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Protein

Beta-galactosidase

Gene

TBG4

Organism
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei74 – 741GalactoseCombined sources
Binding sitei150 – 1501GalactoseCombined sources
Binding sitei199 – 1991GalactoseCombined sources
Binding sitei250 – 2501GalactoseCombined sources
Binding sitei312 – 3121GalactoseCombined sources
Binding sitei672 – 6721GalactoseCombined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationSAAS annotation, Hydrolase

Protein family/group databases

CAZyiGH35. Glycoside Hydrolase Family 35.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidaseUniRule annotation (EC:3.2.1.23UniRule annotation)
Gene namesi
Name:TBG4Imported
OrganismiSolanum lycopersicum (Tomato) (Lycopersicon esculentum)Imported
Taxonomic identifieri4081 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeSolanoideaeSolaneaeSolanumLycopersicon

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Chaini24 – 724701Beta-galactosidaseSequence analysisPRO_5004160165Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi229 ↔ 234Combined sources
Glycosylationi282 – 2821N-linked (GlcNAc...)Combined sourcesCAR_5005389742
Disulfide bondi370 ↔ 405Combined sources
Glycosylationi459 – 4591N-linked (GlcNAc...)Combined sourcesCAR_5005389743
Disulfide bondi664 ↔ 682Combined sources
Disulfide bondi667 ↔ 678Combined sources

Proteomic databases

PaxDbiO81100.

Interactioni

Protein-protein interaction databases

STRINGi4081.Solyc12g008840.1.1.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3W5FX-ray1.65A/B24-724[»]
3W5GX-ray3.00A/B24-724[»]
ProteinModelPortaliO81100.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini32 – 336305Glyco_hydro_35InterPro annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni117 – 1204Galactose bindingCombined sources
Regioni180 – 1812Galactose bindingCombined sources
Regioni233 – 2353Galactose bindingCombined sources

Sequence similaritiesi

Belongs to the glycosyl hydrolase 35 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0496. Eukaryota.
COG1874. LUCA.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR031330. Gly_Hdrlase_35_cat.
IPR019801. Glyco_hydro_35_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR001944. Glycoside_Hdrlase_35.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR23421. PTHR23421. 2 hits.
PfamiPF01301. Glyco_hydro_35. 1 hit.
[Graphical view]
PRINTSiPR00742. GLHYDRLASE35.
SUPFAMiSSF49785. SSF49785. 3 hits.
SSF51445. SSF51445. 1 hit.
PROSITEiPS01182. GLYCOSYL_HYDROL_F35. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O81100-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRTNVLLLL VICLLDFFSS VKASVSYDDR AIIINGKRKI LISGSIHYPR
60 70 80 90 100
STPQMWPDLI QKAKDGGLDV IETYVFWNGH EPSPGKYNFE GRYDLVRFIK
110 120 130 140 150
MVQRAGLYVN LRIGPYVCAE WNFGGFPVWL KYVPGMEFRT NNQPFKVAMQ
160 170 180 190 200
GFVQKIVNMM KSENLFESQG GPIIMAQIEN EYGPVEWEIG APGKAYTKWA
210 220 230 240 250
AQMAVGLKTG VPWIMCKQED APDPVIDTCN GFYCEGFRPN KPYKPKMWTE
260 270 280 290 300
VWTGWYTKFG GPIPQRPAED IAFSVARFVQ NNGSFFNYYM YHGGTNFGRT
310 320 330 340 350
SSGLFIATSY DYDAPLDEYG LLNEPKYGHL RDLHKAIKLS EPALVSSYAA
360 370 380 390 400
VTSLGSNQEA HVYRSKSGAC AAFLSNYDSR YSVKVTFQNR PYNLPPWSIS
410 420 430 440 450
ILPDCKTAVY NTAQVNSQSS SIKMTPAGGG LSWQSYNEET PTADDSDTLT
460 470 480 490 500
ANGLWEQKNV TRDSSDYLWY MTNVNIASNE GFLKNGKDPY LTVMSAGHVL
510 520 530 540 550
HVFVNGKLSG TVYGTLDNPK LTYSGNVKLR AGINKISLLS VSVGLPNVGV
560 570 580 590 600
HYDTWNAGVL GPVTLSGLNE GSRNLAKQKW SYKVGLKGES LSLHSLSGSS
610 620 630 640 650
SVEWVRGSLM AQKQPLTWYK ATFNAPGGND PLALDMASMG KGQIWINGEG
660 670 680 690 700
VGRHWPGYIA QGDCSKCSYA GTFNEKKCQT NCGQPSQRWY HVPRSWLKPS
710 720
GNLLVVFEEW GGNPTGISLV RRSR
Length:724
Mass (Da):80,514
Last modified:November 1, 1998 - v1
Checksum:i6F369499E25BDB2C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020390 mRNA. Translation: AAC25984.1.
PIRiT04340.
UniGeneiLes.4346.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020390 mRNA. Translation: AAC25984.1.
PIRiT04340.
UniGeneiLes.4346.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3W5FX-ray1.65A/B24-724[»]
3W5GX-ray3.00A/B24-724[»]
ProteinModelPortaliO81100.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4081.Solyc12g008840.1.1.

Protein family/group databases

CAZyiGH35. Glycoside Hydrolase Family 35.

Proteomic databases

PaxDbiO81100.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0496. Eukaryota.
COG1874. LUCA.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR031330. Gly_Hdrlase_35_cat.
IPR019801. Glyco_hydro_35_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR001944. Glycoside_Hdrlase_35.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR23421. PTHR23421. 2 hits.
PfamiPF01301. Glyco_hydro_35. 1 hit.
[Graphical view]
PRINTSiPR00742. GLHYDRLASE35.
SUPFAMiSSF49785. SSF49785. 3 hits.
SSF51445. SSF51445. 1 hit.
PROSITEiPS01182. GLYCOSYL_HYDROL_F35. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO81100_SOLLC
AccessioniPrimary (citable) accession number: O81100
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: May 11, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.