Reviewed, UniProtKB/Swiss-Prot O81160 (SPE2_THECC)

Names and origin

Protein names

Recommended name:
    Arginine decarboxylase
      Short name=ARGDC
      Short name=ADC
    EC=4.1.1.19

Gene names

Name:

SPE2

Organism

Theobroma cacao (Cacao) (Cocoa)

Taxonomic identifier

3641 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Malvales › Malvaceae › Byttnerioideae › Theobroma

Protein attributes

Sequence length	406 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	L-arginine = agmatine + CO2.
Cofactor	Pyridoxal phosphate. Magnesium.
Pathway	Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.
Sequence similarities	Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Ontologies

Keywords
Biological process	Putrescine biosynthesis Spermidine biosynthesis
Ligand	Magnesium Pyridoxal phosphate
Molecular function	Decarboxylase Lyase
Gene Ontology (GO)
Biological process	arginine catabolic process Inferred from electronic annotation. Source: InterPro putrescine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW spermidine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	arginine decarboxylase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›406	›406	Arginine decarboxylase		PRO_0000149955
Regions
	Region	192 – 202	11	Substrate-binding By similarity
Amino acid modifications
	Modified residue	8	1	N6-(pyridoxal phosphate)lysine By similarity
Experimental info
	Non-terminal residue	1	1
	Non-terminal residue	406	1

Sequences

	Sequence		Length	Mass (Da)
	O81160-1 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: A736338EE8ADD4D6	FASTA	406	44,604
	10 20 30 40 50 60 YQGVYPVKSN QDRFVVEDIV KFGSSFRFGL EAGSKPELLL AMSCLCKGNP EALLVCNGFK 70 80 90 100 110 120 DAEYISLALL ARKLALKHVI VLEQEEEVDM VIDISQKLSV RPVIGVRAKL RTKHSGHFGS 130 140 150 160 170 180 TSGEKGKFGL TTTQVLRVVK KLQDSGMLDC LQLLHFHIGS QIPSTALLSD GVGEAAQIYS 190 200 210 220 230 240 ELVRLGARMK VVDFGGGLGI DYNGSKSGDS DLSVPYGLQE YAHVVNAIRF VCDRKSVKHP 250 260 270 280 290 300 VICSESGRAI VSHHSILIFE AICLTAPATH NEPINIPFIM EGLSEDACAD YWNLRDTAMR 310 320 330 340 350 360 TGDGAFWFYA DQWKQRCVEQ FKEGTLGIEQ LASVDGLCEW VLKAIGASDP VHTYNINLSV 370 380 390 400 FTSIPDLWGI DQLFPIVPIH KLDQRPGARG ILSDLTCDSD GKINKF

References

[1]	"Phylogenetic utility of the nuclear gene arginine decarboxylase: an example from Brassicaceae." Galloway G.L., Malmberg R.L., Price R.A. Mol. Biol. Evol. 15:1312-1320(1998) [PubMed: 9787437] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ADC.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF045666 Genomic DNA. Translation: AAC68511.1.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	4.1.1.19. 18928.
Family and domain databases
InterPro	IPR002985. Arg_decrbxlase. IPR000183. De-COase2. [Graphical view]
PANTHER	PTHR11482:SF3. Arg_decrbxlase. 1 hit.
Pfam	PF02784. Orn_Arg_deC_N. 1 hit. PF00278. Orn_DAP_Arg_deC. 1 hit. [Graphical view]
PRINTS	PR01180. ARGDCRBXLASE. PR01179. ODADCRBXLASE.
PROSITE	PS00878. ODR_DC_2_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SPE2_THECC

Accession

Primary (citable) accession number: O81160

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 21, 2001
Last sequence update:	November 1, 1998
Last modified:	July 28, 2009
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)