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Protein

L-type lectin-domain containing receptor kinase IV.1

Gene

LECRK41

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei376ATPPROSITE-ProRule annotation1
Active sitei472Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi353 – 361ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

  • response to salicylic acid Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Lectin, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
L-type lectin-domain containing receptor kinase IV.1 (EC:2.7.11.1)
Short name:
Arabidopsis thaliana lectin-receptor kinase e
Short name:
AthlecRK-e
Short name:
LecRK-IV.1
Alternative name(s):
Lectin Receptor Kinase 1
Gene namesi
Name:LECRK41
Synonyms:LECRKE, LRK1
Ordered Locus Names:At2g37710
ORF Names:F13M22.21
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G37710.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini23 – 291ExtracellularSequence analysisAdd BLAST269
Transmembranei292 – 312HelicalSequence analysisAdd BLAST21
Topological domaini313 – 675CytoplasmicSequence analysisAdd BLAST363

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000040308523 – 675L-type lectin-domain containing receptor kinase IV.1Add BLAST653

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi57N-linked (GlcNAc...)Sequence analysis1
Glycosylationi79N-linked (GlcNAc...)Sequence analysis1
Glycosylationi112N-linked (GlcNAc...)Sequence analysis1
Glycosylationi134N-linked (GlcNAc...)Sequence analysis1
Glycosylationi153N-linked (GlcNAc...)Sequence analysis1
Glycosylationi186N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiO80939.
PRIDEiO80939.

PTM databases

iPTMnetiO80939.

Expressioni

Gene expression databases

GenevisibleiO80939. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G37710.1.

Structurei

3D structure databases

ProteinModelPortaliO80939.
SMRiO80939.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini347 – 624Protein kinasePROSITE-ProRule annotationAdd BLAST278

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni25 – 261Legume-lectin likeAdd BLAST237

Sequence similaritiesi

In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Curated
In the N-terminal section; belongs to the leguminous lectin family.Curated
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IEGM. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116555.
InParanoidiO80939.
OMAiCDEKEVE.
OrthoDBiEOG0936040C.
PhylomeDBiO80939.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR031049. LecRK.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PANTHERiPTHR27007:SF13. PTHR27007:SF13. 1 hit.
PfamiPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O80939-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLKLLTIFF FFFFNLIFQS SSQSLNFAYN NGFNPPTDLS IQGITTVTPN
60 70 80 90 100
GLLKLTNTTV QKTGHAFYTK PIRFKDSPNG TVSSFSTSFV FAIHSQIAIL
110 120 130 140 150
SGHGIAFVVA PNASLPYGNP SQYIGLFNLA NNGNETNHVF AVELDTILST
160 170 180 190 200
EFNDTNDNHV GIDINSLKSV QSSPAGYWDE KGQFKNLTLI SRKPMQVWVD
210 220 230 240 250
YDGRTNKIDV TMAPFNEDKP TRPLVTAVRD LSSVLLQDMY VGFSSATGSV
260 270 280 290 300
LSEHYILGWS FGLNEKAPPL ALSRLPKLPR FEPKRISEFY KIGMPLISLF
310 320 330 340 350
LIFSFIFLVC YIVRRRRKFA EELEEWEKEF GKNRFRFKDL YYATKGFKEK
360 370 380 390 400
GLLGTGGFGS VYKGVMPGTK LEIAVKRVSH ESRQGMKEFV AEIVSIGRMS
410 420 430 440 450
HRNLVPLLGY CRRRGELLLV YDYMPNGSLD KYLYNTPEVT LNWKQRIKVI
460 470 480 490 500
LGVASGLFYL HEEWEQVVIH RDVKASNVLL DGELNGRLGD FGLARLYDHG
510 520 530 540 550
SDPQTTHVVG TLGYLAPEHT RTGRATMATD VFAFGAFLLE VACGRRPIEF
560 570 580 590 600
QQETDETFLL VDWVFGLWNK GDILAAKDPN MGSECDEKEV EMVLKLGLLC
610 620 630 640 650
SHSDPRARPS MRQVLHYLRG DAKLPELSPL DLSGSGMMFG VHDGFSELGM
660 670
SYSSSVFKGF TGGSSIADSQ LSGGR
Length:675
Mass (Da):75,541
Last modified:November 1, 1998 - v1
Checksum:iC3F2437E6ABA9967
GO

Sequence cautioni

The sequence CAA65153 differs from that shown. Reason: Frameshift at position 634.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti12Missing in CAA65153 (Ref. 1) Curated1
Sequence conflicti99I → S in CAA65153 (Ref. 1) Curated1
Sequence conflicti129 – 130LA → IT in CAA65153 (Ref. 1) Curated2
Sequence conflicti299 – 302LFLI → QFFF in CAA65153 (Ref. 1) Curated4
Sequence conflicti482G → R in CAA65153 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X95909 mRNA. Translation: CAA65153.1. Frameshift.
AC004684 Genomic DNA. Translation: AAC23641.1.
CP002685 Genomic DNA. Translation: AEC09438.1.
AY091070 mRNA. Translation: AAM13890.1.
PIRiT02537.
T50661.
RefSeqiNP_181307.1. NM_129327.4.
UniGeneiAt.12798.

Genome annotation databases

EnsemblPlantsiAT2G37710.1; AT2G37710.1; AT2G37710.
GeneIDi818348.
GrameneiAT2G37710.1; AT2G37710.1; AT2G37710.
KEGGiath:AT2G37710.

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X95909 mRNA. Translation: CAA65153.1. Frameshift.
AC004684 Genomic DNA. Translation: AAC23641.1.
CP002685 Genomic DNA. Translation: AEC09438.1.
AY091070 mRNA. Translation: AAM13890.1.
PIRiT02537.
T50661.
RefSeqiNP_181307.1. NM_129327.4.
UniGeneiAt.12798.

3D structure databases

ProteinModelPortaliO80939.
SMRiO80939.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G37710.1.

PTM databases

iPTMnetiO80939.

Proteomic databases

PaxDbiO80939.
PRIDEiO80939.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G37710.1; AT2G37710.1; AT2G37710.
GeneIDi818348.
GrameneiAT2G37710.1; AT2G37710.1; AT2G37710.
KEGGiath:AT2G37710.

Organism-specific databases

TAIRiAT2G37710.

Phylogenomic databases

eggNOGiENOG410IEGM. Eukaryota.
COG0515. LUCA.
HOGENOMiHOG000116555.
InParanoidiO80939.
OMAiCDEKEVE.
OrthoDBiEOG0936040C.
PhylomeDBiO80939.

Miscellaneous databases

PROiO80939.

Gene expression databases

GenevisibleiO80939. AT.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR031049. LecRK.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PANTHERiPTHR27007:SF13. PTHR27007:SF13. 1 hit.
PfamiPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLRK41_ARATH
AccessioniPrimary (citable) accession number: O80939
Secondary accession number(s): Q39139
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.