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O81291 (LRK44_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 108. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
L-type lectin-domain containing receptor kinase IV.4

Short name=LecRK-IV.4
EC=2.7.11.1
Gene names
Name:LECRK44
Ordered Locus Names:At4g02420
ORF Names:T14P8.4
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length669 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Subcellular location

Cell membrane; Single-pass type I membrane protein By similarity.

Sequence similarities

In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

In the N-terminal section; belongs to the leguminous lectin family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 669646L-type lectin-domain containing receptor kinase IV.4
PRO_0000403088

Regions

Topological domain24 – 294271Extracellular Potential
Transmembrane295 – 31521Helical; Potential
Topological domain316 – 669354Cytoplasmic Potential
Domain350 – 627278Protein kinase
Nucleotide binding356 – 3649ATP By similarity
Region26 – 260235Legume-lectin like

Sites

Active site4751Proton acceptor By similarity
Binding site3791ATP By similarity

Amino acid modifications

Glycosylation581N-linked (GlcNAc...) Potential
Glycosylation801N-linked (GlcNAc...) Potential
Glycosylation1271N-linked (GlcNAc...) Potential
Glycosylation1521N-linked (GlcNAc...) Potential
Glycosylation1851N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
O81291 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 522142734DFAE0EB

FASTA66975,399
        10         20         30         40         50         60 
MFFIKLFTIF FLSFFWQSLK SSSQIIDFTY NGFRPPPTDI SILGIATITP NGLLKLTNTT 

        70         80         90        100        110        120 
MQSTGHAFYT KPIRFKDSPN GTVSSFSTTF VFAIHSQIPI AHGMAFVIAP NPRLPFGSPL 

       130        140        150        160        170        180 
QYLGLFNVTN NGNVRNHVFA VELDTIMNIE FNDTNNNHVG IDINSLNSVK SSPAGYWDEN 

       190        200        210        220        230        240 
DQFHNLTLIS SKRMQVWVDF DGPTHLIDVT MAPFGEVKPR KPLVSIVRDL SSVLLQDMFV 

       250        260        270        280        290        300 
GFSSATGNIV SEIFVLGWSF GVNGEAQPLA LSKLPRLPVW DLKPTRVYRF YKNWVPLISL 

       310        320        330        340        350        360 
LLIPFLLIIF LVRFIMKRRR KFAEEVEDWE TEFGKNRLRF KDLYYATKGF KDKNILGSGG 

       370        380        390        400        410        420 
FGSVYKGIMP KTKKEIAVKR VSNESRQGLK EFVAEIVSIG QMSHRNLVPL VGYCRRRDEL 

       430        440        450        460        470        480 
LLVYDYMPNG SLDKYLYNSP EVTLDWKQRF KVINGVASAL FYLHEEWEQV VIHRDVKASN 

       490        500        510        520        530        540 
VLLDAELNGR LGDFGLAQLC DHGSDPQTTR VVGTWGYLAP DHIRTGRATT TTDVFAFGVL 

       550        560        570        580        590        600 
LLEVACGRRP IEINNQSGER VVLVDWVFRF WMEANILDAK DPNLGSEYDQ KEVEMVLKLG 

       610        620        630        640        650        660 
LLCSHSDPLA RPTMRQVLQY LRGDAMLPDL SPLDLRGSGI MLGTHNGSNE SGMFTSGSSV 


AYSLLSSGR 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B. expand/collapse author list , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Lectin receptor kinases in plants."
Barre A., Herve C., Lescure B., Rouge P.
Crit. Rev. Plant Sci. 21:379-399(2002)
Cited for: GENE FAMILY.
[4]"Arabidopsis L-type lectin receptor kinases: phylogeny, classification, and expression profiles."
Bouwmeester K., Govers F.
J. Exp. Bot. 60:4383-4396(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF069298 Genomic DNA. Translation: AAC19274.1.
AL161494 Genomic DNA. Translation: CAB80735.1.
CP002687 Genomic DNA. Translation: AEE82168.1.
PIRT01308.
RefSeqNP_567234.1. NM_116475.1.
UniGeneAt.65321.

3D structure databases

ProteinModelPortalO81291.
SMRO81291. Positions 15-261, 305-651.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PaxDbO81291.
PRIDEO81291.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT4G02420.1; AT4G02420.1; AT4G02420.
GeneID828035.
KEGGath:AT4G02420.

Organism-specific databases

GeneFarm171. 4.
TAIRAT4G02420.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000116555.
InParanoidO81291.
OMAWETAFGP.
PhylomeDBO81291.
ProtClustDBCLSN2683086.

Enzyme and pathway databases

BioCycARA:AT4G02420-MONOMER.

Gene expression databases

GenevestigatorO81291.

Family and domain databases

Gene3D2.60.120.200. 1 hit.
InterProIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR011009. Kinase-like_dom.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLRK44_ARATH
AccessionPrimary (citable) accession number: O81291
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: November 1, 1998
Last modified: March 19, 2014
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names