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O83490

- 6PGL_TREPA

UniProt

O83490 - 6PGL_TREPA

Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Treponema pallidum (strain Nichols)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (01 Nov 1998)
      Previous versions | rss
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    Functioni

    Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

    Catalytic activityi

    6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

    Pathwayi

    GO - Molecular functioni

    1. 6-phosphogluconolactonase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pentose-phosphate shunt Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciTPAL243276:GC1H-504-MONOMER.
    UniPathwayiUPA00115; UER00409.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    6-phosphogluconolactonase (EC:3.1.1.31)
    Short name:
    6PGL
    Gene namesi
    Name:pgl
    Synonyms:devB
    Ordered Locus Names:TP_0477
    OrganismiTreponema pallidum (strain Nichols)
    Taxonomic identifieri243276 [NCBI]
    Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
    ProteomesiUP000000811: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 2412416-phosphogluconolactonasePRO_0000090109Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243276.TP0477.

    Structurei

    3D structure databases

    ProteinModelPortaliO83490.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0363.
    KOiK01057.
    OMAiENIYAID.
    OrthoDBiEOG63FW46.

    Family and domain databases

    InterProiIPR005900. 6-phosphogluconolactonase_DevB.
    IPR006148. Glc/Gal-6P_isomerase.
    [Graphical view]
    PfamiPF01182. Glucosamine_iso. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01198. pgl. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O83490-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKKHIFEDAR AIAAFLVSVF DSRLKTQEIL WLALSGGSTP REIFRTWAHE    50
    FRHHLDWKRL RFFWSDERCV PPTDAQSNFN MTHSALLEPL EINPDAVFRV 100
    RGEDAPESAC AAYSQEIEAR LPRQRGVPCF DIILLGMGAD GHTASIFPHE 150
    IELWDHSGCC VVATHPDTGQ KRVSFTGHLI NNAHEIYVVV TGREKQDMLA 200
    SVASDPHASV PLHAWTLPKR SGCWIPLLRG LYPRKQCKPT V 241
    Length:241
    Mass (Da):27,272
    Last modified:November 1, 1998 - v1
    Checksum:i148FBDA12324FEF9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000520 Genomic DNA. Translation: AAC65464.1.
    PIRiC71319.
    RefSeqiNP_218918.1. NC_000919.1.

    Genome annotation databases

    EnsemblBacteriaiAAC65464; AAC65464; TP_0477.
    GeneIDi2611121.
    KEGGitpa:TP0477.
    PATRICi20530979. VBITrePal57110_0509.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000520 Genomic DNA. Translation: AAC65464.1 .
    PIRi C71319.
    RefSeqi NP_218918.1. NC_000919.1.

    3D structure databases

    ProteinModelPortali O83490.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243276.TP0477.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC65464 ; AAC65464 ; TP_0477 .
    GeneIDi 2611121.
    KEGGi tpa:TP0477.
    PATRICi 20530979. VBITrePal57110_0509.

    Phylogenomic databases

    eggNOGi COG0363.
    KOi K01057.
    OMAi ENIYAID.
    OrthoDBi EOG63FW46.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00409 .
    BioCyci TPAL243276:GC1H-504-MONOMER.

    Family and domain databases

    InterProi IPR005900. 6-phosphogluconolactonase_DevB.
    IPR006148. Glc/Gal-6P_isomerase.
    [Graphical view ]
    Pfami PF01182. Glucosamine_iso. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01198. pgl. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Nichols.

    Entry informationi

    Entry namei6PGL_TREPA
    AccessioniPrimary (citable) accession number: O83490
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: November 1, 1998
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3