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O80939

- LRK41_ARATH

UniProt

O80939 - LRK41_ARATH

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Protein

L-type lectin-domain containing receptor kinase IV.1

Gene

LECRK41

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei376 – 3761ATPPROSITE-ProRule annotation
Active sitei472 – 4721Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi353 – 3619ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. carbohydrate binding Source: UniProtKB-KW
  3. protein serine/threonine kinase activity Source: UniProtKB-KW

GO - Biological processi

  1. response to salicylic acid Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Lectin, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT2G37710-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
L-type lectin-domain containing receptor kinase IV.1 (EC:2.7.11.1)
Short name:
Arabidopsis thaliana lectin-receptor kinase e
Short name:
AthlecRK-e
Short name:
LecRK-IV.1
Alternative name(s):
Lectin Receptor Kinase 1
Gene namesi
Name:LECRK41
Synonyms:LECRKE, LRK1
Ordered Locus Names:At2g37710
ORF Names:F13M22.21
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 2

Organism-specific databases

TAIRiAT2G37710.

Subcellular locationi

Cell membrane 1 Publication; Single-pass type I membrane protein 1 Publication

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence AnalysisAdd
BLAST
Chaini23 – 675653L-type lectin-domain containing receptor kinase IV.1PRO_0000403085Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi57 – 571N-linked (GlcNAc...)Sequence Analysis
Glycosylationi79 – 791N-linked (GlcNAc...)Sequence Analysis
Glycosylationi112 – 1121N-linked (GlcNAc...)Sequence Analysis
Glycosylationi134 – 1341N-linked (GlcNAc...)Sequence Analysis
Glycosylationi153 – 1531N-linked (GlcNAc...)Sequence Analysis
Glycosylationi186 – 1861N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiO80939.
PRIDEiO80939.

Expressioni

Gene expression databases

GenevestigatoriO80939.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G37710.1-P.

Structurei

3D structure databases

ProteinModelPortaliO80939.
SMRiO80939. Positions 34-281, 334-653.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini23 – 291269ExtracellularSequence AnalysisAdd
BLAST
Topological domaini313 – 675363CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei292 – 31221HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini347 – 624278Protein kinasePROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni25 – 261237Legume-lectin likeAdd
BLAST

Sequence similaritiesi

In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Curated
In the N-terminal section; belongs to the leguminous lectin family.Curated
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000116555.
InParanoidiO80939.
OMAiGHAFHPD.
PhylomeDBiO80939.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O80939 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFLKLLTIFF FFFFNLIFQS SSQSLNFAYN NGFNPPTDLS IQGITTVTPN
60 70 80 90 100
GLLKLTNTTV QKTGHAFYTK PIRFKDSPNG TVSSFSTSFV FAIHSQIAIL
110 120 130 140 150
SGHGIAFVVA PNASLPYGNP SQYIGLFNLA NNGNETNHVF AVELDTILST
160 170 180 190 200
EFNDTNDNHV GIDINSLKSV QSSPAGYWDE KGQFKNLTLI SRKPMQVWVD
210 220 230 240 250
YDGRTNKIDV TMAPFNEDKP TRPLVTAVRD LSSVLLQDMY VGFSSATGSV
260 270 280 290 300
LSEHYILGWS FGLNEKAPPL ALSRLPKLPR FEPKRISEFY KIGMPLISLF
310 320 330 340 350
LIFSFIFLVC YIVRRRRKFA EELEEWEKEF GKNRFRFKDL YYATKGFKEK
360 370 380 390 400
GLLGTGGFGS VYKGVMPGTK LEIAVKRVSH ESRQGMKEFV AEIVSIGRMS
410 420 430 440 450
HRNLVPLLGY CRRRGELLLV YDYMPNGSLD KYLYNTPEVT LNWKQRIKVI
460 470 480 490 500
LGVASGLFYL HEEWEQVVIH RDVKASNVLL DGELNGRLGD FGLARLYDHG
510 520 530 540 550
SDPQTTHVVG TLGYLAPEHT RTGRATMATD VFAFGAFLLE VACGRRPIEF
560 570 580 590 600
QQETDETFLL VDWVFGLWNK GDILAAKDPN MGSECDEKEV EMVLKLGLLC
610 620 630 640 650
SHSDPRARPS MRQVLHYLRG DAKLPELSPL DLSGSGMMFG VHDGFSELGM
660 670
SYSSSVFKGF TGGSSIADSQ LSGGR
Length:675
Mass (Da):75,541
Last modified:November 1, 1998 - v1
Checksum:iC3F2437E6ABA9967
GO

Sequence cautioni

The sequence CAA65153.1 differs from that shown. Reason: Frameshift at position 634.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti12 – 121Missing in CAA65153. 1 PublicationCurated
Sequence conflicti99 – 991I → S in CAA65153. 1 PublicationCurated
Sequence conflicti129 – 1302LA → IT in CAA65153. 1 PublicationCurated
Sequence conflicti299 – 3024LFLI → QFFF in CAA65153. 1 PublicationCurated
Sequence conflicti482 – 4821G → R in CAA65153. 1 PublicationCurated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X95909 mRNA. Translation: CAA65153.1. Frameshift.
AC004684 Genomic DNA. Translation: AAC23641.1.
CP002685 Genomic DNA. Translation: AEC09438.1.
AY091070 mRNA. Translation: AAM13890.1.
PIRiT02537.
T50661.
RefSeqiNP_181307.1. NM_129327.3.
UniGeneiAt.12798.

Genome annotation databases

EnsemblPlantsiAT2G37710.1; AT2G37710.1; AT2G37710.
GeneIDi818348.
KEGGiath:AT2G37710.

Cross-referencesi

Web resourcesi

PlantP kinase Classification PPC

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X95909 mRNA. Translation: CAA65153.1 . Frameshift.
AC004684 Genomic DNA. Translation: AAC23641.1 .
CP002685 Genomic DNA. Translation: AEC09438.1 .
AY091070 mRNA. Translation: AAM13890.1 .
PIRi T02537.
T50661.
RefSeqi NP_181307.1. NM_129327.3.
UniGenei At.12798.

3D structure databases

ProteinModelPortali O80939.
SMRi O80939. Positions 34-281, 334-653.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT2G37710.1-P.

Proteomic databases

PaxDbi O80939.
PRIDEi O80939.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT2G37710.1 ; AT2G37710.1 ; AT2G37710 .
GeneIDi 818348.
KEGGi ath:AT2G37710.

Organism-specific databases

GeneFarmi 83. 4.
TAIRi AT2G37710.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000116555.
InParanoidi O80939.
OMAi GHAFHPD.
PhylomeDBi O80939.

Enzyme and pathway databases

BioCyci ARA:AT2G37710-MONOMER.

Gene expression databases

Genevestigatori O80939.

Family and domain databases

Gene3Di 2.60.120.200. 1 hit.
InterProi IPR013320. ConA-like_dom.
IPR011009. Kinase-like_dom.
IPR001220. Legume_lectin_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00139. Lectin_legB. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A new class of receptor-like protein kinase gene from Arabidopsis thaliana possessing a domain with similarity to plant lectin genes."
    Swarup R., Dumas C., Cock J.M.
    Plant Gene Register PGR96-022
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Landsberg erecta.
    Tissue: Flower.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Characterization of the Arabidopsis lecRK-a genes: members of a superfamily encoding putative receptors with an extracellular domain homologous to legume lectins."
    Herve C., Serres J., Dabos P., Canut H., Barre A., Rouge P., Lescure B.
    Plant Mol. Biol. 39:671-682(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.
  6. Cited for: GENE FAMILY.
  7. "Arabidopsis plasma membrane proteomics identifies components of transport, signal transduction and membrane trafficking."
    Alexandersson E., Saalbach G., Larsson C., Kjellbom P.
    Plant Cell Physiol. 45:1543-1556(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Strain: cv. Columbia.
    Tissue: Leaf and Petiole.
  8. "Arabidopsis L-type lectin receptor kinases: phylogeny, classification, and expression profiles."
    Bouwmeester K., Govers F.
    J. Exp. Bot. 60:4383-4396(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiLRK41_ARATH
AccessioniPrimary (citable) accession number: O80939
Secondary accession number(s): Q39139
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: November 1, 1998
Last modified: October 29, 2014
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3