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Protein

Ethylene-responsive transcription factor CRF5

Gene

CRF5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Component of the cytokinin signaling pathway involved in cotyledons, leaves, and embryos development. Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).By similarity1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi98 – 15558AP2/ERFPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • transcription factor activity, sequence-specific DNA binding Source: TAIR

GO - Biological processi

  • cotyledon development Source: TAIR
  • cytokinin-activated signaling pathway Source: UniProtKB-KW
  • embryo development ending in seed dormancy Source: TAIR
  • ethylene-activated signaling pathway Source: UniProtKB-KW
  • leaf development Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW
  • transcription factor import into nucleus Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Cytokinin signaling pathway, Ethylene signaling pathway, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ethylene-responsive transcription factor CRF5
Alternative name(s):
Protein CYTOKININ RESPONSE FACTOR 5
Gene namesi
Name:CRF5
Synonyms:ERF068
Ordered Locus Names:At2g46310
ORF Names:T3F17.4
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G46310.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 294294Ethylene-responsive transcription factor CRF5PRO_0000297920Add
BLAST

Proteomic databases

PaxDbiO82339.

Expressioni

Inductioni

By cytokinins.1 Publication

Gene expression databases

GenevisibleiO82339. AT.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CRF1O825033EBI-5567180,EBI-5567050
CRF2Q9SUQ24EBI-5567180,EBI-5567273
CRF3Q9FK124EBI-5567180,EBI-5567993
CRF4Q9SUE34EBI-5567180,EBI-5567027
CRF6Q9M3743EBI-5567180,EBI-5568101
ERF069Q8W4I53EBI-5567180,EBI-5568301
ERF070Q9C9953EBI-5567180,EBI-5568333

Protein-protein interaction databases

BioGridi4574. 13 interactions.
IntActiO82339. 13 interactions.
STRINGi3702.AT2G46310.1.

Structurei

3D structure databases

ProteinModelPortaliO82339.
SMRiO82339. Positions 99-154.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 AP2/ERF DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410JT8X. Eukaryota.
ENOG411082V. LUCA.
HOGENOMiHOG000237664.
InParanoidiO82339.
OMAiSHNDETE.
OrthoDBiEOG09360QU2.
PhylomeDBiO82339.

Family and domain databases

Gene3Di3.30.730.10. 1 hit.
InterProiIPR017392. AP2/ERF-transcript_factor.
IPR001471. AP2/ERF_dom.
IPR016177. DNA-bd_dom.
[Graphical view]
PANTHERiPTHR31194. PTHR31194. 1 hit.
PfamiPF00847. AP2. 1 hit.
[Graphical view]
PRINTSiPR00367. ETHRSPELEMNT.
SMARTiSM00380. AP2. 1 hit.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS51032. AP2_ERF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O82339-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSRVRKSKY TVHRKITSTP FDGFPKIVKI IVTDPCATDS SSDEENDNKS
60 70 80 90 100
VAPRVKRYVD EIRFCDEDDE PKPARKAKKK SPAAAAENGG DLVKSVVKYR
110 120 130 140 150
GVRQRPWGKF AAEIRDPSSR TRLWLGTFAT AEEAAIGYDR AAIRIKGHNA
160 170 180 190 200
QTNFLTPPPS PTTEVLPETP VIDLETVSGC DSARESQISL CSPTSVLRFS
210 220 230 240 250
HNDETEYRTE PTEEQNPFFL PDLFRSGDYF WDSEITPDPL FLDEFHQSLL
260 270 280 290
PNINNNNTVC DKDTNLSDSF PLGVIGDFSS WDVDEFFQDH LLDK
Length:294
Mass (Da):33,156
Last modified:November 1, 1998 - v1
Checksum:i5CBE0C513838C9E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005397 Genomic DNA. Translation: AAC62875.1.
CP002685 Genomic DNA. Translation: AEC10675.1.
AY074638 mRNA. Translation: AAL69454.1.
BT003121 mRNA. Translation: AAO24553.1.
AK227661 mRNA. Translation: BAE99648.1.
PIRiC84901.
RefSeqiNP_182154.1. NM_130194.4.
UniGeneiAt.37025.

Genome annotation databases

EnsemblPlantsiAT2G46310.1; AT2G46310.1; AT2G46310.
GeneIDi819239.
GrameneiAT2G46310.1; AT2G46310.1; AT2G46310.
KEGGiath:AT2G46310.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005397 Genomic DNA. Translation: AAC62875.1.
CP002685 Genomic DNA. Translation: AEC10675.1.
AY074638 mRNA. Translation: AAL69454.1.
BT003121 mRNA. Translation: AAO24553.1.
AK227661 mRNA. Translation: BAE99648.1.
PIRiC84901.
RefSeqiNP_182154.1. NM_130194.4.
UniGeneiAt.37025.

3D structure databases

ProteinModelPortaliO82339.
SMRiO82339. Positions 99-154.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4574. 13 interactions.
IntActiO82339. 13 interactions.
STRINGi3702.AT2G46310.1.

Proteomic databases

PaxDbiO82339.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G46310.1; AT2G46310.1; AT2G46310.
GeneIDi819239.
GrameneiAT2G46310.1; AT2G46310.1; AT2G46310.
KEGGiath:AT2G46310.

Organism-specific databases

TAIRiAT2G46310.

Phylogenomic databases

eggNOGiENOG410JT8X. Eukaryota.
ENOG411082V. LUCA.
HOGENOMiHOG000237664.
InParanoidiO82339.
OMAiSHNDETE.
OrthoDBiEOG09360QU2.
PhylomeDBiO82339.

Miscellaneous databases

PROiO82339.

Gene expression databases

GenevisibleiO82339. AT.

Family and domain databases

Gene3Di3.30.730.10. 1 hit.
InterProiIPR017392. AP2/ERF-transcript_factor.
IPR001471. AP2/ERF_dom.
IPR016177. DNA-bd_dom.
[Graphical view]
PANTHERiPTHR31194. PTHR31194. 1 hit.
PfamiPF00847. AP2. 1 hit.
[Graphical view]
PRINTSiPR00367. ETHRSPELEMNT.
SMARTiSM00380. AP2. 1 hit.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS51032. AP2_ERF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCRF5_ARATH
AccessioniPrimary (citable) accession number: O82339
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: November 1, 1998
Last modified: September 7, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.