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Protein

ABC transporter G family member 32

Gene

ABCG32

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

May be a general defense protein (By similarity). Required for the formation of the cuticle layer of the cell wall (PubMed:21628525).By similarity1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi168 – 1758ATP 1PROSITE-ProRule annotation
Nucleotide bindingi863 – 8708ATP 2PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

  • cuticle development Source: TAIR
  • drug transmembrane transport Source: TAIR
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Protein family/group databases

TCDBi3.A.1.205.16. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter G family member 321 Publication
Short name:
ABC transporter ABCG.32
Short name:
AtABCG321 Publication
Alternative name(s):
Pleiotropic drug resistance protein 42 Publications
Protein PERMEABLE CUTICLE 11 Publication
Gene namesi
Name:ABCG321 Publication
Synonyms:PDR42 Publications, PEC11 Publication
Ordered Locus Names:At2g26910Imported
ORF Names:F12C20.5Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G26910.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei504 – 52421HelicalSequence analysisAdd
BLAST
Transmembranei544 – 56421HelicalSequence analysisAdd
BLAST
Transmembranei585 – 60521HelicalSequence analysisAdd
BLAST
Transmembranei623 – 64321HelicalSequence analysisAdd
BLAST
Transmembranei648 – 66821HelicalSequence analysisAdd
BLAST
Transmembranei674 – 69421HelicalSequence analysisAdd
BLAST
Transmembranei735 – 75521HelicalSequence analysisAdd
BLAST
Transmembranei1162 – 118221HelicalSequence analysisAdd
BLAST
Transmembranei1202 – 122221HelicalSequence analysisAdd
BLAST
Transmembranei1235 – 125521HelicalSequence analysisAdd
BLAST
Transmembranei1277 – 129721HelicalSequence analysisAdd
BLAST
Transmembranei1307 – 132721HelicalSequence analysisAdd
BLAST
Transmembranei1334 – 135421HelicalSequence analysisAdd
BLAST
Transmembranei1392 – 141221HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Chemical composition modifications and structural alterations of the cuticular layer of the cell wall leading to increased permeability of the cuticle, increased sensitivity to herbicide (glufosidate), increased cuticular transpiration and increased resistance to Botrytis cinerea.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 14201420ABC transporter G family member 32PRO_0000234631Add
BLAST

Proteomic databases

PaxDbiO81016.
PRIDEiO81016.

PTM databases

iPTMnetiO81016.

Expressioni

Tissue specificityi

Ubiquitous in aerial organs (PubMed:12430018, PubMed:21628525). Higher expression levels in young, expanding tissues than in older tissues. Detected in the epidermal layer (PubMed:21628525).2 Publications

Inductioni

Repressed by cycloheximide (CHX) and abscisic acid (ABA).1 Publication

Gene expression databases

GenevisibleiO81016. AT.

Interactioni

Protein-protein interaction databases

BioGridi2584. 1 interaction.
STRINGi3702.AT2G26910.1.

Structurei

3D structure databases

ProteinModelPortaliO81016.
SMRiO81016. Positions 144-416, 731-1071.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini135 – 408274ABC transporter 1PROSITE-ProRule annotationAdd
BLAST
Domaini486 – 699214ABC transmembrane type-2 1Add
BLAST
Domaini818 – 1070253ABC transporter 2PROSITE-ProRule annotationAdd
BLAST
Domaini1143 – 1357215ABC transmembrane type-2 2Add
BLAST

Sequence similaritiesi

Contains 2 ABC transporter domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0065. Eukaryota.
COG0842. LUCA.
HOGENOMiHOG000238051.
InParanoidiO81016.
OMAiPFRPYRY.
OrthoDBiEOG09360089.
PhylomeDBiO81016.

Family and domain databases

Gene3Di3.40.50.300. 3 hits.
InterProiIPR003593. AAA+_ATPase.
IPR013525. ABC_2_trans.
IPR029481. ABC_trans_N.
IPR003439. ABC_transporter-like.
IPR027417. P-loop_NTPase.
IPR013581. PDR_assoc.
[Graphical view]
PfamiPF01061. ABC2_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
PF14510. ABC_trans_N. 1 hit.
PF08370. PDR_assoc. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O81016-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWNSAENAFS RSTSFKDEIE DEEELRWAAL QRLPTYSRIR RGIFRDMVGE
60 70 80 90 100
PKEIQIGNLE ASEQRLLLDR LVNSVENDPE QFFARVRKRF DAVDLKFPKI
110 120 130 140 150
EVRFQNLMVE SFVHVGSRAL PTIPNFIINM AEGLLRNIHV IGGKRNKLTI
160 170 180 190 200
LDGISGVIRP SRLTLLLGPP SSGKTTLLLA LAGRLGTNLQ TSGKITYNGY
210 220 230 240 250
DLKEIIAPRT SAYVSQQDWH VAEMTVRQTL EFAGRCQGVG FKYDMLLELA
260 270 280 290 300
RREKLAGIVP DEDLDIFMKS LALGGMETSL VVEYVMKILG LDTCADTLVG
310 320 330 340 350
DEMIKGISGG QKKRLTTGEL LVGPARVLFM DEISNGLDSS TTHQIIMYMR
360 370 380 390 400
HSTHALEGTT VISLLQPSPE TYELFDDVIL MSEGQIIYQG PRDEVLDFFS
410 420 430 440 450
SLGFTCPDRK NVADFLQEVT SKKDQQQYWS VPFRPYRYVP PGKFAEAFRS
460 470 480 490 500
YPTGKKLAKK LEVPFDKRFN HSAALSTSQY GVKKSELLKI NFAWQKQLMK
510 520 530 540 550
QNAFIYVFKF VQLLLVALIT MTVFCRTTMH HNTIDDGNIY LGSLYFSMVI
560 570 580 590 600
ILFNGFTEVP MLVAKLPVLY KHRDLHFYPS WAYTLPSWLL SIPTSIIESA
610 620 630 640 650
TWVAVTYYTI GYDPLFSRFL QQFLLYFSLH QMSLGLFRVM GSLGRHMIVA
660 670 680 690 700
NTFGSFAMLV VMTLGGFIIS RDSIPSWWIW GYWISPLMYA QNAASVNEFL
710 720 730 740 750
GHNWQKTAGN HTSDSLGLAL LKERSLFSGN YWYWIGVAAL LGYTVLFNIL
760 770 780 790 800
FTLFLAHLNP WGKFQAVVSR EELDEREKKR KGDEFVVELR EYLQHSGSIH
810 820 830 840 850
GKYFKNRGMV LPFQPLSLSF SNINYYVDVP LGLKEQGILE DRLQLLVNIT
860 870 880 890 900
GAFRPGVLTA LVGVSGAGKT TLMDVLAGRK TGGTIEGDVY ISGFPKRQET
910 920 930 940 950
FARISGYCEQ NDVHSPCLTV VESLLFSACL RLPADIDSET QRAFVHEVME
960 970 980 990 1000
LVELTSLSGA LVGLPGVDGL STEQRKRLTI AVELVANPSI VFMDEPTSGL
1010 1020 1030 1040 1050
DARAAAIVMR TVRNIVNTGR TIVCTIHQPS IDIFESFDEL LFMKRGGELI
1060 1070 1080 1090 1100
YAGPLGQKSC ELIKYFESIE GVQKIKPGHN PAAWMLDVTA STEEHRLGVD
1110 1120 1130 1140 1150
FAEIYRNSNL CQRNKELIEV LSKPSNIAKE IEFPTRYSQS LYSQFVACLW
1160 1170 1180 1190 1200
KQNLSYWRNP QYTAVRFFYT VVISLMLGTI CWKFGSKRDT QQQLFNAMGS
1210 1220 1230 1240 1250
MYAAVLFIGI TNATAAQPVV SIERFVSYRE RAAGMYSALP FAFAQVFIEF
1260 1270 1280 1290 1300
PYVLAQSTIY STIFYAMAAF EWSAVKFLWY LFFMYFSIMY FTFYGMMTTA
1310 1320 1330 1340 1350
ITPNHNVASI IAAPFYMLWN LFSGFMIPYK RIPLWWRWYY WANPVAWTLY
1360 1370 1380 1390 1400
GLLVSQYGDD ERSVKLSDGI HQVMVKQLLE DVMGYKHDFL GVSAIMVVAF
1410 1420
CVFFSLVFAF AIKAFNFQRR
Length:1,420
Mass (Da):161,265
Last modified:November 1, 1998 - v1
Checksum:i9E192A9D5A46A601
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005168 Genomic DNA. Translation: AAC32236.1.
CP002685 Genomic DNA. Translation: AEC07906.1.
BX821941 mRNA. No translation available.
BK001003 Genomic DNA. Translation: DAA00872.1.
PIRiT02644.
RefSeqiNP_180259.1. NM_128248.1.
UniGeneiAt.12882.

Genome annotation databases

EnsemblPlantsiAT2G26910.1; AT2G26910.1; AT2G26910.
GeneIDi817232.
GrameneiAT2G26910.1; AT2G26910.1; AT2G26910.
KEGGiath:AT2G26910.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005168 Genomic DNA. Translation: AAC32236.1.
CP002685 Genomic DNA. Translation: AEC07906.1.
BX821941 mRNA. No translation available.
BK001003 Genomic DNA. Translation: DAA00872.1.
PIRiT02644.
RefSeqiNP_180259.1. NM_128248.1.
UniGeneiAt.12882.

3D structure databases

ProteinModelPortaliO81016.
SMRiO81016. Positions 144-416, 731-1071.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi2584. 1 interaction.
STRINGi3702.AT2G26910.1.

Protein family/group databases

TCDBi3.A.1.205.16. the atp-binding cassette (abc) superfamily.

PTM databases

iPTMnetiO81016.

Proteomic databases

PaxDbiO81016.
PRIDEiO81016.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G26910.1; AT2G26910.1; AT2G26910.
GeneIDi817232.
GrameneiAT2G26910.1; AT2G26910.1; AT2G26910.
KEGGiath:AT2G26910.

Organism-specific databases

TAIRiAT2G26910.

Phylogenomic databases

eggNOGiKOG0065. Eukaryota.
COG0842. LUCA.
HOGENOMiHOG000238051.
InParanoidiO81016.
OMAiPFRPYRY.
OrthoDBiEOG09360089.
PhylomeDBiO81016.

Miscellaneous databases

PROiO81016.

Gene expression databases

GenevisibleiO81016. AT.

Family and domain databases

Gene3Di3.40.50.300. 3 hits.
InterProiIPR003593. AAA+_ATPase.
IPR013525. ABC_2_trans.
IPR029481. ABC_trans_N.
IPR003439. ABC_transporter-like.
IPR027417. P-loop_NTPase.
IPR013581. PDR_assoc.
[Graphical view]
PfamiPF01061. ABC2_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
PF14510. ABC_trans_N. 1 hit.
PF08370. PDR_assoc. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAB32G_ARATH
AccessioniPrimary (citable) accession number: O81016
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: November 1, 1998
Last modified: September 7, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.