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O83779

- O83779_TREPA

UniProt

O83779 - O83779_TREPA

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Protein
Submitted name: ATP-dependent Clp protease subunit A (ClpA)
Gene
clpA2, TP_0801, TPANIC_0801
Organism
Treponema pallidum (strain Nichols)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATP-dependent peptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

ChaperoneUniRule annotationSAAS annotations, Hydrolase, ProteaseImported

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciTPAL243276:GC1H-849-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent Clp protease subunit A (ClpA)Imported
Submitted name:
S14 family endopeptidase ClpAImported (EC:3.4.21.92Imported)
Gene namesi
Name:clpA2Imported
Ordered Locus Names:TP_0801Imported
ORF Names:TPANIC_0801Imported
OrganismiTreponema pallidum (strain Nichols)Imported
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000000811: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi243276.TP0801.

Family & Domainsi

Sequence similaritiesi

Belongs to the clpA/clpB family.UniRule annotation

Keywords - Domaini

RepeatSAAS annotations

Phylogenomic databases

KOiK03694.
OMAiKISARTI.
OrthoDBiEOG65F8SM.

Family and domain databases

Gene3Di1.10.1780.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR019489. Clp_ATPase_C.
IPR004176. Clp_N.
IPR013461. ClpA.
IPR001270. ClpA/B.
IPR018368. ClpA/B_CS1.
IPR028299. ClpA/B_CS2.
IPR023150. Dbl_Clp-N.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11638:SF14. PTHR11638:SF14. 1 hit.
PfamiPF00004. AAA. 1 hit.
PF07724. AAA_2. 1 hit.
PF02861. Clp_N. 1 hit.
PF10431. ClpB_D2-small. 1 hit.
[Graphical view]
PRINTSiPR00300. CLPPROTEASEA.
SMARTiSM00382. AAA. 2 hits.
SM01086. ClpB_D2-small. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR02639. ClpA. 1 hit.
PROSITEiPS00870. CLPAB_1. 1 hit.
PS00871. CLPAB_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O83779-1 [UniParc]FASTAAdd to Basket

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MKIIISASVQ IILDQAFDLA RKRRHEYITA EHVLFSALAH PAALEIINLC    50
SADIALIHSN LSEFLKTQVP VDLSHTPSQS LGFQHLLKRA VLYCEANKKS 100
ALEVGDLLVS LLQAETNYAS YYMRMSGMST ARLIEVIARV NGIRHGDKNV 150
SMGSNAQERY SESDDVGESA GHGPPLDGTE GDGNTADVHV HYEHCAHKRT 200
DADTHRYTVL EKYTVNLTER ARRGELAPLI GRTQEIERTI QILCRRQKNN 250
PVHVGEAGVG KTAITEGLAQ RIVRCDVPEA LEGVEIFSLD MTSLLAGTKF 300
RGDFEERLKR LAEELEKKTQ AILFIDEIHT VVGTGSGGSG GLDASNLLKP 350
LLSSGKIRCI GSTTYEEYTK HFRKDQALAR RFQKIDIEEP SEEETLRILE 400
GIRTLYEDFH AVHYSDEALA AAVRLSVQYI QGRHLPDKAI DIIDEAGACA 450
KLSRGKHGTE GVCSVIGESD IDEIVAKIAK IPKQRVSASE IEKLRNFERS 500
ISEKIFGQGE AIDLVTRTLK RARVGLRVKH KPIANLLFVG ATGVGKTELA 550
RTLAQELGIV LHRFDMSEYQ EKHTVSRLIG SPPGYVGFEE GGLLTDAVRK 600
QPHAVLLLDE IEKAHPDIFN VLLQVMDYAT LTDNQGRKAD FRNVILIMTS 650
NAGARNMGVS LIGFHKGQVG TAVIDEAVER IFSPEFRNRL DAVIRFDALS 700
LETMERIARK ELALVCEQLQ KKHIRFDITD DALALLAERS HSGGSGARNV 750
ARLVEQEVAN VLADLMLFGG VAEGDALRCT VKDRHAQCNF LRIECVQSSY 800
SGSIQDALG 809
Length:809
Mass (Da):89,328
Last modified:November 1, 1998 - v1
Checksum:iD9C8CBEE250CAEEE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000520 Genomic DNA. Translation: AAC65770.1.
CP004010 Genomic DNA. Translation: AGN75973.1.
PIRiC71279.
RefSeqiNP_219238.1. NC_000919.1.
YP_008091628.1. NC_021490.2.

Genome annotation databases

EnsemblBacteriaiAAC65770; AAC65770; TP_0801.
AGN75973; AGN75973; TPANIC_0801.
GeneIDi15852092.
2610835.
KEGGitpa:TP0801.
tpw:TPANIC_0801.
PATRICi20531697. VBITrePal57110_0846.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000520 Genomic DNA. Translation: AAC65770.1 .
CP004010 Genomic DNA. Translation: AGN75973.1 .
PIRi C71279.
RefSeqi NP_219238.1. NC_000919.1.
YP_008091628.1. NC_021490.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243276.TP0801.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC65770 ; AAC65770 ; TP_0801 .
AGN75973 ; AGN75973 ; TPANIC_0801 .
GeneIDi 15852092.
2610835.
KEGGi tpa:TP0801.
tpw:TPANIC_0801.
PATRICi 20531697. VBITrePal57110_0846.

Phylogenomic databases

KOi K03694.
OMAi KISARTI.
OrthoDBi EOG65F8SM.

Enzyme and pathway databases

BioCyci TPAL243276:GC1H-849-MONOMER.

Family and domain databases

Gene3Di 1.10.1780.10. 1 hit.
3.40.50.300. 2 hits.
InterProi IPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR019489. Clp_ATPase_C.
IPR004176. Clp_N.
IPR013461. ClpA.
IPR001270. ClpA/B.
IPR018368. ClpA/B_CS1.
IPR028299. ClpA/B_CS2.
IPR023150. Dbl_Clp-N.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR11638:SF14. PTHR11638:SF14. 1 hit.
Pfami PF00004. AAA. 1 hit.
PF07724. AAA_2. 1 hit.
PF02861. Clp_N. 1 hit.
PF10431. ClpB_D2-small. 1 hit.
[Graphical view ]
PRINTSi PR00300. CLPPROTEASEA.
SMARTi SM00382. AAA. 2 hits.
SM01086. ClpB_D2-small. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 2 hits.
TIGRFAMsi TIGR02639. ClpA. 1 hit.
PROSITEi PS00870. CLPAB_1. 1 hit.
PS00871. CLPAB_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NicholsImported.
  2. "Resequencing of Treponema pallidum ssp. pallidum strains Nichols and SS14: Correction of sequencing errors resulted in increased separation of syphilis treponeme subclusters."
    Petrosova H., Pospisilova P., Strouhal M., Cejkova D., Zobanikova M., Mikalova L., Sodergren E., Weinstock G.M., Smajs D.
    PLoS ONE 8:E74319-E74319(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NicholsImported.

Entry informationi

Entry nameiO83779_TREPA
AccessioniPrimary (citable) accession number: O83779
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: July 9, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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