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O83490

- 6PGL_TREPA

UniProt

O83490 - 6PGL_TREPA

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Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Treponema pallidum (strain Nichols)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-EC

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciTPAL243276:GC1H-504-MONOMER.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Short name:
6PGL
Gene namesi
Name:pgl
Synonyms:devB
Ordered Locus Names:TP_0477
OrganismiTreponema pallidum (strain Nichols)
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000000811: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2412416-phosphogluconolactonasePRO_0000090109Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243276.TP0477.

Structurei

3D structure databases

ProteinModelPortaliO83490.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0363.
KOiK01057.
OMAiENIYAID.
OrthoDBiEOG63FW46.

Family and domain databases

InterProiIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
PfamiPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01198. pgl. 1 hit.

Sequencei

Sequence statusi: Complete.

O83490-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKHIFEDAR AIAAFLVSVF DSRLKTQEIL WLALSGGSTP REIFRTWAHE
60 70 80 90 100
FRHHLDWKRL RFFWSDERCV PPTDAQSNFN MTHSALLEPL EINPDAVFRV
110 120 130 140 150
RGEDAPESAC AAYSQEIEAR LPRQRGVPCF DIILLGMGAD GHTASIFPHE
160 170 180 190 200
IELWDHSGCC VVATHPDTGQ KRVSFTGHLI NNAHEIYVVV TGREKQDMLA
210 220 230 240
SVASDPHASV PLHAWTLPKR SGCWIPLLRG LYPRKQCKPT V
Length:241
Mass (Da):27,272
Last modified:November 1, 1998 - v1
Checksum:i148FBDA12324FEF9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000520 Genomic DNA. Translation: AAC65464.1.
PIRiC71319.
RefSeqiNP_218918.1. NC_000919.1.
WP_010881926.1. NC_000919.1.

Genome annotation databases

EnsemblBacteriaiAAC65464; AAC65464; TP_0477.
GeneIDi2611121.
KEGGitpa:TP0477.
PATRICi20530979. VBITrePal57110_0509.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000520 Genomic DNA. Translation: AAC65464.1 .
PIRi C71319.
RefSeqi NP_218918.1. NC_000919.1.
WP_010881926.1. NC_000919.1.

3D structure databases

ProteinModelPortali O83490.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243276.TP0477.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC65464 ; AAC65464 ; TP_0477 .
GeneIDi 2611121.
KEGGi tpa:TP0477.
PATRICi 20530979. VBITrePal57110_0509.

Phylogenomic databases

eggNOGi COG0363.
KOi K01057.
OMAi ENIYAID.
OrthoDBi EOG63FW46.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00409 .
BioCyci TPAL243276:GC1H-504-MONOMER.

Family and domain databases

InterProi IPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view ]
Pfami PF01182. Glucosamine_iso. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01198. pgl. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nichols.

Entry informationi

Entry namei6PGL_TREPA
AccessioniPrimary (citable) accession number: O83490
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1998
Last modified: November 26, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3