O83539 (VATD2_TREPA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
V-type ATP synthase subunit D 2

Alternative name(s):
V-ATPase subunit D 2

Gene names

Name:	atpD2
Ordered Locus Names:	TP_0527

Organism

Treponema pallidum (strain Nichols) [Complete proteome] [HAMAP]

Taxonomic identifier

243276 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Treponema

Protein attributes

Sequence length	209 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. HAMAP MF_00271
Sequence similarities	Belongs to the V-ATPase D subunit family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ATP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	proton-transporting two-sector ATPase complex, catalytic domain Inferred from electronic annotation. Source: InterPro
Molecular function	proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 209	209	V-type ATP synthase subunit D 2 HAMAP MF_00271		PRO_0000144274

Sequences

	Sequence		Length	Mass (Da)
	O83539 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 0647A0E11B7DE62B	FASTA	209	23,926
	10 20 30 40 50 60 MKTPLAPTKS NLAYVRDQLG LARDGYRLLE QKREILFMEL TSLLEEVHLL ETELDKRRKQ 70 80 90 100 110 120 AYASLWQLLL AQGRDDIAAC ALVTPVPCRV QQEVLLIAGL RFLRLDAVMQ PPKLQYAALG 130 140 150 160 170 180 SSACMDRARE DFGLLLQTLT RMASVQTIVW RLASEMRKTQ RRVNALSKQI IPQMCETCMY 190 200 IESVLEERDR ESTFVLKSLK ARKDPTTTL

References

[1]

"Complete genome sequence of Treponema pallidum, the syphilis spirochete." Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D., Khalak H.G., Richardson D.L., Howell J.K. , Chidambaram M., Utterback T.R., McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A., Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O., Venter J.C. Science 281:375-388(1998) [PubMed: 9665876] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nichols.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000520 Genomic DNA. Translation: AAC65514.1.
PIR	A71313.
RefSeq	NP_218967.1. NC_000919.1.
3D structure databases
ProteinModelPortal	O83539.
ModBase	Search...
Protein-protein interaction databases
IntAct	O83539. 18 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2610777.
GenomeReviews	Gene locus TP_0527 in contig AE000520_GR.
KEGG	tpa:TP0527.
NMPDR	fig|243276.1.peg.526.
PATRIC	20531095. VBITrePal57110_0562.
TIGR	TP_0527.
Phylogenomic databases
HOGENOM	HBG732046.
OMA	TQKRANA.
ProtClustDB	CLSK2300235.
Enzyme and pathway databases
BioCyc	TPAL243276:TP_0527-MONOMER.
Family and domain databases
HAMAP	MF_00271. ATP_synth_D_arch. [Tree]
InterPro	IPR002699. ATPase_V1/A1-cplx_dsu. [Graphical view]
KO	K02120.
Pfam	PF01813. ATP-synt_D. 1 hit. [Graphical view]
TIGRFAMs	TIGR00309. V_ATPase_subD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

VATD2_TREPA

Accession

Primary (citable) accession number: O83539

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2001
Last sequence update:	November 1, 1998
Last modified:	January 25, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program