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Protein

L-type lectin-domain containing receptor kinase IV.3

Gene

LECRK43

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei384ATPPROSITE-ProRule annotation1
Active sitei480Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi361 – 369ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Lectin, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
L-type lectin-domain containing receptor kinase IV.3 (EC:2.7.11.1)
Short name:
LecRK-IV.3
Gene namesi
Name:LECRK43
Ordered Locus Names:At4g02410
ORF Names:T14P8.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G02410.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini23 – 296ExtracellularSequence analysisAdd BLAST274
Transmembranei297 – 317HelicalSequence analysisAdd BLAST21
Topological domaini318 – 674CytoplasmicSequence analysisAdd BLAST357

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000040308723 – 674L-type lectin-domain containing receptor kinase IV.3Add BLAST652

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi21N-linked (GlcNAc...)Sequence analysis1
Glycosylationi28N-linked (GlcNAc...)Sequence analysis1
Glycosylationi40N-linked (GlcNAc...)Sequence analysis1
Glycosylationi81N-linked (GlcNAc...)Sequence analysis1
Glycosylationi136N-linked (GlcNAc...)Sequence analysis1
Glycosylationi188N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiO81292.

Expressioni

Gene expression databases

GenevisibleiO81292. AT.

Interactioni

Protein-protein interaction databases

IntActiO81292. 8 interactors.
STRINGi3702.AT4G02410.1.

Structurei

3D structure databases

ProteinModelPortaliO81292.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini355 – 632Protein kinasePROSITE-ProRule annotationAdd BLAST278

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni26 – 263Legume-lectin likeAdd BLAST238

Sequence similaritiesi

In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Curated
In the N-terminal section; belongs to the leguminous lectin family.Curated
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IEGM. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116555.
InParanoidiO81292.
OMAiGMATEIT.
OrthoDBiEOG0936040C.
PhylomeDBiO81292.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR031049. LecRK.
IPR019825. Lectin_legB_Mn/Ca_BS.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PANTHERiPTHR27007:SF13. PTHR27007:SF13. 1 hit.
PfamiPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00307. LECTIN_LEGUME_BETA. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O81292-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFFKLFTIFF FFIILLSKPL NSSSQSLNFT YNSFHRPPTN ISIQGIATVT
60 70 80 90 100
SNGILKLTDK TVISTGHAFY TEPIRFKDSP NDTVSSFSTT FVIGIYSGIP
110 120 130 140 150
TISGHGMAFF IAPNPVLSSA MASQYLGLFS STNNGNDTNH ILAVEFDTIM
160 170 180 190 200
NPEFDDTNDN HVGININSLT SVKSSLVGYW DEINQFNNLT LISRKRMQVW
210 220 230 240 250
VDYDDRTNQI DVTMAPFGEV KPRKALVSVV RDLSSVFLQD MYLGFSAATG
260 270 280 290 300
YVLSEHFVFG WSFMVKGKTA PPLTLSKVPK FPRVGPTSLQ RFYKNRMPLF
310 320 330 340 350
SLLLIPVLFV VSLIFLVRFI VRRRRKFAEE FEDWETEFGK NRLRFKDLYY
360 370 380 390 400
ATKGFKDKDL LGSGGFGRVY RGVMPTTKKE IAVKRVSNES RQGLKEFVAE
410 420 430 440 450
IVSIGRMSHR NLVPLLGYCR RRDELLLVYD YMPNGSLDKY LYDCPEVTLD
460 470 480 490 500
WKQRFNVIIG VASGLFYLHE EWEQVVIHRD IKASNVLLDA EYNGRLGDFG
510 520 530 540 550
LARLCDHGSD PQTTRVVGTW GYLAPDHVRT GRATTATDVF AFGVLLLEVA
560 570 580 590 600
CGRRPIEIEI ESDESVLLVD SVFGFWIEGN ILDATDPNLG SVYDQREVET
610 620 630 640 650
VLKLGLLCSH SDPQVRPTMR QVLQYLRGDA TLPDLSPLDF RGSGKMLGMN
660 670
HRFSESCTFS SGSSIAYSIV SGGR
Length:674
Mass (Da):75,923
Last modified:November 1, 1998 - v1
Checksum:i757FF9AFCF5A774D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF069298 Genomic DNA. Translation: AAC19286.1.
AL161494 Genomic DNA. Translation: CAB80734.1.
CP002687 Genomic DNA. Translation: AEE82167.1.
AY094440 mRNA. Translation: AAM19812.1.
AY094476 mRNA. Translation: AAM19843.1.
PIRiT01309.
RefSeqiNP_567233.1. NM_116474.4.
UniGeneiAt.34304.

Genome annotation databases

EnsemblPlantsiAT4G02410.1; AT4G02410.1; AT4G02410.
GeneIDi828032.
GrameneiAT4G02410.1; AT4G02410.1; AT4G02410.
KEGGiath:AT4G02410.

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF069298 Genomic DNA. Translation: AAC19286.1.
AL161494 Genomic DNA. Translation: CAB80734.1.
CP002687 Genomic DNA. Translation: AEE82167.1.
AY094440 mRNA. Translation: AAM19812.1.
AY094476 mRNA. Translation: AAM19843.1.
PIRiT01309.
RefSeqiNP_567233.1. NM_116474.4.
UniGeneiAt.34304.

3D structure databases

ProteinModelPortaliO81292.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO81292. 8 interactors.
STRINGi3702.AT4G02410.1.

Proteomic databases

PaxDbiO81292.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G02410.1; AT4G02410.1; AT4G02410.
GeneIDi828032.
GrameneiAT4G02410.1; AT4G02410.1; AT4G02410.
KEGGiath:AT4G02410.

Organism-specific databases

TAIRiAT4G02410.

Phylogenomic databases

eggNOGiENOG410IEGM. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116555.
InParanoidiO81292.
OMAiGMATEIT.
OrthoDBiEOG0936040C.
PhylomeDBiO81292.

Miscellaneous databases

PROiO81292.

Gene expression databases

GenevisibleiO81292. AT.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR031049. LecRK.
IPR019825. Lectin_legB_Mn/Ca_BS.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PANTHERiPTHR27007:SF13. PTHR27007:SF13. 1 hit.
PfamiPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00307. LECTIN_LEGUME_BETA. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLRK43_ARATH
AccessioniPrimary (citable) accession number: O81292
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 135 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.