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Protein

Flagellar biosynthetic protein FlhB

Gene

flhB

Organism
Treponema pallidum (strain Nichols)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Bacterial flagellum biogenesis, Bacterial flagellum protein export, Protein transport, Transport

Enzyme and pathway databases

BioCyciTPAL243276:GC1H-761-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar biosynthetic protein FlhB
Gene namesi
Name:flhB
Ordered Locus Names:TP_0715
OrganismiTreponema pallidum (strain Nichols)
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
Proteomesi
  • UP000000811 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei51 – 7121HelicalSequence analysisAdd
BLAST
Transmembranei97 – 11721HelicalSequence analysisAdd
BLAST
Transmembranei161 – 18121HelicalSequence analysisAdd
BLAST
Transmembranei202 – 22221HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 376376Flagellar biosynthetic protein FlhBPRO_0000180954Add
BLAST

Interactioni

Protein-protein interaction databases

IntActiO83710. 2 interactions.
MINTiMINT-6480134.
STRINGi243276.TP0715.

Structurei

3D structure databases

ProteinModelPortaliO83710.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the type III secretion exporter family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105D00. Bacteria.
COG1377. LUCA.
KOiK02401.
OMAiKMMQEIP.
OrthoDBiEOG6FRD1F.

Family and domain databases

Gene3Di3.40.1690.10. 1 hit.
InterProiIPR006136. FlhB.
IPR006135. T3SS_substrate_exporter.
IPR029025. T3SS_substrate_exporter_C.
[Graphical view]
PANTHERiPTHR30531. PTHR30531. 1 hit.
PfamiPF01312. Bac_export_2. 1 hit.
[Graphical view]
PRINTSiPR00950. TYPE3IMSPROT.
SUPFAMiSSF160544. SSF160544. 1 hit.
TIGRFAMsiTIGR00328. flhB. 1 hit.

Sequencei

Sequence statusi: Complete.

O83710-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEQEGTFPL PLFIIDLQWF AAEDEGRSED PTETKLRKAR EEGRVPKSQD
60 70 80 90 100
LNGAFVMLFT STSLFLLAPF ILRECIGVLR FFFTRATTAS IQNTGWFFVF
110 120 130 140 150
VRYFMKLALP ISFVALVSGV AANIVQNKTV LFSVKSIRPQ FKKISPDVIR
160 170 180 190 200
FFKRSFFSTE GLFNLLKSLI KITAIFFVSY FTIRNDLFMF VSLLGVSLTQ
210 220 230 240 250
SIFYITSLAG KVLLEVSLLL VVFSLPDYFF QRRQFIDSLK MSRQEVKEEL
260 270 280 290 300
KEQEGDPLVR SYVRKQMQSL VRESARNTTD ADVVITNPTH FAVAVQYEPA
310 320 330 340 350
YMTAPTVVAK GSDGTAYRIK RLAKEAGILI EENKPLARAL YTQVAIGREV
360 370
PYEYFNALVL IFTKLDKFKT HAQRKR
Length:376
Mass (Da):43,039
Last modified:November 1, 1998 - v1
Checksum:iFEA32E2E8B269540
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti357 – 37620ALVLI…AQRKR → CFSADFYQAG in AAB00549 (PubMed:8529894).CuratedAdd
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U36839 Genomic DNA. Translation: AAB00549.1.
AE000520 Genomic DNA. Translation: AAC65681.1.
PIRiG71290.
RefSeqiWP_010882160.1. NC_021490.2.

Genome annotation databases

EnsemblBacteriaiAAC65681; AAC65681; TP_0715.
GeneIDi2610989.
KEGGitpa:TP_0715.
PATRICi20531521. VBITrePal57110_0760.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U36839 Genomic DNA. Translation: AAB00549.1.
AE000520 Genomic DNA. Translation: AAC65681.1.
PIRiG71290.
RefSeqiWP_010882160.1. NC_021490.2.

3D structure databases

ProteinModelPortaliO83710.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO83710. 2 interactions.
MINTiMINT-6480134.
STRINGi243276.TP0715.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC65681; AAC65681; TP_0715.
GeneIDi2610989.
KEGGitpa:TP_0715.
PATRICi20531521. VBITrePal57110_0760.

Phylogenomic databases

eggNOGiENOG4105D00. Bacteria.
COG1377. LUCA.
KOiK02401.
OMAiKMMQEIP.
OrthoDBiEOG6FRD1F.

Enzyme and pathway databases

BioCyciTPAL243276:GC1H-761-MONOMER.

Family and domain databases

Gene3Di3.40.1690.10. 1 hit.
InterProiIPR006136. FlhB.
IPR006135. T3SS_substrate_exporter.
IPR029025. T3SS_substrate_exporter_C.
[Graphical view]
PANTHERiPTHR30531. PTHR30531. 1 hit.
PfamiPF01312. Bac_export_2. 1 hit.
[Graphical view]
PRINTSiPR00950. TYPE3IMSPROT.
SUPFAMiSSF160544. SSF160544. 1 hit.
TIGRFAMsiTIGR00328. flhB. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification and sequences of the Treponema pallidum fliM', fliY, fliP, fliQ, fliR and flhB' genes."
    Hardham J.M., Frye J.G., Stamm L.V.
    Gene 166:57-64(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Nichols.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nichols.

Entry informationi

Entry nameiFLHB_TREPA
AccessioniPrimary (citable) accession number: O83710
Secondary accession number(s): Q56337
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1998
Last modified: July 6, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.