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Protein

RNA polymerase sigma-54 factor

Gene

rpoN

Organism
Treponema pallidum (strain Nichols)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi356 – 375H-T-H motifSequence analysisAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Nucleotidyltransferase, Sigma factor, Transferase
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma-54 factor
Gene namesi
Name:rpoN
Ordered Locus Names:TP_0111
OrganismiTreponema pallidum (strain Nichols)
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
Proteomesi
  • UP000000811 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002055451 – 475RNA polymerase sigma-54 factorAdd BLAST475

Proteomic databases

PRIDEiO83149.

Interactioni

Protein-protein interaction databases

IntActiO83149. 2 interactors.
STRINGi243276.TP0111.

Structurei

3D structure databases

ProteinModelPortaliO83149.
SMRiO83149.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi458 – 466RPON box9

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi2 – 14Gln-richAdd BLAST13

Sequence similaritiesi

Belongs to the sigma-54 factor family.Curated

Phylogenomic databases

eggNOGiENOG4105DTW. Bacteria.
COG1508. LUCA.
KOiK03092.
OMAiVTTQKFM.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR000394. RNA_pol_sigma_54.
IPR007046. RNA_pol_sigma_54_core-bd.
IPR007634. RNA_pol_sigma_54_DNA-bd.
IPR036388. WH-like_DNA-bd_sf.
PANTHERiPTHR32248. PTHR32248. 1 hit.
PfamiView protein in Pfam
PF00309. Sigma54_AID. 1 hit.
PF04963. Sigma54_CBD. 1 hit.
PF04552. Sigma54_DBD. 1 hit.
PIRSFiPIRSF000774. RpoN. 1 hit.
TIGRFAMsiTIGR02395. rpoN_sigma. 1 hit.
PROSITEiView protein in PROSITE
PS00717. SIGMA54_1. 1 hit.
PS00718. SIGMA54_2. 1 hit.
PS50044. SIGMA54_3. 1 hit.

Sequencei

Sequence statusi: Complete.

O83149-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQLVQQQRL VLNQRLVHGL CLLQLSRGDL KTEVLRAVQR NPLLEIRPSS
60 70 80 90 100
ARRTGKACYL SLGDRRERMR ARDRFQQLLE NQPDKQVDNI RAVLREQVFY
110 120 130 140 150
QKHEAIVLDL ACAFIQMLDD HGFFSISPAI FQNMCGSMPT ALQEKIPQAI
160 170 180 190 200
ALIQRLEPQG CAVFNFKESL AVQARLRFER FSDPLYRCVI NLLTHHSELL
210 220 230 240 250
FCSDNMCDGR VSVHALTTQI NSMGLCVQKV SSNDVKDILL LIKELHPFPG
260 270 280 290 300
KCVSNAQRAD TNMLLEPDVL ITKTAHGFVT QINCTGIPTV VFRNDYCMHS
310 320 330 340 350
KAAEKNHALK ACMHDALSLV SMLSYRERTL LDIAKTIVHY QCGFFDHGPA
360 370 380 390 400
KLTPLRMTDV AHRTGLSVST VSRIVRDKWL QYGSQHFSLR YFFSPRVLST
410 420 430 440 450
EEYRDRSSLG QNYPSSPHSK VSVKYRISRL IQEVRTQRIS LSDRRIAQLL
460 470
GEQGIKCARR TVNKYRSELR TCSSS
Length:475
Mass (Da):54,280
Last modified:November 1, 1998 - v1
Checksum:i2464059A019A6190
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000520 Genomic DNA. Translation: AAC65101.1.
PIRiF71364.

Genome annotation databases

EnsemblBacteriaiAAC65101; AAC65101; TP_0111.
KEGGitpa:TP_0111.

Similar proteinsi

Entry informationi

Entry nameiRP54_TREPA
AccessioniPrimary (citable) accession number: O83149
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1998
Last modified: October 25, 2017
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families