O83540 (VATB2_TREPA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
V-type ATP synthase beta chain 2

Alternative name(s):
V-ATPase subunit B 2

Gene names

Name:	atpB2
Ordered Locus Names:	TP_0528

Organism

Treponema pallidum (strain Nichols) [Complete proteome] [HAMAP]

Taxonomic identifier

243276 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Treponema

Protein attributes

Sequence length	480 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. HAMAP MF_00310
Sequence similarities	Belongs to the ATPase alpha/beta chains family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ATP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	proton-transporting two-sector ATPase complex, catalytic domain Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 480	480	V-type ATP synthase beta chain 2 HAMAP MF_00310		PRO_0000144684

Sequences

	Sequence		Length	Mass (Da)
	O83540 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: D02C999311D3EF92	FASTA	480	53,057
	10 20 30 40 50 60 MKGVWYRGLS SIDGPIVVAK RREGAFYGEI TAIRDRFGAL RTGRIIDLSQ ECCLIQVFGS 70 80 90 100 110 120 TLGLSLDGAC LEFLDVPMQL RVCEGLMGRV FDGLGRPIDG FPEVLSSQLR NVNGYPINPY 130 140 150 160 170 180 ARVYPRDFIQ TGISAIDGMN TLIRGQKLPI FSGNGLAHNR LAAQIIRQAK ILGTDEAFVM 190 200 210 220 230 240 VFAGMGIKHD VARFFVSSFE ETGVLSKVVM FLSLADAPSI ERIITPRCAL TAAEYLAFEK 250 260 270 280 290 300 NKHVLVIFTD MTNYCEALRE VSTTRGEVPG RKGYPGYLYS DLAELYERAG RVKGSSGSVT 310 320 330 340 350 360 QIPILTMPND DISHPIPDLT GYITEGQIVL QRDLSQRGLY PPIGCLPSLS RLMKDGIGEG 370 380 390 400 410 420 MTRADHHAVS SQLFASYARV QSVRSLASIV GEEELPALDK CYLRFGDLFE QYFLTQDEHE 430 440 450 460 470 480 DRSISQTLDI GWSLLSLLPR TELYRIDPKL IDQYLTASCS AVSDQLRKAI EEARTPVADA

References

[1]

"Complete genome sequence of Treponema pallidum, the syphilis spirochete." Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D., Khalak H.G., Richardson D.L., Howell J.K. , Chidambaram M., Utterback T.R., McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A., Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O., Venter J.C. Science 281:375-388(1998) [PubMed: 9665876] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nichols.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000520 Genomic DNA. Translation: AAC65515.1.
PIR	B71313.
RefSeq	NP_218968.1. NC_000919.1.
3D structure databases
ProteinModelPortal	O83540.
SMR	O83540. Positions 14-457.
ModBase	Search...
Protein-protein interaction databases
IntAct	O83540. 7 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2610778.
GenomeReviews	Gene locus TP_0528 in contig AE000520_GR.
KEGG	tpa:TP0528.
NMPDR	fig|243276.1.peg.527.
PATRIC	20531097. VBITrePal57110_0563.
TIGR	TP_0528.
Phylogenomic databases
HOGENOM	HBG565875.
OMA	DGIGEGY.
ProtClustDB	PRK04196.
Enzyme and pathway databases
BioCyc	TPAL243276:TP_0528-MONOMER.
Family and domain databases
HAMAP	MF_00310. ATP_synth_B_arch. [Tree]
InterPro	IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C. IPR004100. ATPase_F1/V1/A1-cplx_a/bsu_N. IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd. IPR022879. V-ATPase_su_B/beta. [Graphical view]
KO	K02118.
Pfam	PF00006. ATP-synt_ab. 1 hit. PF00306. ATP-synt_ab_C. 1 hit. PF02874. ATP-synt_ab_N. 1 hit. [Graphical view]
PROSITE	PS00152. ATPASE_ALPHA_BETA. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

VATB2_TREPA

Accession

Primary (citable) accession number: O83540

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2001
Last sequence update:	November 1, 1998
Last modified:	January 25, 2012
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program