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O81292

- LRK43_ARATH

UniProt

O81292 - LRK43_ARATH

Protein

L-type lectin-domain containing receptor kinase IV.3

Gene

LECRK43

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 122 (01 Oct 2014)
      Sequence version 1 (01 Nov 1998)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei384 – 3841ATPPROSITE-ProRule annotation
    Active sitei480 – 4801Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi361 – 3699ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. carbohydrate binding Source: InterPro
    3. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Receptor, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Lectin, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciARA:AT4G02410-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    L-type lectin-domain containing receptor kinase IV.3 (EC:2.7.11.1)
    Short name:
    LecRK-IV.3
    Gene namesi
    Name:LECRK43
    Ordered Locus Names:At4g02410
    ORF Names:T14P8.3
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 4

    Organism-specific databases

    TAIRiAT4G02410.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2222Sequence AnalysisAdd
    BLAST
    Chaini23 – 674652L-type lectin-domain containing receptor kinase IV.3PRO_0000403087Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi21 – 211N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi28 – 281N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi40 – 401N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi81 – 811N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi136 – 1361N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi188 – 1881N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PRIDEiO81292.

    Expressioni

    Gene expression databases

    GenevestigatoriO81292.

    Interactioni

    Protein-protein interaction databases

    IntActiO81292. 8 interactions.
    STRINGi3702.AT4G02410.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliO81292.
    SMRiO81292. Positions 23-266, 327-630.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini23 – 296274ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini318 – 674357CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei297 – 31721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini355 – 632278Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni26 – 263238Legume-lectin likeAdd
    BLAST

    Sequence similaritiesi

    In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Curated
    In the N-terminal section; belongs to the leguminous lectin family.Curated
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000116555.
    InParanoidiO81292.
    OMAiDWAQRFR.
    PhylomeDBiO81292.

    Family and domain databases

    Gene3Di2.60.120.200. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR011009. Kinase-like_dom.
    IPR019825. Lectin_legB_Mn/Ca_BS.
    IPR001220. Legume_lectin_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00139. Lectin_legB. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEiPS00307. LECTIN_LEGUME_BETA. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    O81292-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFFKLFTIFF FFIILLSKPL NSSSQSLNFT YNSFHRPPTN ISIQGIATVT    50
    SNGILKLTDK TVISTGHAFY TEPIRFKDSP NDTVSSFSTT FVIGIYSGIP 100
    TISGHGMAFF IAPNPVLSSA MASQYLGLFS STNNGNDTNH ILAVEFDTIM 150
    NPEFDDTNDN HVGININSLT SVKSSLVGYW DEINQFNNLT LISRKRMQVW 200
    VDYDDRTNQI DVTMAPFGEV KPRKALVSVV RDLSSVFLQD MYLGFSAATG 250
    YVLSEHFVFG WSFMVKGKTA PPLTLSKVPK FPRVGPTSLQ RFYKNRMPLF 300
    SLLLIPVLFV VSLIFLVRFI VRRRRKFAEE FEDWETEFGK NRLRFKDLYY 350
    ATKGFKDKDL LGSGGFGRVY RGVMPTTKKE IAVKRVSNES RQGLKEFVAE 400
    IVSIGRMSHR NLVPLLGYCR RRDELLLVYD YMPNGSLDKY LYDCPEVTLD 450
    WKQRFNVIIG VASGLFYLHE EWEQVVIHRD IKASNVLLDA EYNGRLGDFG 500
    LARLCDHGSD PQTTRVVGTW GYLAPDHVRT GRATTATDVF AFGVLLLEVA 550
    CGRRPIEIEI ESDESVLLVD SVFGFWIEGN ILDATDPNLG SVYDQREVET 600
    VLKLGLLCSH SDPQVRPTMR QVLQYLRGDA TLPDLSPLDF RGSGKMLGMN 650
    HRFSESCTFS SGSSIAYSIV SGGR 674
    Length:674
    Mass (Da):75,923
    Last modified:November 1, 1998 - v1
    Checksum:i757FF9AFCF5A774D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF069298 Genomic DNA. Translation: AAC19286.1.
    AL161494 Genomic DNA. Translation: CAB80734.1.
    CP002687 Genomic DNA. Translation: AEE82167.1.
    AY094440 mRNA. Translation: AAM19812.1.
    AY094476 mRNA. Translation: AAM19843.1.
    PIRiT01309.
    RefSeqiNP_567233.1. NM_116474.3.
    UniGeneiAt.34304.

    Genome annotation databases

    EnsemblPlantsiAT4G02410.1; AT4G02410.1; AT4G02410.
    GeneIDi828032.
    KEGGiath:AT4G02410.

    Cross-referencesi

    Web resourcesi

    PlantP kinase Classification PPC

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF069298 Genomic DNA. Translation: AAC19286.1 .
    AL161494 Genomic DNA. Translation: CAB80734.1 .
    CP002687 Genomic DNA. Translation: AEE82167.1 .
    AY094440 mRNA. Translation: AAM19812.1 .
    AY094476 mRNA. Translation: AAM19843.1 .
    PIRi T01309.
    RefSeqi NP_567233.1. NM_116474.3.
    UniGenei At.34304.

    3D structure databases

    ProteinModelPortali O81292.
    SMRi O81292. Positions 23-266, 327-630.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi O81292. 8 interactions.
    STRINGi 3702.AT4G02410.1-P.

    Proteomic databases

    PRIDEi O81292.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT4G02410.1 ; AT4G02410.1 ; AT4G02410 .
    GeneIDi 828032.
    KEGGi ath:AT4G02410.

    Organism-specific databases

    GeneFarmi 170. 4.
    TAIRi AT4G02410.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000116555.
    InParanoidi O81292.
    OMAi DWAQRFR.
    PhylomeDBi O81292.

    Enzyme and pathway databases

    BioCyci ARA:AT4G02410-MONOMER.

    Gene expression databases

    Genevestigatori O81292.

    Family and domain databases

    Gene3Di 2.60.120.200. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR011009. Kinase-like_dom.
    IPR019825. Lectin_legB_Mn/Ca_BS.
    IPR001220. Legume_lectin_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00139. Lectin_legB. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEi PS00307. LECTIN_LEGUME_BETA. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
      Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
      , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
      Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. Cited for: GENE FAMILY.
    5. "Arabidopsis L-type lectin receptor kinases: phylogeny, classification, and expression profiles."
      Bouwmeester K., Govers F.
      J. Exp. Bot. 60:4383-4396(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiLRK43_ARATH
    AccessioniPrimary (citable) accession number: O81292
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 11, 2011
    Last sequence update: November 1, 1998
    Last modified: October 1, 2014
    This is version 122 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3