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O83541 (VATA2_TREPA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
V-type ATP synthase alpha chain 2
EC=3.6.3.14
Alternative name(s):
V-ATPase subunit A 2
Gene names
Name:atpA2
Ordered Locus Names:TP_0529
OrganismTreponema pallidum (strain Nichols) [Complete proteome] [HAMAP]
Taxonomic identifier243276 [NCBI]
Taxonomic lineageBacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Treponema

Protein attributes

Sequence length605 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. HAMAP MF_00309

Catalytic activity

ATP + H2O + H+(In) = ADP + phosphate + H+(Out). HAMAP MF_00309

Sequence similarities

Belongs to the ATPase alpha/beta chains family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 605605V-type ATP synthase alpha chain 2 HAMAP MF_00309
PRO_0000144621

Regions

Nucleotide binding242 – 2498ATP Potential

Sequences

Sequence LengthMass (Da)Tools
O83541 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 65A2CB82B3822EE6

FASTA60566,740
        10         20         30         40         50         60 
MIKDDVVTGR VVRVSGPIVY AEGLSACSVY DVVDVGEASL IGEIIRLDES KAVVQVYEDD 

        70         80         90        100        110        120 
TGMRVGEKVT SLRRPLSVRL GPGLIGTIYD GIQRPLERLF QEDGAFLRPG ARSQPLDGSV 

       130        140        150        160        170        180 
RWDFRPHCNE RGEALCAGIP IAPGSVLGTV QETPSVVHTI MVPPDIRGSV LSSFKGAGAY 

       190        200        210        220        230        240 
TIDEEIGRTD LGEPLFLSQY WPVRRARPFS KKLAVCEPLV TGQRAIDVFF PLSKGGTAAI 

       250        260        270        280        290        300 
PGGFGTGKTM TQHAVAKWCD ADIIVYIGCG ERGNEMTDVL SEFPKLIDPR TGRSLMERTI 

       310        320        330        340        350        360 
LIANTSNMPV SAREVSLYSG ITLAEYYRDM GMHVAIMADS TSRWAEALRE LSGRMEEMPA 

       370        380        390        400        410        420 
EEGFPAYLPT RLAEFYERAG RVETCVAREG SVSIIGAVSP LGGDFSEPVT QHTKRFIRCF 

       430        440        450        460        470        480 
WALDRELAHA RHYPAIGWID SYSEYAQEVS AWWSKYDPRA GALRAAALDL LRKEQRLQQI 

       490        500        510        520        530        540 
VRLVGPDALP GEDRLVLMVC EMIKGGFLQQ NAFDPTDVFS CPEKQVQILR TIVDFHERAV 

       550        560        570        580        590        600 
VLLRAGISLS ALSQLSCREL IVRMKTTYGN EDVHKMQKVY DTMCTEFDQL SVCAAARTQG 


GEKVE

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000520 Genomic DNA. Translation: AAC65516.1.
PIRC71313.
RefSeqNP_218969.1. NC_000919.1.

3D structure databases

ProteinModelPortalO83541.
SMRO83541. Positions 64-590.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2610788.
GenomeReviewsGene locus TP_0529 in contig AE000520_GR.
KEGGtpa:TP0529.
NMPDRfig|243276.1.peg.528.
PATRIC20531099. VBITrePal57110_0564.
TIGRTP_0529.

Phylogenomic databases

HOGENOMHBG288114.
OMATIDEEIG.
ProtClustDBPRK04192.

Enzyme and pathway databases

BioCycTPAL243276:TP_0529-MONOMER.

Family and domain databases

HAMAPMF_00309. ATP_synth_A_arch.
[Tree]
InterProIPR018118. ATPase_F1/A1-cplx_a/bsu_N.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR004100. ATPase_F1/V1/A1-cplx_a/bsu_N.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR024034. ATPase_F1_bsu/V1_C.
IPR022878. V-ATPase_su_A/alpha.
[Graphical view]
Gene3DG3DSA:1.10.1140.10. G3DSA:1.10.1140.10. 1 hit.
KOK02117.
PfamPF00006. ATP-synt_ab. 1 hit.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
SUPFAMSSF47917. ATPase_a/b_C. 1 hit.
SSF50615. ATPase_a/b_N. 1 hit.
PROSITEPS00152. ATPASE_ALPHA_BETA. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameVATA2_TREPA
AccessionPrimary (citable) accession number: O83541
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: November 1, 1998
Last modified: January 25, 2012
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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