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Protein

Rac-like GTP-binding protein ARAC7

Gene

ARAC7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Acts as a negative regulator of abscisic acid (ABA) responses.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 20GTPBy similarity8
Nucleotide bindingi60 – 64GTPBy similarity5
Nucleotide bindingi118 – 121GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Abscisic acid signaling pathway

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Rac-like GTP-binding protein ARAC7
Alternative name(s):
GTPase protein ROP9
Gene namesi
Name:ARAC7
Synonyms:ROP9
Ordered Locus Names:At4g28950
ORF Names:F25O24.70
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G28950.

Subcellular locationi

  • Membrane 1 Publication; Lipid-anchor 1 Publication

GO - Cellular componenti

  • intracellular Source: GOC
  • plasma membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi196C → S: Affects the membrane location. 1 Publication1
Mutagenesisi203C → S: Affects the membrane location. 1 Publication1
Mutagenesisi206C → S: Affects the membrane location. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001989211 – 209Rac-like GTP-binding protein ARAC7Add BLAST209

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi196S-palmitoyl cysteine1 Publication1
Lipidationi203S-palmitoyl cysteine1 Publication1
Lipidationi206S-palmitoyl cysteine1 Publication1

Post-translational modificationi

Although this sequence has a C-terminal -CXXX, it is palmitoylated at Cys-206, rather than prenylated.1 Publication

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiO82480.

Expressioni

Gene expression databases

ExpressionAtlasiO82480. baseline and differential.
GenevisibleiO82480. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G28950.1.

Structurei

Secondary structure

1209
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi6 – 14Combined sources9
Helixi19 – 28Combined sources10
Beta strandi43 – 48Combined sources6
Beta strandi53 – 59Combined sources7
Helixi73 – 75Combined sources3
Beta strandi79 – 86Combined sources8
Helixi90 – 98Combined sources9
Helixi100 – 107Combined sources8
Beta strandi113 – 118Combined sources6
Helixi120 – 123Combined sources4
Helixi126 – 131Combined sources6
Helixi138 – 148Combined sources11
Beta strandi151 – 155Combined sources5
Turni158 – 160Combined sources3
Helixi164 – 176Combined sources13

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2J0VX-ray1.78A/B/C/D1-209[»]
ProteinModelPortaliO82480.
SMRiO82480.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO82480.

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi35 – 43Effector regionSequence analysis9

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rho family.Curated

Phylogenomic databases

eggNOGiKOG0393. Eukaryota.
COG1100. LUCA.
HOGENOMiHOG000233974.
InParanoidiO82480.
KOiK04392.
OMAiGCSIASI.
OrthoDBiEOG09360LSO.
PhylomeDBiO82480.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51420. RHO. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O82480-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSASKFIKCV TVGDGAVGKT CMLICYTSNK FPTDYIPTVF DNFSANVAVD
60 70 80 90 100
GQIVNLGLWD TAGQEDYSRL RPLSYRGADI FVLAFSLISK ASYENVLKKW
110 120 130 140 150
MPELRRFAPN VPIVLVGTKL DLRDDKGYLA DHTNVITSTQ GEELRKQIGA
160 170 180 190 200
AAYIECSSKT QQNVKAVFDT AIKVVLQPPR RKEVPRRRKN HRRSGCSIAS

IVCGGCTAA
Length:209
Mass (Da):23,043
Last modified:November 1, 1998 - v1
Checksum:iFA0087A6A7650CB5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF079484 mRNA. Translation: AAC63013.1.
AF115474 Genomic DNA. Translation: AAF40246.1.
AL078469 Genomic DNA. Translation: CAB43909.1.
AL161574 Genomic DNA. Translation: CAB79653.1.
CP002687 Genomic DNA. Translation: AEE85566.1.
PIRiT08950.
RefSeqiNP_194624.1. NM_119039.3.
UniGeneiAt.3402.

Genome annotation databases

EnsemblPlantsiAT4G28950.1; AT4G28950.1; AT4G28950.
GeneIDi829016.
GrameneiAT4G28950.1; AT4G28950.1; AT4G28950.
KEGGiath:AT4G28950.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF079484 mRNA. Translation: AAC63013.1.
AF115474 Genomic DNA. Translation: AAF40246.1.
AL078469 Genomic DNA. Translation: CAB43909.1.
AL161574 Genomic DNA. Translation: CAB79653.1.
CP002687 Genomic DNA. Translation: AEE85566.1.
PIRiT08950.
RefSeqiNP_194624.1. NM_119039.3.
UniGeneiAt.3402.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2J0VX-ray1.78A/B/C/D1-209[»]
ProteinModelPortaliO82480.
SMRiO82480.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT4G28950.1.

Proteomic databases

PaxDbiO82480.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G28950.1; AT4G28950.1; AT4G28950.
GeneIDi829016.
GrameneiAT4G28950.1; AT4G28950.1; AT4G28950.
KEGGiath:AT4G28950.

Organism-specific databases

TAIRiAT4G28950.

Phylogenomic databases

eggNOGiKOG0393. Eukaryota.
COG1100. LUCA.
HOGENOMiHOG000233974.
InParanoidiO82480.
KOiK04392.
OMAiGCSIASI.
OrthoDBiEOG09360LSO.
PhylomeDBiO82480.

Miscellaneous databases

EvolutionaryTraceiO82480.
PROiO82480.

Gene expression databases

ExpressionAtlasiO82480. baseline and differential.
GenevisibleiO82480. AT.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51420. RHO. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRAC7_ARATH
AccessioniPrimary (citable) accession number: O82480
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.