O82475 (SPE1_BRAJU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Arginine decarboxylase
Short name=ADC
Short name=ARGDC
EC=4.1.1.19

Gene names

Name:

ADC1

Organism

Brassica juncea (Indian mustard) (Sinapis juncea)

Taxonomic identifier

3707 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Brassiceae › Brassica

Protein attributes

Sequence length	702 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	L-arginine = agmatine + CO2.
Cofactor	Pyridoxal phosphate. Magnesium.
Pathway	Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.
Sequence similarities	Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Ontologies

Keywords
Biological process	Putrescine biosynthesis Spermidine biosynthesis
Ligand	Magnesium Pyridoxal phosphate
Molecular function	Decarboxylase Lyase
Gene Ontology (GO)
Biological process	arginine catabolic process Inferred from electronic annotation. Source: InterPro putrescine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW spermidine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	arginine decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 702	702	Arginine decarboxylase		PRO_0000149949
Regions
	Region	325 – 335	11	Substrate-binding By similarity
Amino acid modifications
	Modified residue	141	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	O82475 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 4FF22C7A8D1B1B92	FASTA	702	76,188
	10 20 30 40 50 60 MPALALVDTP VDAFSGDCSG VFIPPSPNSS SASLDWSPSL SSSLYRIDGW GAPYFAANSS 70 80 90 100 110 120 GNISVRPHGS NTMPHQEIDL TKVVKKATDP KSSGGLALQF PLIVRFPDVL KNRLESLQSA 130 140 150 160 170 180 FEFAIQTQGY ESRYQGVYPV KCNQDRFIIE DIVEFGSSFR FGLEAGSKPE ILLAMSCLCK 190 200 210 220 230 240 GSPEAFLVCN GFKDAEYVSL ALLGRKLQLN TVIVLEQEEE LDLVIALSKK VNVRPVIGLR 250 260 270 280 290 300 AKLRTKHSGH FGSTSGEKGK FGLTTVQIIR VVRKLRDVGM LDCLQLLHFH IGSQIPSTAL 310 320 330 340 350 360 LSDGVSEAAQ LYCELVRLGA RMEVIDIGGG LGIDYDGSKS GESDLSVAYS LEEYAAAVVA 370 380 390 400 410 420 SVRFVCDQKS VKHPVICSES GRAIVSHHSV LIFEAVSAGK RHETTPSDLQ FLLEGYSEEA 430 440 450 460 470 480 RGDYENLYDA VMRGDRESCL LYVDQLKQRC VEEFKEGSLS IEQLAGVDGL CEWVTKEIGG 490 500 510 520 530 540 SDPVLTYNVN LSVFHSIPDF WGIDQLFPIV PIHRLDQRPV ARGILSDLTC DSDGKINKFI 550 560 570 580 590 600 GGESSLPLHE LDNNGYYLGM FLGGAYEEAL GGVHNLFGGP SVVRVLQKDG PHGFAVTRAM 610 620 630 640 650 660 MGQSSADVLR AMQHEPELMF QTLKHRAEEL SLVHKPGGDK GNDKLVASCL ARSFNNMPYL 670 680 690 700 SVGTSTNALT AAINNLVYYS DEAAVGNGGG CGKNGKWSYS VD

References

[1]	"Molecular cloning of an arginine decarboxylase cDNA from mustard (Brassica juncea [L.] Czern & Coss)." Mo H., Pua E.-C. Plant Gene Register PGR98-160 Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF077547 mRNA. Translation: AAC62017.1.
3D structure databases
ProteinModelPortal	O82475.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR009006. Ala_racemase/Decarboxylase_C. IPR002985. Arg_decrbxlase. IPR022643. De-COase2_C. IPR022657. De-COase2_CS. IPR022644. De-COase2_N. IPR022653. De-COase2_pyr-phos_BS. IPR000183. Orn/DAP/Arg_de-COase. [Graphical view]
Gene3D	G3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 2 hits.
PANTHER	PTHR11482:SF3. Arg_decrbxlase. 1 hit.
Pfam	PF02784. Orn_Arg_deC_N. 1 hit. PF00278. Orn_DAP_Arg_deC. 1 hit. [Graphical view]
PIRSF	PIRSF001336. Arg_decrbxlase. 1 hit.
PRINTS	PR01180. ARGDCRBXLASE. PR01179. ODADCRBXLASE.
TIGRFAMs	TIGR01273. SpeA. 1 hit.
PROSITE	PS00878. ODR_DC_2_1. 1 hit. PS00879. ODR_DC_2_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SPE1_BRAJU

Accession

Primary (citable) accession number: O82475

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	November 1, 1998
Last modified:	May 31, 2011
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program