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O83518 (O83518_TREPA) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
EC=2.7.1.1 EMBL AGN75694.1

Hexokinase (Hxk) EMBL AAC65489.1
Gene names
Ordered Locus Names:TP_0505 EMBL AAC65489.1
ORF Names:TPANIC_0505 EMBL AGN75694.1
OrganismTreponema pallidum (strain Nichols) [Complete proteome] [HAMAP] EMBL AAC65489.1
Taxonomic identifier243276 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema

Protein attributes

Sequence length444 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the hexokinase family. RuleBase RU004510

Ontologies

Keywords
   Molecular functionKinase EMBL AAC65489.1
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionATP binding

Inferred from electronic annotation. Source: InterPro

hexokinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
O83518 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 5ACC3E1100D4B07E

FASTA44447,845
        10         20         30         40         50         60 
MDQHTRTRDL VSAFFGRFHF DVQGPSVRTV VDVLRADMVR GLEEEAQLPP RMGSALAMIP 

        70         80         90        100        110        120 
TWVAPPRVSP CNRRVIVIDA GGTNFRSCLV RFGDSGTPHI ENLEKRPMPG TTREYSRTEF 

       130        140        150        160        170        180 
FGEIADNLAR LKGAADCIGF CFSYPIRIRP DGDGEVIQFA KEIKAAEVIG TCVGAGLTEA 

       190        200        210        220        230        240 
LSARNWPELR SLKMLNDATS ALLAGFFAAP EGCSFSSYVG FILGTGMNSA YLEPDPIPKI 

       250        260        270        280        290        300 
PAHHTPQVVV CESGKSNKVP RSVFDELFTQ TTAEPDIAHL EKMSSGTYLG PLASVVVRLA 

       310        320        330        340        350        360 
AQEGLFSHAV HAALSTVSFT LVDMDRFLFA PSVSTTTLGA LLAPGTDTDR EILFLLLDAV 

       370        380        390        400        410        420 
VARAARIAAG VIAASVLKSG AGYDPLRPVC VLAEGTTFQR TYRLRTRVTS HLQAFLTEER 

       430        440 
GVYFDIISLE NAVTLGSALG GLSS 

« Hide

References

[1]"Complete genome sequence of Treponema pallidum, the syphilis spirochete."
Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R., Gwinn M., Hickey E.K., Clayton R., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S., Peterson J., Khalak H., Richardson D., Howell J.K. expand/collapse author list , Chidambaram M., Utterback T., McDonald L., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S., Hatch B., Horst K., Roberts K., Watthey L., Weidman J., Smith H.O., Venter J.C.
Science 281:375-388(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Nichols EMBL AAC65489.1.
[2]"Resequencing of Treponema pallidum ssp. pallidum Strains Nichols and SS14: Correction of Sequencing Errors Resulted in Increased Separation of Syphilis Treponeme Subclusters."
Petrosova H., Pospisilova P., Strouhal M., Cejkova D., Zobanikova M., Mikalova L., Sodergren E., Weinstock G.M., Smajs D.
PLoS ONE 8:E74319-E74319(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Nichols EMBL AGN75694.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000520 Genomic DNA. Translation: AAC65489.1.
CP004010 Genomic DNA. Translation: AGN75694.1.
PIRE71317.
RefSeqNP_218946.1. NC_000919.1.
YP_008091349.1. NC_021490.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243276.TP0505.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC65489; AAC65489; TP_0505.
GeneID15851791.
2611669.
KEGGtpa:TP0505.
tpw:TPANIC_0505.
PATRIC20531041. VBITrePal57110_0538.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00844.
OMASSNANDM.
OrthoDBEOG6TJ7TW.
ProtClustDBCLSK913581.

Enzyme and pathway databases

BioCycTPAL243276:GC1H-534-MONOMER.

Family and domain databases

InterProIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERPTHR19443. PTHR19443. 1 hit.
PfamPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSPR00475. HEXOKINASE.
ProtoNetSearch...

Entry information

Entry nameO83518_TREPA
AccessionPrimary (citable) accession number: O83518
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: April 16, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)