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O83498

- O83498_TREPA

UniProt

O83498 - O83498_TREPA

Protein
Submitted name:

Adenylate cyclase

Gene

TP_0485

Organism
Treponema pallidum (strain Nichols)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 Nov 1998)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. adenylate cyclase activity Source: UniProtKB-EC
    2. signal transducer activity Source: InterPro

    GO - Biological processi

    1. intracellular signal transduction Source: InterPro

    Keywords - Molecular functioni

    LyaseImported

    Enzyme and pathway databases

    BioCyciTPAL243276:GC1H-512-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Adenylate cyclaseImported
    Submitted name:
    Putative adenylate cyclaseImported (EC:4.6.1.1Imported)
    Gene namesi
    Ordered Locus Names:TP_0485Imported
    ORF Names:TPANIC_0485Imported
    OrganismiTreponema pallidum (strain Nichols)Imported
    Taxonomic identifieri243276 [NCBI]
    Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
    ProteomesiUP000000811: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: InterPro

    Interactioni

    Protein-protein interaction databases

    STRINGi243276.TP0485.

    Family & Domainsi

    Phylogenomic databases

    KOiK01768.
    OMAiRIGCGIN.
    OrthoDBiEOG6VQPPK.

    Family and domain databases

    Gene3Di3.30.70.1230. 1 hit.
    InterProiIPR001054. A/G_cyclase.
    IPR003660. HAMP_linker_domain.
    [Graphical view]
    PfamiPF00211. Guanylate_cyc. 1 hit.
    PF00672. HAMP. 1 hit.
    [Graphical view]
    SMARTiSM00044. CYCc. 1 hit.
    SM00304. HAMP. 1 hit.
    [Graphical view]
    SUPFAMiSSF55073. SSF55073. 1 hit.
    PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
    PS50885. HAMP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O83498-1 [UniParc]FASTAAdd to Basket

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    MSRKNANQKI VWPLTTKLIG IISTVVVLAT IAVTAMASWF FASSLHSNAE    50
    LNNLAAAENF AAQIKGEFEA IATSAKSFVS LGLRSGARMH SRSALSKDFF 100
    SFYPRIGYIG VGGVAELWNG DFFKKNQLRV ADARRFLADN AQVISTLQTA 150
    PATLNAAPWF KAQIIAIVAP FEVDGATRNV VVIFSADVVQ HLLESGASSG 200
    TMYAVTWAGN SLYHPEYSLN YSNINLQDSP VVRDLRESTQ LTKQISFIGT 250
    DNKRYFGAFA KQTFGKFAIV LETPMSVVYQ AVYYAIILDG ILTGMVLLAS 300
    ILLVWFIAQS ITRPILTLVG ATHAISSGQF LLDIKPSSKD EIGLLTETFV 350
    SMGRGLAERE RMKEAFGKFV NRDIAEKAMK GELALGGERK TATIFFSDVR 400
    SFTEMSEKLP PEDVVEFLNE YMSCMVDCIE QTGGVVDKFI GDAIMAIWGA 450
    PVSLGSARLD ALQSMKAVFL MRESLIQLNE KRVACSKPRI GIGCGVNTGS 500
    CVAGQIGSSK RMEYTVIGDA VNTASRIEAL NKPFGTDFLI SENTYELVKD 550
    MLIVEKMPPI TVKGKREPLN VYAAINLKGH DGPQTLDELR ALLSIEKPGL 600
    SADPDFEEKK CEVI 614
    Length:614
    Mass (Da):67,030
    Last modified:November 1, 1998 - v1
    Checksum:iDB30561FE1071BC5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000520 Genomic DNA. Translation: AAC65466.1.
    CP004010 Genomic DNA. Translation: AGN75676.1.
    PIRiC71320.
    RefSeqiNP_218926.1. NC_000919.1.
    YP_008091331.1. NC_021490.2.

    Genome annotation databases

    EnsemblBacteriaiAAC65466; AAC65466; TP_0485.
    AGN75676; AGN75676; TPANIC_0485.
    GeneIDi15851771.
    2611345.
    KEGGitpa:TP0485.
    tpw:TPANIC_0485.
    PATRICi20530995. VBITrePal57110_0517.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000520 Genomic DNA. Translation: AAC65466.1 .
    CP004010 Genomic DNA. Translation: AGN75676.1 .
    PIRi C71320.
    RefSeqi NP_218926.1. NC_000919.1.
    YP_008091331.1. NC_021490.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243276.TP0485.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC65466 ; AAC65466 ; TP_0485 .
    AGN75676 ; AGN75676 ; TPANIC_0485 .
    GeneIDi 15851771.
    2611345.
    KEGGi tpa:TP0485.
    tpw:TPANIC_0485.
    PATRICi 20530995. VBITrePal57110_0517.

    Phylogenomic databases

    KOi K01768.
    OMAi RIGCGIN.
    OrthoDBi EOG6VQPPK.

    Enzyme and pathway databases

    BioCyci TPAL243276:GC1H-512-MONOMER.

    Family and domain databases

    Gene3Di 3.30.70.1230. 1 hit.
    InterProi IPR001054. A/G_cyclase.
    IPR003660. HAMP_linker_domain.
    [Graphical view ]
    Pfami PF00211. Guanylate_cyc. 1 hit.
    PF00672. HAMP. 1 hit.
    [Graphical view ]
    SMARTi SM00044. CYCc. 1 hit.
    SM00304. HAMP. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55073. SSF55073. 1 hit.
    PROSITEi PS50125. GUANYLATE_CYCLASE_2. 1 hit.
    PS50885. HAMP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NicholsImported.
    2. "Resequencing of Treponema pallidum ssp. pallidum strains Nichols and SS14: Correction of sequencing errors resulted in increased separation of syphilis treponeme subclusters."
      Petrosova H., Pospisilova P., Strouhal M., Cejkova D., Zobanikova M., Mikalova L., Sodergren E., Weinstock G.M., Smajs D.
      PLoS ONE 8:E74319-E74319(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NicholsImported.

    Entry informationi

    Entry nameiO83498_TREPA
    AccessioniPrimary (citable) accession number: O83498
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1998
    Last sequence update: November 1, 1998
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3