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Protein

Probable disease resistance protein At4g27220

Gene

At4g27220

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Probable disease resistance protein.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi141 – 148ATPSequence analysis8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Plant defense

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable disease resistance protein At4g27220
Gene namesi
Ordered Locus Names:At4g27220
ORF Names:M4I22.30
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G27220.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002127601 – 919Probable disease resistance protein At4g27220Add BLAST919

Proteomic databases

PaxDbiO81825.
PRIDEiO81825.

Expressioni

Gene expression databases

GenevisibleiO81825. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G27220.1.

Structurei

3D structure databases

ProteinModelPortaliO81825.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini121 – 399NB-ARCAdd BLAST279
Repeati447 – 468LRR 1Add BLAST22
Repeati469 – 492LRR 2Add BLAST24
Repeati494 – 516LRR 3Add BLAST23
Repeati519 – 540LRR 4Add BLAST22
Repeati542 – 564LRR 5Add BLAST23
Repeati565 – 587LRR 6Add BLAST23
Repeati588 – 610LRR 7Add BLAST23
Repeati611 – 635LRR 8Add BLAST25

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1 – 30Sequence analysisAdd BLAST30
Coiled coili74 – 95Sequence analysisAdd BLAST22

Domaini

The LRR repeats probably act as specificity determinant of pathogen recognition.By similarity

Sequence similaritiesi

Belongs to the disease resistance NB-LRR family.Curated
Contains 8 LRR (leucine-rich) repeats.Curated
Contains 1 NB-ARC domain.Curated

Keywords - Domaini

Coiled coil, Leucine-rich repeat, Repeat

Phylogenomic databases

eggNOGiKOG4658. Eukaryota.
COG4886. LUCA.
HOGENOMiHOG000091014.
InParanoidiO81825.
OMAiINCPEAS.
OrthoDBiEOG093602JL.
PhylomeDBiO81825.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
3.80.10.10. 2 hits.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR002182. NB-ARC.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
PF00931. NB-ARC. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 4 hits.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

O81825-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRSNARALN RALERLKNVQ TKVNEALKRS GIQEKSLERK LRIWLRKVEE
60 70 80 90 100
NVPLGELILE KRSSCAIWLS DKDVEILEKV KRLEEQGQDL IKKISVNKSS
110 120 130 140 150
REIVERVLGP SFHPQKTALE MLDKLKDCLK KKNVQKIGVW GMGGVGKTTL
160 170 180 190 200
VRTLNNDLLK YAATQQFALV IWVTVSKDFD LKRVQMDIAK RLGKRFTREQ
210 220 230 240 250
MNQLGLTICE RLIDLKNFLL ILDDVWHPID LDQLGIPLAL ERSKDSKVVL
260 270 280 290 300
TSRRLEVCQQ MMTNENIKVA CLQEKEAWEL FCHNVGEVAN SDNVKPIAKD
310 320 330 340 350
VSHECCGLPL AIITIGRTLR GKPQVEVWKH TLNLLKRSAP SIDTEEKIFG
360 370 380 390 400
TLKLSYDFLQ DNMKSCFLFC ALFPEDYSIK VSELIMYWVA EGLLDGQHHY
410 420 430 440 450
EDMMNEGVTL VERLKDSCLL EDGDSCDTVK MHDVVRDFAI WFMSSQGEGF
460 470 480 490 500
HSLVMAGRGL IEFPQDKFVS SVQRVSLMAN KLERLPNNVI EGVETLVLLL
510 520 530 540 550
QGNSHVKEVP NGFLQAFPNL RILDLSGVRI RTLPDSFSNL HSLRSLVLRN
560 570 580 590 600
CKKLRNLPSL ESLVKLQFLD LHESAIRELP RGLEALSSLR YICVSNTYQL
610 620 630 640 650
QSIPAGTILQ LSSLEVLDMA GSAYSWGIKG EEREGQATLD EVTCLPHLQF
660 670 680 690 700
LAIKLLDVLS FSYEFDSLTK RLTKFQFLFS PIRSVSPPGT GEGCLAISDV
710 720 730 740 750
NVSNASIGWL LQHVTSLDLN YCEGLNGMFE NLVTKSKSSF VAMKALSIHY
760 770 780 790 800
FPSLSLASGC ESQLDLFPNL EELSLDNVNL ESIGELNGFL GMRLQKLKLL
810 820 830 840 850
QVSGCRQLKR LFSDQILAGT LPNLQEIKVV SCLRLEELFN FSSVPVDFCA
860 870 880 890 900
ESLLPKLTVI KLKYLPQLRS LCNDRVVLES LEHLEVESCE SLKNLPFVPG
910
NTGMINEQMA WEYMSRTLG
Length:919
Mass (Da):103,914
Last modified:November 1, 1998 - v1
Checksum:i3C844D04ADC00CD3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL030978 Genomic DNA. Translation: CAA19716.1.
AL161566 Genomic DNA. Translation: CAB79577.1.
CP002687 Genomic DNA. Translation: AEE85312.1.
DQ446872 mRNA. Translation: ABE66093.1.
PIRiT05746.
RefSeqiNP_194452.1. NM_118856.1.
UniGeneiAt.65426.

Genome annotation databases

EnsemblPlantsiAT4G27220.1; AT4G27220.1; AT4G27220.
GeneIDi828830.
GrameneiAT4G27220.1; AT4G27220.1; AT4G27220.
KEGGiath:AT4G27220.

Cross-referencesi

Web resourcesi

NIB-LRRS

Functional and comparative genomics of disease resistance gene homologs

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL030978 Genomic DNA. Translation: CAA19716.1.
AL161566 Genomic DNA. Translation: CAB79577.1.
CP002687 Genomic DNA. Translation: AEE85312.1.
DQ446872 mRNA. Translation: ABE66093.1.
PIRiT05746.
RefSeqiNP_194452.1. NM_118856.1.
UniGeneiAt.65426.

3D structure databases

ProteinModelPortaliO81825.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT4G27220.1.

Proteomic databases

PaxDbiO81825.
PRIDEiO81825.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G27220.1; AT4G27220.1; AT4G27220.
GeneIDi828830.
GrameneiAT4G27220.1; AT4G27220.1; AT4G27220.
KEGGiath:AT4G27220.

Organism-specific databases

TAIRiAT4G27220.

Phylogenomic databases

eggNOGiKOG4658. Eukaryota.
COG4886. LUCA.
HOGENOMiHOG000091014.
InParanoidiO81825.
OMAiINCPEAS.
OrthoDBiEOG093602JL.
PhylomeDBiO81825.

Miscellaneous databases

PROiO81825.

Gene expression databases

GenevisibleiO81825. AT.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
3.80.10.10. 2 hits.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR002182. NB-ARC.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13855. LRR_8. 1 hit.
PF00931. NB-ARC. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 4 hits.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
SSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDRL28_ARATH
AccessioniPrimary (citable) accession number: O81825
Secondary accession number(s): Q1PE46
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: November 1, 1998
Last modified: October 5, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.