN75973.1 .
PIRi C71279.
RefSeqi NP_219238.1. NC_000919.1.
YP_008091628.1. NC_021490.2.

3D structure databases

ProteinModelPortali O83779.
SMRi O83779. Positions 208-399.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243276.TP0801.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC65770 ; AAC65770 ; TP_0801 .
AGN75973 ; AGN75973 ; TPANIC_0801 .
GeneIDi 15852092.
2610835.
KEGGi tpa:TP0801.
tpw:TPANIC_0801.
PATRICi 20531697. VBITrePal57110_0846.

Phylogenomic databases

KOi K03694.
OMAi KISARTI.
OrthoDBi EOG65F8SM.

Enzyme and pathway databases

BioCyci TPAL243276:GC1H-849-MONOMER.

Family and domain databases

Gene3Di 1.10.1780.10. 1 hit.
3.40.50.300. 2 hits.
InterProi IPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR019489. Clp_ATPase_C.
IPR004176. Clp_N.
IPR013461. ClpA.
IPR001270. ClpA/B.
IPR018368. ClpA/B_CS1.
IPR028299. ClpA/B_CS2.
IPR023150. Dbl_Clp-N.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR11638:SF14. PTHR11638:SF14. 1 hit.
Pfami PF00004. AAA. 1 hit.
PF07724. AAA_2. 1 hit.
PF02861. Clp_N. 1 hit.
PF10431. ClpB_D2-small. 1 hit.
[Graphical view ]
PRINTSi PR00300. CLPPROTEASEA.
SMARTi SM00382. AAA. 2 hits.
SM01086. ClpB_D2-small. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 2 hits.
TIGRFAMsi TIGR02639. ClpA. 1 hit.
PROSITEi PS00870. CLPAB_1. 1 hit.
PS00871. CLPAB_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NicholsImported.
  2. "Resequencing of Treponema pallidum ssp. pallidum strains Nichols and SS14: Correction of sequencing errors resulted in increased separation of syphilis treponeme subclusters."
    Petrosova H., Pospisilova P., Strouhal M., Cejkova D., Zobanikova M., Mikalova L., Sodergren E., Weinstock G.M., Smajs D.
    PLoS ONE 8:E74319-E74319(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NicholsImported.

Entry informationi

Entry nameiO83779_TREPA
AccessioniPrimary (citable) accession number: O83779
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: October 29, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3