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O81292

- LRK43_ARATH

UniProt

O81292 - LRK43_ARATH

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Protein

L-type lectin-domain containing receptor kinase IV.3

Gene
LECRK43, At4g02410, T14P8.3
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei384 – 3841ATP By similarity
Active sitei480 – 4801Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi361 – 3699ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. carbohydrate binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Lectin, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT4G02410-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
L-type lectin-domain containing receptor kinase IV.3 (EC:2.7.11.1)
Short name:
LecRK-IV.3
Gene namesi
Name:LECRK43
Ordered Locus Names:At4g02410
ORF Names:T14P8.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 4

Organism-specific databases

TAIRiAT4G02410.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini23 – 296274Extracellular Reviewed predictionAdd
BLAST
Transmembranei297 – 31721Helical; Reviewed predictionAdd
BLAST
Topological domaini318 – 674357Cytoplasmic Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222 Reviewed predictionAdd
BLAST
Chaini23 – 674652L-type lectin-domain containing receptor kinase IV.3PRO_0000403087Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi21 – 211N-linked (GlcNAc...) Reviewed prediction
Glycosylationi28 – 281N-linked (GlcNAc...) Reviewed prediction
Glycosylationi40 – 401N-linked (GlcNAc...) Reviewed prediction
Glycosylationi81 – 811N-linked (GlcNAc...) Reviewed prediction
Glycosylationi136 – 1361N-linked (GlcNAc...) Reviewed prediction
Glycosylationi188 – 1881N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiO81292.

Expressioni

Gene expression databases

GenevestigatoriO81292.

Interactioni

Protein-protein interaction databases

IntActiO81292. 8 interactions.
STRINGi3702.AT4G02410.1-P.

Structurei

3D structure databases

ProteinModelPortaliO81292.
SMRiO81292. Positions 23-266, 327-630.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini355 – 632278Protein kinaseAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni26 – 263238Legume-lectin likeAdd
BLAST

Sequence similaritiesi

In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
In the N-terminal section; belongs to the leguminous lectin family.

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000116555.
InParanoidiO81292.
OMAiDWAQRFR.
PhylomeDBiO81292.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR011009. Kinase-like_dom.
IPR019825. Lectin_legB_Mn/Ca_BS.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00307. LECTIN_LEGUME_BETA. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O81292-1 [UniParc]FASTAAdd to Basket

« Hide

MFFKLFTIFF FFIILLSKPL NSSSQSLNFT YNSFHRPPTN ISIQGIATVT    50
SNGILKLTDK TVISTGHAFY TEPIRFKDSP NDTVSSFSTT FVIGIYSGIP 100
TISGHGMAFF IAPNPVLSSA MASQYLGLFS STNNGNDTNH ILAVEFDTIM 150
NPEFDDTNDN HVGININSLT SVKSSLVGYW DEINQFNNLT LISRKRMQVW 200
VDYDDRTNQI DVTMAPFGEV KPRKALVSVV RDLSSVFLQD MYLGFSAATG 250
YVLSEHFVFG WSFMVKGKTA PPLTLSKVPK FPRVGPTSLQ RFYKNRMPLF 300
SLLLIPVLFV VSLIFLVRFI VRRRRKFAEE FEDWETEFGK NRLRFKDLYY 350
ATKGFKDKDL LGSGGFGRVY RGVMPTTKKE IAVKRVSNES RQGLKEFVAE 400
IVSIGRMSHR NLVPLLGYCR RRDELLLVYD YMPNGSLDKY LYDCPEVTLD 450
WKQRFNVIIG VASGLFYLHE EWEQVVIHRD IKASNVLLDA EYNGRLGDFG 500
LARLCDHGSD PQTTRVVGTW GYLAPDHVRT GRATTATDVF AFGVLLLEVA 550
CGRRPIEIEI ESDESVLLVD SVFGFWIEGN ILDATDPNLG SVYDQREVET 600
VLKLGLLCSH SDPQVRPTMR QVLQYLRGDA TLPDLSPLDF RGSGKMLGMN 650
HRFSESCTFS SGSSIAYSIV SGGR 674
Length:674
Mass (Da):75,923
Last modified:November 1, 1998 - v1
Checksum:i757FF9AFCF5A774D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF069298 Genomic DNA. Translation: AAC19286.1.
AL161494 Genomic DNA. Translation: CAB80734.1.
CP002687 Genomic DNA. Translation: AEE82167.1.
AY094440 mRNA. Translation: AAM19812.1.
AY094476 mRNA. Translation: AAM19843.1.
PIRiT01309.
RefSeqiNP_567233.1. NM_116474.3.
UniGeneiAt.34304.

Genome annotation databases

EnsemblPlantsiAT4G02410.1; AT4G02410.1; AT4G02410.
GeneIDi828032.
KEGGiath:AT4G02410.

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF069298 Genomic DNA. Translation: AAC19286.1 .
AL161494 Genomic DNA. Translation: CAB80734.1 .
CP002687 Genomic DNA. Translation: AEE82167.1 .
AY094440 mRNA. Translation: AAM19812.1 .
AY094476 mRNA. Translation: AAM19843.1 .
PIRi T01309.
RefSeqi NP_567233.1. NM_116474.3.
UniGenei At.34304.

3D structure databases

ProteinModelPortali O81292.
SMRi O81292. Positions 23-266, 327-630.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi O81292. 8 interactions.
STRINGi 3702.AT4G02410.1-P.

Proteomic databases

PRIDEi O81292.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT4G02410.1 ; AT4G02410.1 ; AT4G02410 .
GeneIDi 828032.
KEGGi ath:AT4G02410.

Organism-specific databases

GeneFarmi 170. 4.
TAIRi AT4G02410.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000116555.
InParanoidi O81292.
OMAi DWAQRFR.
PhylomeDBi O81292.

Enzyme and pathway databases

BioCyci ARA:AT4G02410-MONOMER.

Gene expression databases

Genevestigatori O81292.

Family and domain databases

Gene3Di 2.60.120.200. 1 hit.
InterProi IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR011009. Kinase-like_dom.
IPR019825. Lectin_legB_Mn/Ca_BS.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEi PS00307. LECTIN_LEGUME_BETA. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
    Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
    , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
    Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. Cited for: GENE FAMILY.
  5. "Arabidopsis L-type lectin receptor kinases: phylogeny, classification, and expression profiles."
    Bouwmeester K., Govers F.
    J. Exp. Bot. 60:4383-4396(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiLRK43_ARATH
AccessioniPrimary (citable) accession number: O81292
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: November 1, 1998
Last modified: May 14, 2014
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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