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Protein

Agamous-like MADS-box protein AGL19

Gene

AGL19

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Probable transcription factor that promotes flowering, especially in response to vernalization by short periods of cold, in an FLC-inpedendent manner.1 Publication

GO - Molecular functioni

GO - Biological processi

  • flower development Source: UniProtKB-KW
  • MAPK cascade Source: InterPro
  • positive regulation of transcription from RNA polymerase II promoter Source: InterPro
  • regulation of timing of transition from vegetative to reproductive phase Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW
  • vernalization response Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Flowering, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Agamous-like MADS-box protein AGL19
Gene namesi
Name:AGL19
Ordered Locus Names:At4g22950
ORF Names:F7H19.130
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G22950.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation1 Publication

GO - Cellular componenti

  • nucleus Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Decreased response to vernalization, the promotion of flowering by prolonged cold.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001994771 – 219Agamous-like MADS-box protein AGL19Add BLAST219

Proteomic databases

PaxDbiO82743.

Expressioni

Tissue specificityi

Mostly expressed in the outer layers of the root meristem (lateral root cap and epidermis) and in the central cylinder cells of mature roots. Also present in rosette leaves and seedlings and, to a lesser extent, in cauline leaves and flowers. Enriched in apices including the shoot apical meristem and developing leaf primordia.4 Publications

Inductioni

Maintained at very low levels by the polycomb-group (PcG) proteins MSI1, CLF, and EMF2 via histone methylation (H3K27me3). Derepressed upon cold treatment (vernalization).1 Publication

Gene expression databases

GenevisibleiO82743. AT.

Interactioni

Subunit structurei

Interacts with SOC1 and AGL21.1 Publication

Protein-protein interaction databases

BioGridi13683. 2 interactors.
IntActiO82743. 2 interactors.
STRINGi3702.AT4G22950.1.

Structurei

3D structure databases

ProteinModelPortaliO82743.
SMRiO82743.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 61MADS-boxPROSITE-ProRule annotationAdd BLAST61
Domaini86 – 176K-boxPROSITE-ProRule annotationAdd BLAST91

Sequence similaritiesi

Contains 1 K-box domain.PROSITE-ProRule annotation
Contains 1 MADS-box domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0014. Eukaryota.
COG5068. LUCA.
HOGENOMiHOG000155301.
InParanoidiO82743.
OMAiNIDDNME.
OrthoDBiEOG0936106C.
PhylomeDBiO82743.

Family and domain databases

CDDicd00265. MADS_MEF2_like. 1 hit.
InterProiIPR033896. MADS_MEF2-like.
IPR002487. TF_Kbox.
IPR002100. TF_MADSbox.
[Graphical view]
PfamiPF01486. K-box. 1 hit.
PF00319. SRF-TF. 1 hit.
[Graphical view]
PRINTSiPR00404. MADSDOMAIN.
SMARTiSM00432. MADS. 1 hit.
[Graphical view]
SUPFAMiSSF55455. SSF55455. 1 hit.
PROSITEiPS51297. K_BOX. 1 hit.
PS00350. MADS_BOX_1. 1 hit.
PS50066. MADS_BOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O82743-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRGKTEMKR IENATSRQVT FSKRRNGLLK KAFELSVLCD AEVALVIFSP
60 70 80 90 100
RSKLYEFSSS SIAATIERYQ RRIKEIGNNH KRNDNSQQAR DETSGLTKKI
110 120 130 140 150
EQLEISKRKL LGEGIDACSI EELQQLENQL DRSLSRIRAK KYQLLREEIE
160 170 180 190 200
KLKAEERNLV KENKDLKEKW LGMGTATIAS SQSTLSSSEV NIDDNMEVET
210
GLFIGPPETR QSKKFPPQN
Length:219
Mass (Da):25,049
Last modified:November 1, 1998 - v1
Checksum:i663740DC9D5F4A7A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF312664 mRNA. Translation: AAG37901.1.
AL031018 Genomic DNA. Translation: CAA19810.1.
AL161558 Genomic DNA. Translation: CAB79250.1.
CP002687 Genomic DNA. Translation: AEE84684.1.
AY142523 mRNA. Translation: AAN13066.1.
PIRiT05126.
RefSeqiNP_194026.1. NM_118424.2.
UniGeneiAt.2376.

Genome annotation databases

EnsemblPlantsiAT4G22950.1; AT4G22950.1; AT4G22950.
GeneIDi828394.
GrameneiAT4G22950.1; AT4G22950.1; AT4G22950.
KEGGiath:AT4G22950.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF312664 mRNA. Translation: AAG37901.1.
AL031018 Genomic DNA. Translation: CAA19810.1.
AL161558 Genomic DNA. Translation: CAB79250.1.
CP002687 Genomic DNA. Translation: AEE84684.1.
AY142523 mRNA. Translation: AAN13066.1.
PIRiT05126.
RefSeqiNP_194026.1. NM_118424.2.
UniGeneiAt.2376.

3D structure databases

ProteinModelPortaliO82743.
SMRiO82743.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi13683. 2 interactors.
IntActiO82743. 2 interactors.
STRINGi3702.AT4G22950.1.

Proteomic databases

PaxDbiO82743.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G22950.1; AT4G22950.1; AT4G22950.
GeneIDi828394.
GrameneiAT4G22950.1; AT4G22950.1; AT4G22950.
KEGGiath:AT4G22950.

Organism-specific databases

TAIRiAT4G22950.

Phylogenomic databases

eggNOGiKOG0014. Eukaryota.
COG5068. LUCA.
HOGENOMiHOG000155301.
InParanoidiO82743.
OMAiNIDDNME.
OrthoDBiEOG0936106C.
PhylomeDBiO82743.

Miscellaneous databases

PROiO82743.

Gene expression databases

GenevisibleiO82743. AT.

Family and domain databases

CDDicd00265. MADS_MEF2_like. 1 hit.
InterProiIPR033896. MADS_MEF2-like.
IPR002487. TF_Kbox.
IPR002100. TF_MADSbox.
[Graphical view]
PfamiPF01486. K-box. 1 hit.
PF00319. SRF-TF. 1 hit.
[Graphical view]
PRINTSiPR00404. MADSDOMAIN.
SMARTiSM00432. MADS. 1 hit.
[Graphical view]
SUPFAMiSSF55455. SSF55455. 1 hit.
PROSITEiPS51297. K_BOX. 1 hit.
PS00350. MADS_BOX_1. 1 hit.
PS50066. MADS_BOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAGL19_ARATH
AccessioniPrimary (citable) accession number: O82743
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 130 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.