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Protein
Submitted name:

DNA repair helicase, putative

Gene

TP_0380

Organism
Treponema pallidum (strain Nichols)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HelicaseImported, Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
DNA repair helicase, putativeImported
Submitted name:
Putative DNA repair helicaseImported
Gene namesi
Ordered Locus Names:TP_0380Imported
ORF Names:TPANIC_0380Imported
OrganismiTreponema pallidum (strain Nichols)Imported
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
Proteomesi
  • UP000000811 Componenti: Chromosome
  • UP000014259 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi243276.TP0380.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini250 – 406Helicase ATP-bindingInterPro annotationAdd BLAST157
Domaini460 – 606Helicase C-terminalInterPro annotationAdd BLAST147

Phylogenomic databases

eggNOGiENOG4107QIR. Bacteria.
COG1061. LUCA.
KOiK10843.
OMAiGSFGSRQ.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR032438. ERCC3_RAD25_C.
IPR006935. Helicase/UvrB_N.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR032830. XPB/Ssl2_N.
[Graphical view]
PfamiPF16203. ERCC3_RAD25_C. 1 hit.
PF13625. Helicase_C_3. 1 hit.
PF04851. ResIII. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O83395-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSVPKPLII QADRSILLDV HAPEAVAARK ALVSFAELEK SPEHLHSYRL
60 70 80 90 100
TPLSLWNAAS AGFSPQMIAQ TLTRFSRFTP PQTVLDWVVD IMSRYGKIRL
110 120 130 140 150
REDTTHSTLL RLQVRDAHIA REIAASKSLA SHLSPTTACL QDGPLPTPDT
160 170 180 190 200
ARIAQPDTTP QVQGAQTGCS YDFLLPRLHR GTVKQLLLRH GWPVHDEVPL
210 220 230 240 250
REGTPLSLRL RISPASCPPP STAYPCCHTP GTPSFVPRDY QWEAADAFVG
260 270 280 290 300
NRTQGSGFGV VVLPCGAGKT VVGLLVMGLL QTDTLILTPN SAAAQQWKRE
310 320 330 340 350
LCEKTDLDGT SIGIYSGECK EIRPVTIATY QILTWRAHAD APFSHFRLFM
360 370 380 390 400
ERSWGLIIYD EVHLLPAPLF RITAELQVVR RLGLTATLVR EDGCAQDVFS
410 420 430 440 450
LVGPKRYDVP WKDLEARGWI ARVRCVEVRV TMDRSLQYQY MTAPVRLRHR
460 470 480 490 500
LASENEAKVA VVQRLLRAHA GAPTLIIGQY VQQLLHLAHV LQVPLVSGRQ
510 520 530 540 550
TYAAREAIYQ RFREGTLQVL VVSKVANCAL DLPDASVAIQ VSGTFGSRQE
560 570 580 590 600
EAQRLGRLLR PKICDAHFYS LVTEQTVEED CALRRQRFLV EQGYTYETLR

VSEVHE
Length:606
Mass (Da):67,598
Last modified:November 1, 1998 - v1
Checksum:i9732D6DB4693809C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000520 Genomic DNA. Translation: AAC65366.1.
CP004010 Genomic DNA. Translation: AGN75575.1.
PIRiF71330.
RefSeqiWP_010881828.1. NC_021490.2.

Genome annotation databases

EnsemblBacteriaiAAC65366; AAC65366; TP_0380.
AGN75575; AGN75575; TPANIC_0380.
GeneIDi2611271.
KEGGitpa:TP_0380.
tpw:TPANIC_0380.
PATRICi20530765. VBITrePal57110_0402.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000520 Genomic DNA. Translation: AAC65366.1.
CP004010 Genomic DNA. Translation: AGN75575.1.
PIRiF71330.
RefSeqiWP_010881828.1. NC_021490.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243276.TP0380.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC65366; AAC65366; TP_0380.
AGN75575; AGN75575; TPANIC_0380.
GeneIDi2611271.
KEGGitpa:TP_0380.
tpw:TPANIC_0380.
PATRICi20530765. VBITrePal57110_0402.

Phylogenomic databases

eggNOGiENOG4107QIR. Bacteria.
COG1061. LUCA.
KOiK10843.
OMAiGSFGSRQ.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR032438. ERCC3_RAD25_C.
IPR006935. Helicase/UvrB_N.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR032830. XPB/Ssl2_N.
[Graphical view]
PfamiPF16203. ERCC3_RAD25_C. 1 hit.
PF13625. Helicase_C_3. 1 hit.
PF04851. ResIII. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO83395_TREPA
AccessioniPrimary (citable) accession number: O83395
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: November 2, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.