O83140 (O83140_TREPA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Rep helicase, single-stranded DNA-dependent ATPase (Rep) EMBL AAC65097.1

Gene names

Ordered Locus Names:

TP_0102

Organism

Treponema pallidum (strain Nichols) [Complete proteome] [HAMAP]

Taxonomic identifier

243276 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Treponema

Protein attributes

Sequence length	657 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	ATP + H2O = ADP + phosphate. SAAS SAAS000212
Sequence similarities	Contains 1 uvrD-like helicase ATP-binding domain. SAAS SAAS000212 Contains 1 uvrD-like helicase C-terminal domain. SAAS SAAS000212

Ontologies

Keywords
Ligand	ATP-binding DNA-binding SAAS SAAS000212 Nucleotide-binding
Molecular function	Helicase SAAS SAAS000212 EMBL AAC65097.1 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP-dependent DNA helicase activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O83140 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 6B6970BCBC38EE28	FASTA	657	75,462
	10 20 30 40 50 60 MLSTLNPEQR RAVTTLEGPL LIIAGAGSGK TRVITARIAY MLECGILQSR ILALTFTNKA 70 80 90 100 110 120 AHEMSERIKA LTGKPLRNTT VSTFHAFGVT ILREHIHVLG WRKNFSIYDE NDKRALIREA 130 140 150 160 170 180 AKEVHLLPEV LDTNCVSTLF SAIKMQRKNL KELQHKERAL WHEYHTALKL FNAVDFDDLI 190 200 210 220 230 240 VLPIQIFSEY PDILASYKSR YHYILVDEFQ DTSAQQYRLM KMLATQNICV VGDDDQSIYS 250 260 270 280 290 300 WRGAHHDNIL SFEKDFPYAT EITLEQNYRS TGTILAAANG VIAHNTQRKE KALWSGNDSG 310 320 330 340 350 360 KPIEIFNPET ERDEAIFIAN TILAEQIRAS YSFSSFGVLL RTNSFMRIIE DVFLQENIPY 370 380 390 400 410 420 RVSGGMSFFQ RKEIKDVLSY LRVISNPDDD VNLLRIINTP RRGIGKKTLH LVSDIANTQQ 430 440 450 460 470 480 CSVFNALNQI INKTHAVDLK ESHRTAVENF LQLITQARTH LLSGKNLAYK VRKFVEDIQY 490 500 510 520 530 540 FNYLIQEFQK NEHAARFKFL QIEHLVESIE HWEQSSEHGS LYDYLNRVTL LARDNVQKET 550 560 570 580 590 600 EGAVSLMTIH ASKGLEFPVV FIAGVEAGTI PHERSIEEVH SIEEERRLFY VAITRAKEKL 610 620 630 640 650 YLTHCRTRKR GGKREERTAS PFLDEIPKHL VRAHAPEGKI SEEEVTRAFT RIKKLFT

References

[1]

"Complete genome sequence of Treponema pallidum, the syphilis spirochete." Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D., Khalak H.G., Richardson D.L., Howell J.K. , Chidambaram M., Utterback T.R., McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A., Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O., Venter J.C. Science 281:375-388(1998) [PubMed: 9665876] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nichols.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000520 Genomic DNA. Translation: AAC65097.1.
PIR	B71367.
RefSeq	NP_218542.1. NC_000919.1.
3D structure databases
HSSP	HSSP built from PDB template 1PJR based on UniProtKB P56255.
ProteinModelPortal	O83140.
ModBase	Search...
Protein-protein interaction databases
IntAct	O83140. 1 interaction.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2610806.
GenomeReviews	Gene locus TP_0102 in contig AE000520_GR.
KEGG	tpa:TP0102.
NMPDR	fig|243276.1.peg.101.
PATRIC	20530153. VBITrePal57110_0113.
TIGR	TP_0102.
Phylogenomic databases
HOGENOM	HBG467281.
OMA	GGTSFFQ.
ProtClustDB	CLSK507700.
Enzyme and pathway databases
BioCyc	TPAL243276:TP_0102-MONOMER.
Family and domain databases
InterPro	IPR014017. DNA_helicase_UvrD-like_C. IPR000212. DNA_helicase_UvrD/REP. IPR014016. Helicase_SF1_UvrD-rel. [Graphical view]
KO	K03656.
PANTHER	PTHR11070. UvrD_helicase. 1 hit.
Pfam	PF00580. UvrD-helicase. 1 hit. [Graphical view]
PROSITE	PS51198. UVRD_HELICASE_ATP_BIND. 1 hit. PS51217. UVRD_HELICASE_CTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O83140_TREPA

Accession

Primary (citable) accession number: O83140

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	December 14, 2011
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)