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O83498

- O83498_TREPA

UniProt

O83498 - O83498_TREPA

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Protein
Submitted name:

Adenylate cyclase

Gene

TP_0485

Organism
Treponema pallidum (strain Nichols)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. adenylate cyclase activity Source: UniProtKB-EC
  2. signal transducer activity Source: InterPro

GO - Biological processi

  1. intracellular signal transduction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseImported

Enzyme and pathway databases

BioCyciTPAL243276:GC1H-512-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate cyclaseImported
Submitted name:
Putative adenylate cyclaseImported (EC:4.6.1.1Imported)
Gene namesi
Ordered Locus Names:TP_0485Imported
ORF Names:TPANIC_0485Imported
OrganismiTreponema pallidum (strain Nichols)Imported
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000000811: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

IntActiO83498. 7 interactions.
STRINGi243276.TP0485.

Structurei

3D structure databases

ProteinModelPortaliO83498.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK01768.
OMAiRIGCGIN.
OrthoDBiEOG6VQPPK.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR001054. A/G_cyclase.
IPR003660. HAMP_linker_domain.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O83498-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MSRKNANQKI VWPLTTKLIG IISTVVVLAT IAVTAMASWF FASSLHSNAE
60 70 80 90 100
LNNLAAAENF AAQIKGEFEA IATSAKSFVS LGLRSGARMH SRSALSKDFF
110 120 130 140 150
SFYPRIGYIG VGGVAELWNG DFFKKNQLRV ADARRFLADN AQVISTLQTA
160 170 180 190 200
PATLNAAPWF KAQIIAIVAP FEVDGATRNV VVIFSADVVQ HLLESGASSG
210 220 230 240 250
TMYAVTWAGN SLYHPEYSLN YSNINLQDSP VVRDLRESTQ LTKQISFIGT
260 270 280 290 300
DNKRYFGAFA KQTFGKFAIV LETPMSVVYQ AVYYAIILDG ILTGMVLLAS
310 320 330 340 350
ILLVWFIAQS ITRPILTLVG ATHAISSGQF LLDIKPSSKD EIGLLTETFV
360 370 380 390 400
SMGRGLAERE RMKEAFGKFV NRDIAEKAMK GELALGGERK TATIFFSDVR
410 420 430 440 450
SFTEMSEKLP PEDVVEFLNE YMSCMVDCIE QTGGVVDKFI GDAIMAIWGA
460 470 480 490 500
PVSLGSARLD ALQSMKAVFL MRESLIQLNE KRVACSKPRI GIGCGVNTGS
510 520 530 540 550
CVAGQIGSSK RMEYTVIGDA VNTASRIEAL NKPFGTDFLI SENTYELVKD
560 570 580 590 600
MLIVEKMPPI TVKGKREPLN VYAAINLKGH DGPQTLDELR ALLSIEKPGL
610
SADPDFEEKK CEVI
Length:614
Mass (Da):67,030
Last modified:November 1, 1998 - v1
Checksum:iDB30561FE1071BC5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000520 Genomic DNA. Translation: AAC65466.1.
CP004010 Genomic DNA. Translation: AGN75676.1.
PIRiC71320.
RefSeqiNP_218926.1. NC_000919.1.
YP_008091331.1. NC_021490.2.

Genome annotation databases

EnsemblBacteriaiAAC65466; AAC65466; TP_0485.
AGN75676; AGN75676; TPANIC_0485.
GeneIDi15851771.
2611345.
KEGGitpa:TP0485.
tpw:TPANIC_0485.
PATRICi20530995. VBITrePal57110_0517.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000520 Genomic DNA. Translation: AAC65466.1 .
CP004010 Genomic DNA. Translation: AGN75676.1 .
PIRi C71320.
RefSeqi NP_218926.1. NC_000919.1.
YP_008091331.1. NC_021490.2.

3D structure databases

ProteinModelPortali O83498.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi O83498. 7 interactions.
STRINGi 243276.TP0485.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC65466 ; AAC65466 ; TP_0485 .
AGN75676 ; AGN75676 ; TPANIC_0485 .
GeneIDi 15851771.
2611345.
KEGGi tpa:TP0485.
tpw:TPANIC_0485.
PATRICi 20530995. VBITrePal57110_0517.

Phylogenomic databases

KOi K01768.
OMAi RIGCGIN.
OrthoDBi EOG6VQPPK.

Enzyme and pathway databases

BioCyci TPAL243276:GC1H-512-MONOMER.

Family and domain databases

Gene3Di 3.30.70.1230. 1 hit.
InterProi IPR001054. A/G_cyclase.
IPR003660. HAMP_linker_domain.
IPR029787. Nucleotide_cyclase.
[Graphical view ]
Pfami PF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
[Graphical view ]
SMARTi SM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
[Graphical view ]
SUPFAMi SSF55073. SSF55073. 1 hit.
PROSITEi PS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NicholsImported.
  2. "Resequencing of Treponema pallidum ssp. pallidum strains Nichols and SS14: Correction of sequencing errors resulted in increased separation of syphilis treponeme subclusters."
    Petrosova H., Pospisilova P., Strouhal M., Cejkova D., Zobanikova M., Mikalova L., Sodergren E., Weinstock G.M., Smajs D.
    PLoS ONE 8:E74319-E74319(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NicholsImported.

Entry informationi

Entry nameiO83498_TREPA
AccessioniPrimary (citable) accession number: O83498
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: October 29, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3