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Protein

Ethylene-responsive transcription factor CRF1

Gene

CRF1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the cytokinin signaling pathway involved in cotyledons, leaves, and embryos development. Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).By similarity1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi86 – 143AP2/ERFPROSITE-ProRule annotationAdd BLAST58

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • DNA binding transcription factor activity Source: TAIR

GO - Biological processi

  • cotyledon development Source: TAIR
  • cytokinin-activated signaling pathway Source: UniProtKB-KW
  • ethylene-activated signaling pathway Source: UniProtKB-KW
  • leaf development Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionActivator, DNA-binding
Biological processCytokinin signaling pathway, Ethylene signaling pathway, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Ethylene-responsive transcription factor CRF1
Alternative name(s):
Protein CYTOKININ RESPONSE FACTOR 1
Gene namesi
Name:CRF1
Synonyms:ERF063
Ordered Locus Names:At4g11140
ORF Names:F2P3.5, T22B4.120
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G11140
TAIRilocus:2136078 AT4G11140

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002979181 – 287Ethylene-responsive transcription factor CRF1Add BLAST287

Proteomic databases

PaxDbiO82503

Expressioni

Gene expression databases

ExpressionAtlasiO82503 baseline and differential
GenevisibleiO82503 AT

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi12014, 16 interactors
IntActiO82503, 18 interactors
STRINGi3702.AT4G11140.1

Structurei

3D structure databases

ProteinModelPortaliO82503
SMRiO82503
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG410IZCZ Eukaryota
ENOG410YQNQ LUCA
HOGENOMiHOG000237664
InParanoidiO82503
OMAiLFADMSF
OrthoDBiEOG09360QU2
PhylomeDBiO82503

Family and domain databases

CDDicd00018 AP2, 1 hit
Gene3Di3.30.730.10, 1 hit
InterProiView protein in InterPro
IPR001471 AP2/ERF_dom
IPR036955 AP2/ERF_dom_sf
IPR016177 DNA-bd_dom_sf
PfamiView protein in Pfam
PF00847 AP2, 1 hit
PRINTSiPR00367 ETHRSPELEMNT
SMARTiView protein in SMART
SM00380 AP2, 1 hit
SUPFAMiSSF54171 SSF54171, 1 hit
PROSITEiView protein in PROSITE
PS51032 AP2_ERF, 1 hit

Sequencei

Sequence statusi: Complete.

O82503-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METEKKVSLP RILRISVTDP YATDSSSDEE EEVDFDALST KRRRVKKYVK
60 70 80 90 100
EVVLDSVVSD KEKPMKKKRK KRVVTVPVVV TTATRKFRGV RQRPWGKWAA
110 120 130 140 150
EIRDPSRRVR VWLGTFDTAE EAAIVYDNAA IQLRGPNAEL NFPPPPVTEN
160 170 180 190 200
VEEASTEVKG VSDFIIGGGE CLRSPVSVLE SPFSGESTAV KEEFVGVSTA
210 220 230 240 250
EIVVKKEPSF NGSDFSAPLF SDDDVFGFST SMSESFGGDL FGDNLFADMS
260 270 280
FGSGFGFGSG SGFSSWHVED HFQDIGDLFG SDPVLTV
Length:287
Mass (Da):31,545
Last modified:November 1, 1998 - v1
Checksum:i2EB60595A2F11CF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY560849 mRNA Translation: AAT44916.1
AF080120 Genomic DNA Translation: AAC35537.1
AL049876 Genomic DNA Translation: CAB43049.1
AL161531 Genomic DNA Translation: CAB81215.1
CP002687 Genomic DNA Translation: AEE82977.1
BT025176 mRNA Translation: ABE77414.1
PIRiT01919
RefSeqiNP_192852.1, NM_117184.4
UniGeneiAt.33584

Genome annotation databases

EnsemblPlantsiAT4G11140.1; AT4G11140.1; AT4G11140
GeneIDi826715
GrameneiAT4G11140.1; AT4G11140.1; AT4G11140
KEGGiath:AT4G11140

Similar proteinsi

Entry informationi

Entry nameiCRF1_ARATH
AccessioniPrimary (citable) accession number: O82503
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: November 1, 1998
Last modified: April 25, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health