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Protein

Rac-like GTP-binding protein ARAC10

Gene

ARAC10

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in local disassembly of cortical microtubules when associated with ICR5 and KIN13A.2 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi15 – 22GTPBy similarity8
Nucleotide bindingi62 – 66GTPBy similarity5
Nucleotide bindingi120 – 123GTPBy similarity4

GO - Molecular functioni

  • GTPase activity Source: InterPro
  • GTP binding Source: UniProtKB-KW
  • protein kinase binding Source: UniProtKB
  • protein phosphatase binding Source: TAIR

GO - Biological processi

  • negative regulation of abscisic acid-activated signaling pathway Source: TAIR
  • plant-type cell wall organization Source: TAIR
  • small GTPase mediated signal transduction Source: InterPro

Keywordsi

LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-194840 Rho GTPase cycle
R-ATH-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Recommended name:
Rac-like GTP-binding protein ARAC10
Alternative name(s):
GTPase protein ROP11
Gene namesi
Name:ARAC10
Synonyms:ROP11
Ordered Locus Names:At5g62880
ORF Names:MQB2.180, MQB2.20
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G62880
TAIRilocus:2170778 AT5G62880

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Membrane

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi202C → S: Affects the membrane location. 1 Publication1
Mutagenesisi208C → S: Affects the membrane location. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001989241 – 215Rac-like GTP-binding protein ARAC10Add BLAST215

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi202S-palmitoyl cysteine1 Publication1
Lipidationi208S-palmitoyl cysteine1 Publication1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiO82481
PRIDEiO82481

Expressioni

Gene expression databases

ExpressionAtlasiO82481 baseline and differential
GenevisibleiO82481 AT

Interactioni

Subunit structurei

Component of the active ARAC10-IRC5-KIN13A complex (PubMed:24280391). Interacts with ICR5 (PubMed:22984069).2 Publications

Binary interactionsi

Show more details

GO - Molecular functioni

  • protein kinase binding Source: UniProtKB
  • protein phosphatase binding Source: TAIR

Protein-protein interaction databases

BioGridi21651, 18 interactors
DIPiDIP-39043N
IntActiO82481, 18 interactors
MINTiO82481
STRINGi3702.AT5G62880.1

Structurei

3D structure databases

ProteinModelPortaliO82481
SMRiO82481
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi37 – 45Effector regionSequence analysis9

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi185 – 197Poly-LysAdd BLAST13

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rho family.Curated

Phylogenomic databases

eggNOGiKOG0393 Eukaryota
COG1100 LUCA
HOGENOMiHOG000233974
InParanoidiO82481
KOiK04392
OMAiHCPDAPV
OrthoDBiEOG09360MBN
PhylomeDBiO82481

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
IPR003578 Small_GTPase_Rho
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51420 RHO, 1 hit

Sequencei

Sequence statusi: Complete.

O82481-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSASKFIK CVTVGDGAVG KTCMLICYTS NKFPTDYIPT VFDNFSANVV
60 70 80 90 100
VEGTTVNLGL WDTAGQEDYN RLRPLSYRGA DVFVLSFSLV SRASYENVFK
110 120 130 140 150
KWIPELQHFA PGVPLVLVGT KLDLREDKHY LADHPGLSPV TTAQGEELRK
160 170 180 190 200
LIGATYYIEC SSKTQQNVKA VFDSAIKEVI KPLVKQKEKT KKKKKQKSNH
210
GCLSNVLCGR IVTRH
Length:215
Mass (Da):23,879
Last modified:November 1, 1998 - v1
Checksum:i02575631F7582E3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF079485 mRNA Translation: AAC63014.1
AF115467 Genomic DNA Translation: AAF40238.1
AB009053 Genomic DNA Translation: BAB10857.1
CP002688 Genomic DNA Translation: AED97667.1
BT002997 mRNA Translation: AAO22805.1
BT004459 mRNA Translation: AAO42453.1
PIRiT51824
RefSeqiNP_201093.1, NM_125682.5
UniGeneiAt.16939

Genome annotation databases

EnsemblPlantsiAT5G62880.1; AT5G62880.1; AT5G62880
GeneIDi836408
GrameneiAT5G62880.1; AT5G62880.1; AT5G62880
KEGGiath:AT5G62880

Similar proteinsi

Entry informationi

Entry nameiRAC10_ARATH
AccessioniPrimary (citable) accession number: O82481
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: November 1, 1998
Last modified: May 23, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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