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O83498 (O83498_TREPA) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Putative adenylate cyclase EMBL AGN75676.1
EC=4.6.1.1 EMBL AGN75676.1
Gene names
Ordered Locus Names:TP_0485 EMBL AAC65466.1
ORF Names:TPANIC_0485 EMBL AGN75676.1
OrganismTreponema pallidum (strain Nichols) [Complete proteome] [HAMAP] EMBL AAC65466.1
Taxonomic identifier243276 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema

Protein attributes

Sequence length614 AA.
Sequence statusComplete.
Protein existencePredicted

Ontologies

Keywords
   Molecular functionLyase EMBL AGN75676.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processintracellular signal transduction

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: InterPro

   Molecular_functionadenylate cyclase activity

Inferred from electronic annotation. Source: UniProtKB-EC

signal transducer activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
O83498 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: DB30561FE1071BC5

FASTA61467,030
        10         20         30         40         50         60 
MSRKNANQKI VWPLTTKLIG IISTVVVLAT IAVTAMASWF FASSLHSNAE LNNLAAAENF 

        70         80         90        100        110        120 
AAQIKGEFEA IATSAKSFVS LGLRSGARMH SRSALSKDFF SFYPRIGYIG VGGVAELWNG 

       130        140        150        160        170        180 
DFFKKNQLRV ADARRFLADN AQVISTLQTA PATLNAAPWF KAQIIAIVAP FEVDGATRNV 

       190        200        210        220        230        240 
VVIFSADVVQ HLLESGASSG TMYAVTWAGN SLYHPEYSLN YSNINLQDSP VVRDLRESTQ 

       250        260        270        280        290        300 
LTKQISFIGT DNKRYFGAFA KQTFGKFAIV LETPMSVVYQ AVYYAIILDG ILTGMVLLAS 

       310        320        330        340        350        360 
ILLVWFIAQS ITRPILTLVG ATHAISSGQF LLDIKPSSKD EIGLLTETFV SMGRGLAERE 

       370        380        390        400        410        420 
RMKEAFGKFV NRDIAEKAMK GELALGGERK TATIFFSDVR SFTEMSEKLP PEDVVEFLNE 

       430        440        450        460        470        480 
YMSCMVDCIE QTGGVVDKFI GDAIMAIWGA PVSLGSARLD ALQSMKAVFL MRESLIQLNE 

       490        500        510        520        530        540 
KRVACSKPRI GIGCGVNTGS CVAGQIGSSK RMEYTVIGDA VNTASRIEAL NKPFGTDFLI 

       550        560        570        580        590        600 
SENTYELVKD MLIVEKMPPI TVKGKREPLN VYAAINLKGH DGPQTLDELR ALLSIEKPGL 

       610 
SADPDFEEKK CEVI 

« Hide

References

[1]"Complete genome sequence of Treponema pallidum, the syphilis spirochete."
Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R., Gwinn M., Hickey E.K., Clayton R., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S., Peterson J., Khalak H., Richardson D., Howell J.K. expand/collapse author list , Chidambaram M., Utterback T., McDonald L., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S., Hatch B., Horst K., Roberts K., Watthey L., Weidman J., Smith H.O., Venter J.C.
Science 281:375-388(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Nichols EMBL AAC65466.1.
[2]"Resequencing of Treponema pallidum ssp. pallidum strains Nichols and SS14: Correction of sequencing errors resulted in increased separation of syphilis treponeme subclusters."
Petrosova H., Pospisilova P., Strouhal M., Cejkova D., Zobanikova M., Mikalova L., Sodergren E., Weinstock G.M., Smajs D.
PLoS ONE 8:E74319-E74319(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Nichols EMBL AGN75676.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000520 Genomic DNA. Translation: AAC65466.1.
CP004010 Genomic DNA. Translation: AGN75676.1.
PIRC71320.
RefSeqNP_218926.1. NC_000919.1.
YP_008091331.1. NC_021490.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243276.TP0485.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC65466; AAC65466; TP_0485.
AGN75676; AGN75676; TPANIC_0485.
GeneID15851771.
2611345.
KEGGtpa:TP0485.
tpw:TPANIC_0485.
PATRIC20530995. VBITrePal57110_0517.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01768.
OMARIGCGIN.
OrthoDBEOG6VQPPK.

Enzyme and pathway databases

BioCycTPAL243276:GC1H-512-MONOMER.

Family and domain databases

Gene3D3.30.70.1230. 1 hit.
InterProIPR001054. A/G_cyclase.
IPR003660. HAMP_linker_domain.
[Graphical view]
PfamPF00211. Guanylate_cyc. 1 hit.
PF00672. HAMP. 1 hit.
[Graphical view]
SMARTSM00044. CYCc. 1 hit.
SM00304. HAMP. 1 hit.
[Graphical view]
SUPFAMSSF55073. SSF55073. 1 hit.
PROSITEPS50125. GUANYLATE_CYCLASE_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameO83498_TREPA
AccessionPrimary (citable) accession number: O83498
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: July 9, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)