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Protein

Probable protein phosphatase 2C 21

Gene

PPC4-2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi57Manganese 1By similarity1
Metal bindingi57Manganese 2By similarity1
Metal bindingi58Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi272Manganese 2By similarity1
Metal bindingi320Manganese 2By similarity1

GO - Molecular functioni

GO - Biological processi

  • response to abscisic acid Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 21 (EC:3.1.3.16)
Short name:
AtPP2C21
Alternative name(s):
AtPPC4;2
Gene namesi
Name:PPC4-2
Ordered Locus Names:At2g25070
ORF Names:F13D4.1, F27C12
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G25070.

Subcellular locationi

GO - Cellular componenti

  • plasma membrane Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679511 – 355Probable protein phosphatase 2C 21Add BLAST355

Proteomic databases

PaxDbiO81716.

PTM databases

iPTMnetiO81716.

Expressioni

Gene expression databases

GenevisibleiO81716. AT.

Interactioni

Protein-protein interaction databases

BioGridi2397. 1 interactor.
IntActiO81716. 1 interactor.
MINTiMINT-8390663.
STRINGi3702.AT2G25070.1.

Structurei

3D structure databases

ProteinModelPortaliO81716.
SMRiO81716.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 329PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST307

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0698. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000233896.
InParanoidiO81716.
KOiK17499.
OMAiICEDLMD.
OrthoDBiEOG09360AF5.
PhylomeDBiO81716.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 2 hits.
PfamiPF00481. PP2C. 2 hits.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O81716-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGTYLSSPKT EKLSEDGEND KLRFGLSSMQ GWRATMEDAH AAILDLDDKT
60 70 80 90 100
SFFGVYDGHG GKVVAKFCAK YLHQQVISNE AYKTGDVETS LRRAFFRMDD
110 120 130 140 150
MMQGQRGWRE LAVLGDKMNK FSGMIEGFIW SPRSGDTNNQ PDSWPLEDGP
160 170 180 190 200
HSDFTGPTSG CTACVALIKD KKLFVANAGD SRCVISRKSQ AYNLSKDHKP
210 220 230 240 250
DLEVEKERIL KAGGFIHAGR INGSLNLTRA IGDMEFKQNK FLPSEKQMVT
260 270 280 290 300
ADPDINTIDL CDDDDFLVVA CDGIWDCMSS QELVDFIHEQ LKSETKLSTV
310 320 330 340 350
CEKVVDRCLA PDTATGEGCD NMTIILVQFK KPNPSETEPE DSKPEPSEDE

PSSSS
Length:355
Mass (Da):39,354
Last modified:November 1, 1998 - v1
Checksum:iCAD638796203C746
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB079671 mRNA. Translation: BAB84700.1.
AC006585 Genomic DNA. Translation: AAD23006.1.
CP002685 Genomic DNA. Translation: AEC07654.1.
AY050873 mRNA. Translation: AAK92810.1.
AY091209 mRNA. Translation: AAM14148.1.
PIRiH84643.
RefSeqiNP_180079.1. NM_128064.3.
UniGeneiAt.24404.

Genome annotation databases

EnsemblPlantsiAT2G25070.1; AT2G25070.1; AT2G25070.
GeneIDi817045.
GrameneiAT2G25070.1; AT2G25070.1; AT2G25070.
KEGGiath:AT2G25070.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB079671 mRNA. Translation: BAB84700.1.
AC006585 Genomic DNA. Translation: AAD23006.1.
CP002685 Genomic DNA. Translation: AEC07654.1.
AY050873 mRNA. Translation: AAK92810.1.
AY091209 mRNA. Translation: AAM14148.1.
PIRiH84643.
RefSeqiNP_180079.1. NM_128064.3.
UniGeneiAt.24404.

3D structure databases

ProteinModelPortaliO81716.
SMRiO81716.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi2397. 1 interactor.
IntActiO81716. 1 interactor.
MINTiMINT-8390663.
STRINGi3702.AT2G25070.1.

PTM databases

iPTMnetiO81716.

Proteomic databases

PaxDbiO81716.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G25070.1; AT2G25070.1; AT2G25070.
GeneIDi817045.
GrameneiAT2G25070.1; AT2G25070.1; AT2G25070.
KEGGiath:AT2G25070.

Organism-specific databases

TAIRiAT2G25070.

Phylogenomic databases

eggNOGiKOG0698. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000233896.
InParanoidiO81716.
KOiK17499.
OMAiICEDLMD.
OrthoDBiEOG09360AF5.
PhylomeDBiO81716.

Miscellaneous databases

PROiO81716.

Gene expression databases

GenevisibleiO81716. AT.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 2 hits.
PfamiPF00481. PP2C. 2 hits.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiP2C21_ARATH
AccessioniPrimary (citable) accession number: O81716
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.