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Reviewed, UniProtKB/Swiss-Prot O81701 (POLC4_ALNGL)

Last modified November 24, 2009. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Polcalcin Aln g 4
Alternative name(s):
    Calcium-binding pollen allergen Aln g 4
    Allergen=Aln g 4
OrganismAlnus glutinosa (Alder)
Taxonomic identifier3517 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonscore eudicotyledonsrosidseurosids IFagalesBetulaceaeAlnus

Protein attributes

Sequence length85 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Allergenic properties

Causes an allergic reaction in human.

Sequence similarities

Contains 2 EF-hand domains.

Mass spectrometry

Molecular mass is 9318.6 Da from positions 1 - 85. Determined by MALDI. Ref.1

Ontologies

Keywords
   DiseaseAllergen
   DomainRepeat
   LigandCalcium
Gene Ontology (GO)
   Molecular functioncalcium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 8585Polcalcin Aln g 4
PRO_0000073663

Regions

Domain7 – 4236EF-hand 1
Domain42 – 7736EF-hand 2
Calcium binding20 – 31121 Potential
Calcium binding55 – 66122 Potential

Sequences

Sequence LengthMass (Da)Tools
O81701-1 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 903774CC1F714FAD

FASTA859,362
        10         20         30         40         50         60 
MADDHPQDQA EHERIFKCFD ANGDGKISAS ELGDALKTLG SVTPDEVKHM MAEIDTDGDG 

        70         80 
FISFQEFTNF ARANRGLVKD VAKIF 

« Hide

References

[1]"Molecular and immunologic characterization of a highly cross-reactive two EF-hand calcium-binding alder pollen allergen, Aln g 4: structural basis for calcium-modulated IgE recognition."
Hayek B., Vangelista L., Pastore A., Sperr W.R., Valent P., Vrtala S., Niederberger V., Twardosz A., Kraft D., Valenta R.
J. Immunol. 161:7031-7039(1998) [PubMed: 9862740] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], CHARACTERIZATION, MASS SPECTROMETRY.
Tissue: Pollen.

Cross-references

Sequence databases

Y17713 mRNA. Translation: CAA76831.1.

3D structure databases

SMRO81701. Positions 2-85.
ModBaseSearch...

Family and domain databases

InterProIPR011992. EF-Hand_type.
IPR018247. EF_Hand_1_Ca_BS.
IPR018249. EF_HAND_2.
IPR002048. EF_hand_Ca_bd.
IPR018248. EF_Hand_dom.
[Graphical view]
Gene3DG3DSA:1.10.238.10. EF-Hand_type. 1 hit.
PfamPF00036. efhand. 2 hits.
[Graphical view]
SMARTSM00054. EFh. 2 hits.
[Graphical view]
PROSITEPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePOLC4_ALNGL
AccessionPrimary (citable) accession number: O81701
Entry history
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: November 1, 1998
Last modified: November 24, 2009
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Relevant documents

Allergens

Nomenclature of allergens and list of entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents