Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cell division protein FtsZ homolog 2-1, chloroplastic

Gene

FTSZ2-1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Exhibits GTPase activity. Component of the plastid division machinery that forms a contractile ring at the division site. Required for plastid division in a dose-dependent manner.7 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei248GTPBy similarity1
Binding sitei252GTPBy similarity1
Binding sitei296GTPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi128 – 132GTPBy similarity5
Nucleotide bindingi217 – 219GTPBy similarity3

GO - Molecular functioni

  • GTPase activity Source: UniProtKB
  • GTP binding Source: UniProtKB
  • protein self-association Source: UniProtKB

GO - Biological processi

  • chloroplast fission Source: UniProtKB

Keywordsi

LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZ homolog 2-1, chloroplastic
Short name:
AtFtsZ2-1
Alternative name(s):
Plastid division protein FTSZ2-1
Gene namesi
Name:FTSZ2-1
Ordered Locus Names:At2g36250
ORF Names:F2H17.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G36250
TAIRilocus:2049455 AT2G36250

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Membrane, Plastid, Thylakoid

Pathology & Biotechi

Disruption phenotypei

Reduced number of heterogeneous large chloroplast population (small and large plastids) due to impaired plastid division.2 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi322D → A: Impaired GTPase activity. 1 Publication1
Mutagenesisi466F → A: Impaired ARC6 binding. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000406890? – 478Cell division protein FtsZ homolog 2-1, chloroplastic
Transit peptidei1 – ?ChloroplastSequence analysis

Proteomic databases

PaxDbiO82533
PRIDEiO82533

Expressioni

Gene expression databases

ExpressionAtlasiO82533 baseline and differential
GenevisibleiO82533 AT

Interactioni

Subunit structurei

Aggregates to form a contractile ring-like structure. Self-interacts and binds to FTSZ1 in heteropolymers to form two morphologically distinct types of filaments, termed type-I (smooth filaments) and -II (rough filaments), in a GTP-dependent manner. Interacts (via C-terminus) with ARC6. Part of a complex made of ARC3, ARC6, FTSZ1 and FTSZ2.5 Publications

GO - Molecular functioni

  • protein self-association Source: UniProtKB

Protein-protein interaction databases

BioGridi3541, 8 interactors
IntActiO82533, 1 interactor
STRINGi3702.AT2G36250.1

Structurei

3D structure databases

ProteinModelPortaliO82533
SMRiO82533
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FtsZ family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410IEJ4 Eukaryota
COG0206 LUCA
HOGENOMiHOG000049094
InParanoidiO82533
KOiK03531
OMAiIMNQGGV
OrthoDBiEOG093604MZ
PhylomeDBiO82533

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O82533-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATYVSPCFT PSDSRLLTVL RKNVLPENHL GRLNSIRTID SKKNRVVVAA
60 70 80 90 100
QKSESSPIRN SPRHYQSQAQ DPFLNLHPEI SMLRGEGTST IVNPRKETSS
110 120 130 140 150
GPVVEDFEEP SAPSNYNEAR IKVIGVGGGG SNAVNRMIES EMSGVEFWIV
160 170 180 190 200
NTDIQAMRMS PVLPDNRLQI GKELTRGLGA GGNPEIGMNA ARESKEVIEE
210 220 230 240 250
ALYGSDMVFV TAGMGGGTGT GAAPVIAGIA KAMGILTVGI ATTPFSFEGR
260 270 280 290 300
RRTVQAQEGL ASLRDNVDTL IVIPNDKLLT AVSQSTPVTE AFNLADDILR
310 320 330 340 350
QGVRGISDII TIPGLVNVDF ADVRAIMANA GSSLMGIGTA TGKSRARDAA
360 370 380 390 400
LNAIQSPLLD IGIERATGIV WNITGGSDLT LFEVNAAAEV IYDLVDPTAN
410 420 430 440 450
LIFGAVVDPA LSGQVSITLI ATGFKRQEEG EGRTVQMVQA DAASVGATRR
460 470
PSSSFRESGS VEIPEFLKKK GSSRYPRV
Length:478
Mass (Da):50,722
Last modified:June 1, 2002 - v2
Checksum:iA5CE7F111C962044
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF089738 mRNA Translation: AAC35987.2
AB052757 mRNA Translation: BAB68127.1
AC006921 Genomic DNA Translation: AAD21440.2
CP002685 Genomic DNA Translation: AEC09221.1
CP002685 Genomic DNA Translation: AEC09222.1
CP002685 Genomic DNA Translation: ANM61304.1
AY050844 mRNA Translation: AAK92779.1
AY091183 mRNA Translation: AAM14122.1
PIRiE84778
JC7770
RefSeqiNP_001323530.1, NM_001336588.1
NP_565839.1, NM_129183.2
NP_973612.1, NM_201883.1
UniGeneiAt.14112

Genome annotation databases

EnsemblPlantsiAT2G36250.1; AT2G36250.1; AT2G36250
AT2G36250.2; AT2G36250.2; AT2G36250
AT2G36250.3; AT2G36250.3; AT2G36250
GeneIDi818197
GrameneiAT2G36250.1; AT2G36250.1; AT2G36250
AT2G36250.2; AT2G36250.2; AT2G36250
AT2G36250.3; AT2G36250.3; AT2G36250
KEGGiath:AT2G36250

Similar proteinsi

Entry informationi

Entry nameiFTZ21_ARATH
AccessioniPrimary (citable) accession number: O82533
Secondary accession number(s): Q93VK3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: June 1, 2002
Last modified: April 25, 2018
This is version 140 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health