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O82261 (DEGP2_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protease Do-like 2, chloroplastic
EC=3.4.21.-
Gene names
Name:DEGP2
Ordered Locus Names:At2g47940
ORF Names:F17A22.33, T9J23.7
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length607 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Serine protease that performs the primary cleavage of the photodamaged D1 protein in plant photosystem II. Ref.1

Subcellular location

Plastid › chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side Ref.1.

Induction

By high salt, desiccation and light stresses (at protein level). Ref.1

Sequence similarities

Belongs to the peptidase S1B family.

Contains 1 PDZ (DHR) domain.

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: O82261-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – ?Chloroplast Potential
Transit peptide? – 69Thylakoid
Chain70 – 607538Protease Do-like 2, chloroplastic
PRO_0000045830

Regions

Domain308 – 40396PDZ
Region118 – 317200Serine protease

Sites

Active site1591Charge relay system By similarity
Active site1901Charge relay system By similarity
Active site2681Charge relay system By similarity

Secondary structure

1 ...................................................................................... 607
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified June 1, 2002. Version 2.
Checksum: 2E1A319A4D48A9C3

FASTA60766,802
        10         20         30         40         50         60 
MAASVANCCF SVLNASVKIQ SSSISSPWCF VSASSLTPRA SSNIKRKSSR SDSPSPILNP 

        70         80         90        100        110        120 
EKNYPGRVRD ESSNPPQKMA FKAFGSPKKE KKESLSDFSR DQQTDPAKIH DASFLNAVVK 

       130        140        150        160        170        180 
VYCTHTAPDY SLPWQKQRQF TSTGSAFMIG DGKLLTNAHC VEHDTQVKVK RRGDDRKYVA 

       190        200        210        220        230        240 
KVLVRGVDCD IALLSVESED FWKGAEPLRL GHLPRLQDSV TVVGYPLGGD TISVTKGVVS 

       250        260        270        280        290        300 
RIEVTSYAHG SSDLLGIQID AAINPGNSGG PAFNDQGECI GVAFQVYRSE ETENIGYVIP 

       310        320        330        340        350        360 
TTVVSHFLTD YERNGKYTGY PCLGVLLQKL ENPALRECLK VPTNEGVLVR RVEPTSDASK 

       370        380        390        400        410        420 
VLKEGDVIVS FDDLHVGCEG TVPFRSSERI AFRYLISQKF AGDIAEIGII RAGEHKKVQV 

       430        440        450        460        470        480 
VLRPRVHLVP YHIDGGQPSY IIVAGLVFTP LSEPLIEEEC EDTIGLKLLT KARYSVARFR 

       490        500        510        520        530        540 
GEQIVILSQV LANEVNIGYE DMNNQQVLKF NGIPIRNIHH LAHLIDMCKD KYLVFEFEDN 

       550        560        570        580        590        600 
YVAVLEREAS NSASLCILKD YGIPSERSAD LLEPYVDPID DTQALDQGIG DSPVSNLEIG 


FDGLVWA

« Hide

References

« Hide 'large scale' references
[1]"A chloroplast DegP2 protease performs the primary cleavage of the photodamaged D1 protein in plant photosystem II."
Haussuhl K., Andersson B., Adamska I.
EMBO J. 20:713-722(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, INDUCTION.
[2]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Chloroplast and mitochondrial proteases in Arabidopsis. A proposed nomenclature."
Adam Z., Adamska I., Nakabayashi K., Ostersetzer O., Haussuhl K., Manuell A., Zheng B., Vallon O., Rodermel S.R., Shinozaki K., Clarke A.K.
Plant Physiol. 125:1912-1918(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF245171 mRNA. Translation: AAK14061.1.
AC005309 Genomic DNA. Translation: AAC63648.2.
AC006072 Genomic DNA. Translation: AAM15122.1.
CP002685 Genomic DNA. Translation: AEC10914.1.
AF326865 mRNA. Translation: AAG41447.1.
AF349516 mRNA. Translation: AAK15563.1.
AY075700 mRNA. Translation: AAL77706.1.
AY102139 mRNA. Translation: AAM26706.1.
IPIIPI00542397.
PIRD84921.
RefSeqNP_566115.1. NM_130361.4.
UniGeneAt.12952.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4FLNX-ray2.80A/B/C71-607[»]
ProteinModelPortalO82261.
SMRO82261. Positions 110-577.
ModBaseSearch...

Protein-protein interaction databases

STRING3702.AT2G47940.1-P.

Protein family/group databases

MEROPSS01.279.

Proteomic databases

PaxDbO82261.
PRIDEO82261.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G47940.1; AT2G47940.1; AT2G47940.
GeneID819406.
KEGGath:AT2G47940.

Organism-specific databases

GeneFarm2418. 199.
TAIRAt2g47940.

Phylogenomic databases

eggNOGCOG0265.
HOGENOMHOG000239474.
InParanoidO82261.
OMAFRSTERI.
PhylomeDBO82261.
ProtClustDBCLSN2688994.

Gene expression databases

ArrayExpressO82261.
GenevestigatorO82261.
GermOnlineAT2G47940. Arabidopsis thaliana.

Family and domain databases

InterProIPR001478. PDZ.
IPR015724. Pept_DepP2.
IPR001254. Peptidase_S1.
IPR001940. Peptidase_S1C.
IPR009003. Trypsin-like_Pept_dom.
[Graphical view]
PANTHERPTHR22939:SF1. PTHR22939:SF1. 1 hit.
PfamPF13180. PDZ_2. 1 hit.
PF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSPR00834. PROTEASES2C.
SUPFAMSSF50156. PDZ. 1 hit.
SSF50494. Pept_Ser_Cys. 1 hit.
PROSITEPS50106. PDZ. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDEGP2_ARATH
AccessionPrimary (citable) accession number: O82261
Secondary accession number(s): Q9FPE9
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: June 1, 2002
Last modified: May 1, 2013
This is version 94 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Peptidase families

Classification of peptidase families and list of entries

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents