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O81292 (LRK43_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 113. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
L-type lectin-domain containing receptor kinase IV.3
Short name=LecRK-IV.3
EC=2.7.11.1
Gene names
Name:LECRK43
Ordered Locus Names:At4g02410
ORF Names:T14P8.3
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length674 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Subcellular location

Cell membrane; Single-pass type I membrane protein By similarity.

Sequence similarities

In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

In the N-terminal section; belongs to the leguminous lectin family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 674652L-type lectin-domain containing receptor kinase IV.3
PRO_0000403087

Regions

Topological domain23 – 296274Extracellular Potential
Transmembrane297 – 31721Helical; Potential
Topological domain318 – 674357Cytoplasmic Potential
Domain355 – 632278Protein kinase
Nucleotide binding361 – 3699ATP By similarity
Region26 – 263238Legume-lectin like

Sites

Active site4801Proton acceptor By similarity
Binding site3841ATP By similarity

Amino acid modifications

Glycosylation211N-linked (GlcNAc...) Potential
Glycosylation281N-linked (GlcNAc...) Potential
Glycosylation401N-linked (GlcNAc...) Potential
Glycosylation811N-linked (GlcNAc...) Potential
Glycosylation1361N-linked (GlcNAc...) Potential
Glycosylation1881N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
O81292 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 757FF9AFCF5A774D

FASTA67475,923
        10         20         30         40         50         60 
MFFKLFTIFF FFIILLSKPL NSSSQSLNFT YNSFHRPPTN ISIQGIATVT SNGILKLTDK 

        70         80         90        100        110        120 
TVISTGHAFY TEPIRFKDSP NDTVSSFSTT FVIGIYSGIP TISGHGMAFF IAPNPVLSSA 

       130        140        150        160        170        180 
MASQYLGLFS STNNGNDTNH ILAVEFDTIM NPEFDDTNDN HVGININSLT SVKSSLVGYW 

       190        200        210        220        230        240 
DEINQFNNLT LISRKRMQVW VDYDDRTNQI DVTMAPFGEV KPRKALVSVV RDLSSVFLQD 

       250        260        270        280        290        300 
MYLGFSAATG YVLSEHFVFG WSFMVKGKTA PPLTLSKVPK FPRVGPTSLQ RFYKNRMPLF 

       310        320        330        340        350        360 
SLLLIPVLFV VSLIFLVRFI VRRRRKFAEE FEDWETEFGK NRLRFKDLYY ATKGFKDKDL 

       370        380        390        400        410        420 
LGSGGFGRVY RGVMPTTKKE IAVKRVSNES RQGLKEFVAE IVSIGRMSHR NLVPLLGYCR 

       430        440        450        460        470        480 
RRDELLLVYD YMPNGSLDKY LYDCPEVTLD WKQRFNVIIG VASGLFYLHE EWEQVVIHRD 

       490        500        510        520        530        540 
IKASNVLLDA EYNGRLGDFG LARLCDHGSD PQTTRVVGTW GYLAPDHVRT GRATTATDVF 

       550        560        570        580        590        600 
AFGVLLLEVA CGRRPIEIEI ESDESVLLVD SVFGFWIEGN ILDATDPNLG SVYDQREVET 

       610        620        630        640        650        660 
VLKLGLLCSH SDPQVRPTMR QVLQYLRGDA TLPDLSPLDF RGSGKMLGMN HRFSESCTFS 

       670 
SGSSIAYSIV SGGR

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B. expand/collapse author list , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Lectin receptor kinases in plants."
Barre A., Herve C., Lescure B., Rouge P.
Crit. Rev. Plant Sci. 21:379-399(2002)
Cited for: GENE FAMILY.
[5]"Arabidopsis L-type lectin receptor kinases: phylogeny, classification, and expression profiles."
Bouwmeester K., Govers F.
J. Exp. Bot. 60:4383-4396(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF069298 Genomic DNA. Translation: AAC19286.1.
AL161494 Genomic DNA. Translation: CAB80734.1.
CP002687 Genomic DNA. Translation: AEE82167.1.
AY094440 mRNA. Translation: AAM19812.1.
AY094476 mRNA. Translation: AAM19843.1.
IPIIPI00529591.
PIRT01309.
RefSeqNP_567233.1. NM_116474.3.
UniGeneAt.34304.

3D structure databases

ProteinModelPortalO81292.
SMRO81292. Positions 23-266, 327-630.
ModBaseSearch...

Protein-protein interaction databases

IntActO81292. 8 interactions.
STRING3702.AT4G02410.1-P.

Proteomic databases

PRIDEO81292.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT4G02410.1; AT4G02410.1; AT4G02410.
GeneID828032.
KEGGath:AT4G02410.

Organism-specific databases

GeneFarm170. 4.
TAIRAt4g02410.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000116555.
InParanoidO81292.
OMADINANHA.
PhylomeDBO81292.
ProtClustDBCLSN2683086.

Gene expression databases

GenevestigatorO81292.

Family and domain databases

Gene3D2.60.120.200. 1 hit.
InterProIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR011009. Kinase-like_dom.
IPR019825. Lectin_legB_Mn/Ca_BS.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_cat_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF49899. ConA_like_lec_gl. 1 hit.
SSF56112. Kinase_like. 1 hit.
PROSITEPS00307. LECTIN_LEGUME_BETA. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLRK43_ARATH
AccessionPrimary (citable) accession number: O81292
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: November 1, 1998
Last modified: May 29, 2013
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·Documents