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O83490

- 6PGL_TREPA

UniProt

O83490 - 6PGL_TREPA

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Protein
6-phosphogluconolactonase
Gene
pgl, devB, TP_0477
Organism
Treponema pallidum (strain Nichols)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciTPAL243276:GC1H-504-MONOMER.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Short name:
6PGL
Gene namesi
Name:pgl
Synonyms:devB
Ordered Locus Names:TP_0477
OrganismiTreponema pallidum (strain Nichols)
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000000811: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2412416-phosphogluconolactonase
PRO_0000090109Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243276.TP0477.

Structurei

3D structure databases

ProteinModelPortaliO83490.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0363.
KOiK01057.
OMAiENIYAID.
OrthoDBiEOG63FW46.

Family and domain databases

InterProiIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
PfamiPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01198. pgl. 1 hit.

Sequencei

Sequence statusi: Complete.

O83490-1 [UniParc]FASTAAdd to Basket

« Hide

MKKHIFEDAR AIAAFLVSVF DSRLKTQEIL WLALSGGSTP REIFRTWAHE    50
FRHHLDWKRL RFFWSDERCV PPTDAQSNFN MTHSALLEPL EINPDAVFRV 100
RGEDAPESAC AAYSQEIEAR LPRQRGVPCF DIILLGMGAD GHTASIFPHE 150
IELWDHSGCC VVATHPDTGQ KRVSFTGHLI NNAHEIYVVV TGREKQDMLA 200
SVASDPHASV PLHAWTLPKR SGCWIPLLRG LYPRKQCKPT V 241
Length:241
Mass (Da):27,272
Last modified:November 1, 1998 - v1
Checksum:i148FBDA12324FEF9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000520 Genomic DNA. Translation: AAC65464.1.
PIRiC71319.
RefSeqiNP_218918.1. NC_000919.1.

Genome annotation databases

EnsemblBacteriaiAAC65464; AAC65464; TP_0477.
GeneIDi2611121.
KEGGitpa:TP0477.
PATRICi20530979. VBITrePal57110_0509.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000520 Genomic DNA. Translation: AAC65464.1 .
PIRi C71319.
RefSeqi NP_218918.1. NC_000919.1.

3D structure databases

ProteinModelPortali O83490.
ModBasei Search...

Protein-protein interaction databases

STRINGi 243276.TP0477.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC65464 ; AAC65464 ; TP_0477 .
GeneIDi 2611121.
KEGGi tpa:TP0477.
PATRICi 20530979. VBITrePal57110_0509.

Phylogenomic databases

eggNOGi COG0363.
KOi K01057.
OMAi ENIYAID.
OrthoDBi EOG63FW46.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00409 .
BioCyci TPAL243276:GC1H-504-MONOMER.

Family and domain databases

InterProi IPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view ]
Pfami PF01182. Glucosamine_iso. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01198. pgl. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nichols.

Entry informationi

Entry namei6PGL_TREPA
AccessioniPrimary (citable) accession number: O83490
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1998
Last modified: May 14, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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