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O83518

- O83518_TREPA

UniProt

O83518 - O83518_TREPA

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Protein
Submitted name:

Hexokinase

Gene

TP_0505

Organism
Treponema pallidum (strain Nichols)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. hexokinase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Enzyme and pathway databases

BioCyciTPAL243276:GC1H-534-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
HexokinaseImported (EC:2.7.1.1Imported)
Submitted name:
Hexokinase (Hxk)Imported
Gene namesi
Ordered Locus Names:TP_0505Imported
ORF Names:TPANIC_0505Imported
OrganismiTreponema pallidum (strain Nichols)Imported
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000000811: Chromosome

Interactioni

Protein-protein interaction databases

IntActiO83518. 2 interactions.
STRINGi243276.TP0505.

Structurei

3D structure databases

ProteinModelPortaliO83518.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

KOiK00844.
OMAiGRYMDND.
OrthoDBiEOG6TJ7TW.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.

Sequencei

Sequence statusi: Complete.

O83518 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MDQHTRTRDL VSAFFGRFHF DVQGPSVRTV VDVLRADMVR GLEEEAQLPP
60 70 80 90 100
RMGSALAMIP TWVAPPRVSP CNRRVIVIDA GGTNFRSCLV RFGDSGTPHI
110 120 130 140 150
ENLEKRPMPG TTREYSRTEF FGEIADNLAR LKGAADCIGF CFSYPIRIRP
160 170 180 190 200
DGDGEVIQFA KEIKAAEVIG TCVGAGLTEA LSARNWPELR SLKMLNDATS
210 220 230 240 250
ALLAGFFAAP EGCSFSSYVG FILGTGMNSA YLEPDPIPKI PAHHTPQVVV
260 270 280 290 300
CESGKSNKVP RSVFDELFTQ TTAEPDIAHL EKMSSGTYLG PLASVVVRLA
310 320 330 340 350
AQEGLFSHAV HAALSTVSFT LVDMDRFLFA PSVSTTTLGA LLAPGTDTDR
360 370 380 390 400
EILFLLLDAV VARAARIAAG VIAASVLKSG AGYDPLRPVC VLAEGTTFQR
410 420 430 440
TYRLRTRVTS HLQAFLTEER GVYFDIISLE NAVTLGSALG GLSS
Length:444
Mass (Da):47,845
Last modified:November 1, 1998 - v1
Checksum:i5ACC3E1100D4B07E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000520 Genomic DNA. Translation: AAC65489.1.
CP004010 Genomic DNA. Translation: AGN75694.1.
PIRiE71317.
RefSeqiNP_218946.1. NC_000919.1.
YP_008091349.1. NC_021490.2.

Genome annotation databases

EnsemblBacteriaiAAC65489; AAC65489; TP_0505.
AGN75694; AGN75694; TPANIC_0505.
GeneIDi15851791.
2611669.
KEGGitpa:TP0505.
tpw:TPANIC_0505.
PATRICi20531041. VBITrePal57110_0538.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000520 Genomic DNA. Translation: AAC65489.1 .
CP004010 Genomic DNA. Translation: AGN75694.1 .
PIRi E71317.
RefSeqi NP_218946.1. NC_000919.1.
YP_008091349.1. NC_021490.2.

3D structure databases

ProteinModelPortali O83518.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi O83518. 2 interactions.
STRINGi 243276.TP0505.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC65489 ; AAC65489 ; TP_0505 .
AGN75694 ; AGN75694 ; TPANIC_0505 .
GeneIDi 15851791.
2611669.
KEGGi tpa:TP0505.
tpw:TPANIC_0505.
PATRICi 20531041. VBITrePal57110_0538.

Phylogenomic databases

KOi K00844.
OMAi GRYMDND.
OrthoDBi EOG6TJ7TW.

Enzyme and pathway databases

BioCyci TPAL243276:GC1H-534-MONOMER.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NicholsImported.
  2. "Resequencing of Treponema pallidum ssp. pallidum strains Nichols and SS14: Correction of sequencing errors resulted in increased separation of syphilis treponeme subclusters."
    Petrosova H., Pospisilova P., Strouhal M., Cejkova D., Zobanikova M., Mikalova L., Sodergren E., Weinstock G.M., Smajs D.
    PLoS ONE 8:E74319-E74319(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NicholsImported.

Entry informationi

Entry nameiO83518_TREPA
AccessioniPrimary (citable) accession number: O83518
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: October 29, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3