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Protein

Probable proline iminopeptidase

Gene

pip

Organism
Leptolyngbya boryana (Plectonema boryanum)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically catalyzes the removal of N-terminal proline residues from peptides.By similarity

Catalytic activityi

Release of N-terminal proline from a peptide.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei110NucleophileBy similarity1
Active sitei266By similarity1
Active sitei294Proton donorBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionAminopeptidase, Hydrolase, Protease

Protein family/group databases

ESTHERiplebo-pip Proline_iminopeptidase
MEROPSiS33.001

Names & Taxonomyi

Protein namesi
Recommended name:
Probable proline iminopeptidase (EC:3.4.11.5)
Short name:
PIP
Alternative name(s):
Prolyl aminopeptidase
Short name:
PAP
Gene namesi
Name:pip
OrganismiLeptolyngbya boryana (Plectonema boryanum)
Taxonomic identifieri1184 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesLeptolyngbyaceaeLeptolyngbya

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000808441 – 321Probable proline iminopeptidaseAdd BLAST321

Proteomic databases

PRIDEiO83041

Structurei

3D structure databases

ProteinModelPortaliO83041
SMRiO83041
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 296AB hydrolase-1Sequence analysisAdd BLAST262

Sequence similaritiesi

Belongs to the peptidase S33 family.Curated

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR000073 AB_hydrolase_1
IPR002410 Peptidase_S33
IPR005944 Pro_iminopeptidase
PANTHERiPTHR43722 PTHR43722, 1 hit
PfamiView protein in Pfam
PF00561 Abhydrolase_1, 1 hit
PIRSFiPIRSF006431 Pept_S33, 1 hit
PRINTSiPR00793 PROAMNOPTASE
SUPFAMiSSF53474 SSF53474, 1 hit
TIGRFAMsiTIGR01249 pro_imino_pep_1, 1 hit

Sequencei

Sequence statusi: Complete.

O83041-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRQLYPAIAP YQSGMLPVSA LHTIYYEQSG NPNGKPVVFL HGGPGGGTIP
60 70 80 90 100
TYRQYFDPSK WRIILFDQRG AGKSTPHAEL RENTTWDLVS DIEKLRSHLN
110 120 130 140 150
IDRWFVFGGS WGSTLSLAYS QTHPDRCLGL ILRGIFLLRR KEILWFYQDG
160 170 180 190 200
ASWIFPDAWE HYLEPIPPEE RDDMISAYYR RLTSKDAEIR STAAKAWSVW
210 220 230 240 250
EGTTSRLIVD PSLQSKFADD EFADAFARIE CHYFINRGFF ETDDQLLQNC
260 270 280 290 300
DRIAHIPTVI VQGRYDVVCP MTSAWALHKA LPESELIVVP DAGHSMMEAG
310 320
ILSALIDATD RFVAQKTNGK I
Length:321
Mass (Da):36,475
Last modified:November 1, 1998 - v1
Checksum:i94EF1D7D62F5841E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB017194 Genomic DNA Translation: BAA32603.1

Similar proteinsi

Entry informationi

Entry nameiPIP_LEPBY
AccessioniPrimary (citable) accession number: O83041
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: November 1, 1998
Last modified: May 23, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

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