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Protein

G-type lectin S-receptor-like serine/threonine-protein kinase B120

Gene

B120

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei557ATPPROSITE-ProRule annotation1
Active sitei654Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi535 – 543ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Lectin, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
G-type lectin S-receptor-like serine/threonine-protein kinase B120 (EC:2.7.11.1)
Gene namesi
Name:B120
Ordered Locus Names:At4g21390
ORF Names:F18E5.10, T6K22.120
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G21390.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini26 – 438ExtracellularSequence analysisAdd BLAST413
Transmembranei439 – 459HelicalSequence analysisAdd BLAST21
Topological domaini460 – 849CytoplasmicSequence analysisAdd BLAST390

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: TAIR
  • plasmodesma Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000040129726 – 849G-type lectin S-receptor-like serine/threonine-protein kinase B120Add BLAST824

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi110N-linked (GlcNAc...)Sequence analysis1
Glycosylationi191N-linked (GlcNAc...)Sequence analysis1
Glycosylationi210N-linked (GlcNAc...)Sequence analysis1
Glycosylationi230N-linked (GlcNAc...)Sequence analysis1
Glycosylationi273N-linked (GlcNAc...)Sequence analysis1
Glycosylationi282N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi299 ↔ 311By similarity
Disulfide bondi305 ↔ 320By similarity
Glycosylationi333N-linked (GlcNAc...)Sequence analysis1
Glycosylationi349N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi381 ↔ 402By similarity
Disulfide bondi385 ↔ 391By similarity
Glycosylationi388N-linked (GlcNAc...)Sequence analysis1
Modified residuei658PhosphoserineBy similarity1
Modified residuei671PhosphoserineBy similarity1
Modified residuei688PhosphothreonineBy similarity1

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

PaxDbiO81906.
PRIDEiO81906.

Expressioni

Gene expression databases

GenevisibleiO81906. AT.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi13182. 3 interactors.
STRINGi3702.AT4G21390.1.

Structurei

3D structure databases

ProteinModelPortaliO81906.
SMRiO81906.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 153Bulb-type lectinPROSITE-ProRule annotationAdd BLAST128
Domaini295 – 332EGF-like; atypicalAdd BLAST38
Domaini346 – 427PANPROSITE-ProRule annotationAdd BLAST82
Domaini529 – 814Protein kinasePROSITE-ProRule annotationAdd BLAST286

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni618 – 635CaM-bindingBy similarityAdd BLAST18

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 1 bulb-type lectin domain.PROSITE-ProRule annotation
Contains 1 EGF-like domain.Curated
Contains 1 PAN domain.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

EGF-like domain, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IE3D. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116559.
InParanoidiO81906.
OMAiYTHGRSE.
OrthoDBiEOG09360269.
PhylomeDBiO81906.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
2.90.10.10. 1 hit.
InterProiIPR001480. Bulb-type_lectin_dom.
IPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR003609. Pan_app.
IPR000719. Prot_kinase_dom.
IPR000858. S_locus_glycoprot_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR024171. SRK-like_kinase.
[Graphical view]
PfamiPF01453. B_lectin. 1 hit.
PF08276. PAN_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
PF00954. S_locus_glycop. 1 hit.
[Graphical view]
PIRSFiPIRSF000641. SRK. 1 hit.
SMARTiSM00108. B_lectin. 1 hit.
SM00473. PAN_AP. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF51110. SSF51110. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50927. BULB_LECTIN. 1 hit.
PS50948. PAN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O81906-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFFRKTSLY LSLFLYFFLY ESSMAANTIR RGESLRDGIN HKPLVSPQKT
60 70 80 90 100
FELGFFSPGS STHRFLGIWY GNIEDKAVVW VANRATPISD QSGVLMISND
110 120 130 140 150
GNLVLLDGKN ITVWSSNIES STTNNNNRVV SIHDTGNFVL SETDTDRPIW
160 170 180 190 200
ESFNHPTDTF LPQMRVRVNP QTGDNHAFVS WRSETDPSPG NYSLGVDPSG
210 220 230 240 250
APEIVLWEGN KTRKWRSGQW NSAIFTGIPN MSLLTNYLYG FKLSSPPDET
260 270 280 290 300
GSVYFTYVPS DPSVLLRFKV LYNGTEEELR WNETLKKWTK FQSEPDSECD
310 320 330 340 350
QYNRCGKFGI CDMKGSNGIC SCIHGYEQVS VGNWSRGCRR RTPLKCERNI
360 370 380 390 400
SVGEDEFLTL KSVKLPDFEI PEHNLVDPED CRERCLRNCS CNAYSLVGGI
410 420 430 440 450
GCMIWNQDLV DLQQFEAGGS SLHIRLADSE VGENRKTKIA VIVAVLVGVI
460 470 480 490 500
LIGIFALLLW RFKRKKDVSG AYCGKNTDTS VVVADLTKSK ETTSAFSGSV
510 520 530 540 550
DIMIEGKAVN TSELPVFSLN AIAIATNDFC KENELGRGGF GPVYKGVLED
560 570 580 590 600
GREIAVKRLS GKSGQGVDEF KNEIILIAKL QHRNLVRLLG CCFEGEEKML
610 620 630 640 650
VYEYMPNKSL DFFLFDETKQ ALIDWKLRFS IIEGIARGLL YLHRDSRLRI
660 670 680 690 700
IHRDLKVSNV LLDAEMNPKI SDFGMARIFG GNQNEANTVR VVGTYGYMSP
710 720 730 740 750
EYAMEGLFSV KSDVYSFGVL LLEIVSGKRN TSLRSSEHGS LIGYAWYLYT
760 770 780 790 800
HGRSEELVDP KIRVTCSKRE ALRCIHVAML CVQDSAAERP NMASVLLMLE
810 820 830 840
SDTATLAAPR QPTFTSTRRN SIDVNFALDS SQQYIVSSNE ITSTVVLGR
Length:849
Mass (Da):95,168
Last modified:November 1, 1998 - v1
Checksum:i03FEB8CF57FD6F67
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti795V → A in BAF01045 (Ref. 4) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF637083 Genomic DNA. Translation: ABV21215.1.
AL022603 Genomic DNA. Translation: CAA18703.1.
AL031187 Genomic DNA. Translation: CAA20204.1.
AL161555 Genomic DNA. Translation: CAB81246.1.
CP002687 Genomic DNA. Translation: AEE84447.1.
AK229175 mRNA. Translation: BAF01045.1.
PIRiT05181.
RefSeqiNP_193870.1. NM_118259.4.
UniGeneiAt.32633.

Genome annotation databases

EnsemblPlantsiAT4G21390.1; AT4G21390.1; AT4G21390.
GeneIDi827891.
GrameneiAT4G21390.1; AT4G21390.1; AT4G21390.
KEGGiath:AT4G21390.

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF637083 Genomic DNA. Translation: ABV21215.1.
AL022603 Genomic DNA. Translation: CAA18703.1.
AL031187 Genomic DNA. Translation: CAA20204.1.
AL161555 Genomic DNA. Translation: CAB81246.1.
CP002687 Genomic DNA. Translation: AEE84447.1.
AK229175 mRNA. Translation: BAF01045.1.
PIRiT05181.
RefSeqiNP_193870.1. NM_118259.4.
UniGeneiAt.32633.

3D structure databases

ProteinModelPortaliO81906.
SMRiO81906.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi13182. 3 interactors.
STRINGi3702.AT4G21390.1.

Proteomic databases

PaxDbiO81906.
PRIDEiO81906.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G21390.1; AT4G21390.1; AT4G21390.
GeneIDi827891.
GrameneiAT4G21390.1; AT4G21390.1; AT4G21390.
KEGGiath:AT4G21390.

Organism-specific databases

TAIRiAT4G21390.

Phylogenomic databases

eggNOGiENOG410IE3D. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116559.
InParanoidiO81906.
OMAiYTHGRSE.
OrthoDBiEOG09360269.
PhylomeDBiO81906.

Miscellaneous databases

PROiO81906.

Gene expression databases

GenevisibleiO81906. AT.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
2.90.10.10. 1 hit.
InterProiIPR001480. Bulb-type_lectin_dom.
IPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR003609. Pan_app.
IPR000719. Prot_kinase_dom.
IPR000858. S_locus_glycoprot_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR024171. SRK-like_kinase.
[Graphical view]
PfamiPF01453. B_lectin. 1 hit.
PF08276. PAN_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
PF00954. S_locus_glycop. 1 hit.
[Graphical view]
PIRSFiPIRSF000641. SRK. 1 hit.
SMARTiSM00108. B_lectin. 1 hit.
SM00473. PAN_AP. 1 hit.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF51110. SSF51110. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50927. BULB_LECTIN. 1 hit.
PS50948. PAN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB120_ARATH
AccessioniPrimary (citable) accession number: O81906
Secondary accession number(s): Q0WPA4, Q9SVK2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 30, 2010
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 134 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.