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Protein

Probable protein phosphatase 2C 21

Gene

PPC4-2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi57Manganese 1By similarity1
Metal bindingi57Manganese 2By similarity1
Metal bindingi58Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi272Manganese 2By similarity1
Metal bindingi320Manganese 2By similarity1

GO - Molecular functioni

GO - Biological processi

  • response to abscisic acid Source: TAIR

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 21 (EC:3.1.3.16)
Short name:
AtPP2C21
Alternative name(s):
AtPPC4;2
Gene namesi
Name:PPC4-2
Ordered Locus Names:At2g25070
ORF Names:F13D4.1, F27C12
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G25070
TAIRilocus:2047344 AT2G25070

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679511 – 355Probable protein phosphatase 2C 21Add BLAST355

Proteomic databases

PaxDbiO81716
PRIDEiO81716

PTM databases

iPTMnetiO81716

Expressioni

Gene expression databases

ExpressionAtlasiO81716 baseline and differential
GenevisibleiO81716 AT

Interactioni

Protein-protein interaction databases

BioGridi2397, 1 interactor
IntActiO81716, 1 interactor
MINTiO81716
STRINGi3702.AT2G25070.1

Structurei

3D structure databases

ProteinModelPortaliO81716
SMRiO81716
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 329PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST307

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0698 Eukaryota
COG0631 LUCA
HOGENOMiHOG000233896
InParanoidiO81716
KOiK17499
OMAiGSMQGYR
OrthoDBiEOG09360AF5
PhylomeDBiO81716

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR000222 PP2C_BS
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 2 hits
SMARTiView protein in SMART
SM00331 PP2C_SIG, 1 hit
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 2 hits
PROSITEiView protein in PROSITE
PS01032 PPM_1, 1 hit
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

O81716-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGTYLSSPKT EKLSEDGEND KLRFGLSSMQ GWRATMEDAH AAILDLDDKT
60 70 80 90 100
SFFGVYDGHG GKVVAKFCAK YLHQQVISNE AYKTGDVETS LRRAFFRMDD
110 120 130 140 150
MMQGQRGWRE LAVLGDKMNK FSGMIEGFIW SPRSGDTNNQ PDSWPLEDGP
160 170 180 190 200
HSDFTGPTSG CTACVALIKD KKLFVANAGD SRCVISRKSQ AYNLSKDHKP
210 220 230 240 250
DLEVEKERIL KAGGFIHAGR INGSLNLTRA IGDMEFKQNK FLPSEKQMVT
260 270 280 290 300
ADPDINTIDL CDDDDFLVVA CDGIWDCMSS QELVDFIHEQ LKSETKLSTV
310 320 330 340 350
CEKVVDRCLA PDTATGEGCD NMTIILVQFK KPNPSETEPE DSKPEPSEDE

PSSSS
Length:355
Mass (Da):39,354
Last modified:November 1, 1998 - v1
Checksum:iCAD638796203C746
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB079671 mRNA Translation: BAB84700.1
AC006585 Genomic DNA Translation: AAD23006.1
CP002685 Genomic DNA Translation: AEC07654.1
CP002685 Genomic DNA Translation: ANM62333.1
AY050873 mRNA Translation: AAK92810.1
AY091209 mRNA Translation: AAM14148.1
PIRiH84643
RefSeqiNP_001324497.1, NM_001335973.1
NP_180079.1, NM_128064.3
UniGeneiAt.24404

Genome annotation databases

EnsemblPlantsiAT2G25070.1; AT2G25070.1; AT2G25070
AT2G25070.2; AT2G25070.2; AT2G25070
GeneIDi817045
GrameneiAT2G25070.1; AT2G25070.1; AT2G25070
AT2G25070.2; AT2G25070.2; AT2G25070
KEGGiath:AT2G25070

Similar proteinsi

Entry informationi

Entry nameiP2C21_ARATH
AccessioniPrimary (citable) accession number: O81716
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 1, 1998
Last modified: May 23, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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