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O81716 (P2C21_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C 21

Short name=AtPP2C21
EC=3.1.3.16
Alternative name(s):
AtPPC4;2
Gene names
Name:PPC4-2
Ordered Locus Names:At2g25070
ORF Names:F13D4.1, F27C12
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length355 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 355355Probable protein phosphatase 2C 21
PRO_0000367951

Regions

Domain22 – 322301PP2C-like

Sites

Metal binding571Manganese 1 By similarity
Metal binding571Manganese 2 By similarity
Metal binding581Manganese 1; via carbonyl oxygen By similarity
Metal binding2721Manganese 2 By similarity
Metal binding3201Manganese 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
O81716 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: CAD638796203C746

FASTA35539,354
        10         20         30         40         50         60 
MGTYLSSPKT EKLSEDGEND KLRFGLSSMQ GWRATMEDAH AAILDLDDKT SFFGVYDGHG 

        70         80         90        100        110        120 
GKVVAKFCAK YLHQQVISNE AYKTGDVETS LRRAFFRMDD MMQGQRGWRE LAVLGDKMNK 

       130        140        150        160        170        180 
FSGMIEGFIW SPRSGDTNNQ PDSWPLEDGP HSDFTGPTSG CTACVALIKD KKLFVANAGD 

       190        200        210        220        230        240 
SRCVISRKSQ AYNLSKDHKP DLEVEKERIL KAGGFIHAGR INGSLNLTRA IGDMEFKQNK 

       250        260        270        280        290        300 
FLPSEKQMVT ADPDINTIDL CDDDDFLVVA CDGIWDCMSS QELVDFIHEQ LKSETKLSTV 

       310        320        330        340        350 
CEKVVDRCLA PDTATGEGCD NMTIILVQFK KPNPSETEPE DSKPEPSEDE PSSSS 

« Hide

References

« Hide 'large scale' references
[1]"Substrate specificity of type 2C protein phosphatases (PP2C) in Arabidopsis thaliana."
Izumi S., Yamada M., Ohsato H., Miyazaki S., Bohnert H.J., Fukuhara T.
Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
[6]"Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks."
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A., Grossmann J., Gruissem W., Baginsky S.
Plant Physiol. 150:889-903(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB079671 mRNA. Translation: BAB84700.1.
AC006585 Genomic DNA. Translation: AAD23006.1.
CP002685 Genomic DNA. Translation: AEC07654.1.
AY050873 mRNA. Translation: AAK92810.1.
AY091209 mRNA. Translation: AAM14148.1.
PIRH84643.
RefSeqNP_180079.1. NM_128064.2.
UniGeneAt.24404.

3D structure databases

ProteinModelPortalO81716.
SMRO81716. Positions 1-330.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid2397. 1 interaction.
IntActO81716. 1 interaction.
MINTMINT-8390663.
STRING3702.AT2G25070.1-P.

Proteomic databases

PaxDbO81716.
PRIDEO81716.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G25070.1; AT2G25070.1; AT2G25070.
GeneID817045.
KEGGath:AT2G25070.

Organism-specific databases

TAIRAT2G25070.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000233896.
InParanoidO81716.
KOK17499.
OMADPDINTI.
PhylomeDBO81716.

Enzyme and pathway databases

BioCycARA:AT2G25070-MONOMER.

Gene expression databases

GenevestigatorO81716.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 2 hits.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. SSF81606. 2 hits.
PROSITEPS01032. PP2C. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROO81716.

Entry information

Entry nameP2C21_ARATH
AccessionPrimary (citable) accession number: O81716
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 1, 1998
Last modified: May 14, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names