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Protein

Putative disease resistance protein At4g10780

Gene

At4g10780

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Potential disease resistance protein.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi180 – 1878ATPSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Plant defense

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative disease resistance protein At4g10780
Gene namesi
Ordered Locus Names:At4g10780
ORF Names:T12H20.8
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G10780.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 892891Putative disease resistance protein At4g10780PRO_0000212755Add
BLAST

Proteomic databases

PaxDbiO82484.
PRIDEiO82484.

PTM databases

iPTMnetiO82484.

Expressioni

Gene expression databases

GenevisibleiO82484. AT.

Interactioni

Protein-protein interaction databases

BioGridi11973. 1 interaction.
MINTiMINT-8069937.
STRINGi3702.AT4G10780.1.

Structurei

3D structure databases

ProteinModelPortaliO82484.
SMRiO82484. Positions 497-643.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini137 – 440304NB-ARCAdd
BLAST
Repeati515 – 53622LRR 1Add
BLAST
Repeati537 – 55923LRR 2Add
BLAST
Repeati562 – 58423LRR 3Add
BLAST
Repeati586 – 60823LRR 4Add
BLAST
Repeati609 – 63123LRR 5Add
BLAST
Repeati632 – 65423LRR 6Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili24 – 6340Sequence analysisAdd
BLAST

Domaini

The LRR repeats probably act as specificity determinant of pathogen recognition.By similarity

Sequence similaritiesi

Belongs to the disease resistance NB-LRR family.Curated
Contains 6 LRR (leucine-rich) repeats.Curated
Contains 1 NB-ARC domain.Curated

Keywords - Domaini

Coiled coil, Leucine-rich repeat, Repeat

Phylogenomic databases

eggNOGiKOG4658. Eukaryota.
COG4886. LUCA.
HOGENOMiHOG000238348.
InParanoidiO82484.
OMAiWNCEISE.
PhylomeDBiO82484.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
3.80.10.10. 2 hits.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR002182. NB-ARC.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
PF00931. NB-ARC. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O82484-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSCISLQIS CDQVLTRAYS CFFSLGNYIH KLKDNIVALE KAIEDLTATR
60 70 80 90 100
DDVLRRVQME EGKGLERLQQ VQVWLKRVEI IRNQFYDLLS ARNIEIQRLC
110 120 130 140 150
FYSNCSTNLS SSYTYGQRVF LMIKEVENLN SNGFFEIVAA PAPKLEMRPI
160 170 180 190 200
QPTIMGRETI FQRAWNRLMD DGVGTMGLYG MGGVGKTTLL TQIHNTLHDT
210 220 230 240 250
KNGVDIVIWV VVSSDLQIHK IQEDIGEKLG FIGKEWNKKQ ESQKAVDILN
260 270 280 290 300
CLSKKRFVLL LDDIWKKVDL TKIGIPSQTR ENKCKVVFTT RSLDVCARMG
310 320 330 340 350
VHDPMEVQCL STNDAWELFQ EKVGQISLGS HPDILELAKK VAGKCRGLPL
360 370 380 390 400
ALNVIGETMA GKRAVQEWHH AVDVLTSYAA EFSGMDDHIL LILKYSYDNL
410 420 430 440 450
NDKHVRSCFQ YCALYPEDYS IKKYRLIDYW ICEGFIDGNI GKERAVNQGY
460 470 480 490 500
EILGTLVRAC LLSEEGKNKL EVKMHDVVRE MALWTLSDLG KNKERCIVQA
510 520 530 540 550
GSGLRKVPKV EDWGAVRRLS LMNNGIEEIS GSPECPELTT LFLQENKSLV
560 570 580 590 600
HISGEFFRHM RKLVVLDLSE NHQLDGLPEQ ISELVALRYL DLSHTNIEGL
610 620 630 640 650
PACLQDLKTL IHLNLECMRR LGSIAGISKL SSLRTLGLRN SNIMLDVMSV
660 670 680 690 700
KELHLLEHLE ILTIDIVSTM VLEQMIDAGT LMNCMQEVSI RCLIYDQEQD
710 720 730 740 750
TKLRLPTMDS LRSLTMWNCE ISEIEIERLT WNTNPTSPCF FNLSQVIIHV
760 770 780 790 800
CSSLKDLTWL LFAPNITYLM IEQLEQLQEL ISHAKATGVT EEEQQQLHKI
810 820 830 840 850
IPFQKLQILH LSSLPELKSI YWISLSFPCL SGIYVERCPK LRKLPLDSKT
860 870 880 890
GTVGKKFVLQ YKETEWIESV EWKDEATKLH FLPSTKLVYI LS
Length:892
Mass (Da):101,802
Last modified:November 1, 1998 - v1
Checksum:iFC337F081EDB357B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF080119 Genomic DNA. Translation: AAC35528.1.
AL161518 Genomic DNA. Translation: CAB81179.1.
CP002687 Genomic DNA. Translation: AEE82928.1.
PIRiT01899.
RefSeqiNP_192816.1. NM_117146.1.
UniGeneiAt.65351.

Genome annotation databases

EnsemblPlantsiAT4G10780.1; AT4G10780.1; AT4G10780.
GeneIDi826674.
GrameneiAT4G10780.1; AT4G10780.1; AT4G10780.
KEGGiath:AT4G10780.

Cross-referencesi

Web resourcesi

NIB-LRRS

Functional and comparative genomics of disease resistance gene homologs

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF080119 Genomic DNA. Translation: AAC35528.1.
AL161518 Genomic DNA. Translation: CAB81179.1.
CP002687 Genomic DNA. Translation: AEE82928.1.
PIRiT01899.
RefSeqiNP_192816.1. NM_117146.1.
UniGeneiAt.65351.

3D structure databases

ProteinModelPortaliO82484.
SMRiO82484. Positions 497-643.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi11973. 1 interaction.
MINTiMINT-8069937.
STRINGi3702.AT4G10780.1.

PTM databases

iPTMnetiO82484.

Proteomic databases

PaxDbiO82484.
PRIDEiO82484.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G10780.1; AT4G10780.1; AT4G10780.
GeneIDi826674.
GrameneiAT4G10780.1; AT4G10780.1; AT4G10780.
KEGGiath:AT4G10780.

Organism-specific databases

TAIRiAT4G10780.

Phylogenomic databases

eggNOGiKOG4658. Eukaryota.
COG4886. LUCA.
HOGENOMiHOG000238348.
InParanoidiO82484.
OMAiWNCEISE.
PhylomeDBiO82484.

Miscellaneous databases

PROiO82484.

Gene expression databases

GenevisibleiO82484. AT.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
3.80.10.10. 2 hits.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR002182. NB-ARC.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
PF00931. NB-ARC. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
    Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
    , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
    Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.

Entry informationi

Entry nameiDRL23_ARATH
AccessioniPrimary (citable) accession number: O82484
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: November 1, 1998
Last modified: May 11, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.