Reviewed, UniProtKB/Swiss-Prot O83132 (PTA_TREPA)

Names and origin

Protein names

Recommended name:
    Phosphate acetyltransferase
    EC=2.3.1.8
Alternative name(s):
    Phosphotransacetylase

Gene names

Name:	pta
Ordered Locus Names:	TP_0094

Organism

Treponema pallidum [Complete proteome] [HAMAP]

Taxonomic identifier

160 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Treponema

Protein attributes

Sequence length	336 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Acetyl-CoA + phosphate = CoA + acetyl phosphate.
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphate acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 336	336	Phosphate acetyltransferase		PRO_0000179150

Sequences

	Sequence		Length	Mass (Da)
	O83132-1 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: C22586DE303135AE	FASTA	336	36,538
	10 20 30 40 50 60 MTFVESMQRR AVLAQKRLVL PEACEQRTLE AARLIVFRNI AAKVFLVGCE RDIKNTADRC 70 80 90 100 110 120 GIDLTDMVVI DPSVSKHRDQ FAERYFQKRK HKGISLAQAA EDMRDPLRFA AMMLDQGHAD 130 140 150 160 170 180 AMVAGAENTT ARVLRAGLTI IGTLPSVKTA SSCFVMDTNN PRLGGTRGLF IFSDCAVIPT 190 200 210 220 230 240 PTAEQLADIA CSAAESCRTF IGEEPTVALL SYSTKGSGGD SDENILRVRE AVRILHERRV 250 260 270 280 290 300 DFTFDGELQL DAALVPKITE KKAPHSPITG KVNTLVFPDL SSGNIGYKLV QRLSDADAYG 310 320 330 PFLQGFAKPL SDLSRGCSVE DIVAACAVTL VQSNGR

References

[1]

"Complete genome sequence of Treponema pallidum, the syphilis spirochete." Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D., Khalak H.G., Richardson D.L., Howell J.K. , Chidambaram M., Utterback T.R., McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A., Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O., Venter J.C. Science 281:375-388(1998) [PubMed: 9665876] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nichols.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE000520 Genomic DNA. Translation: AAC65090.1.
PIR	B71366.
RefSeq	NP_218534.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	O83132. 22 interactions.
Genome annotation databases
GeneID	2610744.
GenomeReviews	Gene locus TP_0094 in contig AE000520_GR.
KEGG	tpa:TP0094.
NMPDR	fig|243276.1.peg.93.
TIGR	TP_0094.
Phylogenomic databases
HOGENOM	O83132.
OMA	PDLQAGN.
Enzyme and pathway databases
BioCyc	TPAL243276:TP_0094-MON.
BRENDA	2.3.1.8. 142600.
Family and domain databases
InterPro	IPR012147. P_Ac_Bu_trans. IPR004614. P_AcTrfase. IPR002505. PTA_PTB. [Graphical view]
Pfam	PF01515. PTA_PTB. 1 hit. [Graphical view]
PIRSF	PIRSF000428. P_Ac_trans. 1 hit.
TIGRFAMs	TIGR00651. pta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTA_TREPA

Accession

Primary (citable) accession number: O83132

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1998
Last modified:	November 3, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)