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O80939

- LRK41_ARATH

UniProt

O80939 - LRK41_ARATH

Protein

L-type lectin-domain containing receptor kinase IV.1

Gene

LECRK41

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 106 (01 Oct 2014)
      Sequence version 1 (01 Nov 1998)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei376 – 3761ATPPROSITE-ProRule annotation
    Active sitei472 – 4721Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi353 – 3619ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. carbohydrate binding Source: InterPro
    3. protein serine/threonine kinase activity Source: UniProtKB-KW

    GO - Biological processi

    1. response to salicylic acid Source: TAIR

    Keywords - Molecular functioni

    Kinase, Receptor, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Lectin, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciARA:AT2G37710-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    L-type lectin-domain containing receptor kinase IV.1 (EC:2.7.11.1)
    Short name:
    Arabidopsis thaliana lectin-receptor kinase e
    Short name:
    AthlecRK-e
    Short name:
    LecRK-IV.1
    Alternative name(s):
    Lectin Receptor Kinase 1
    Gene namesi
    Name:LECRK41
    Synonyms:LECRKE, LRK1
    Ordered Locus Names:At2g37710
    ORF Names:F13M22.21
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 2

    Organism-specific databases

    TAIRiAT2G37710.

    Subcellular locationi

    Cell membrane 1 Publication; Single-pass type I membrane protein 1 Publication

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: TAIR

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2222Sequence AnalysisAdd
    BLAST
    Chaini23 – 675653L-type lectin-domain containing receptor kinase IV.1PRO_0000403085Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi57 – 571N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi79 – 791N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi112 – 1121N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi134 – 1341N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi153 – 1531N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi186 – 1861N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiO80939.
    PRIDEiO80939.

    Expressioni

    Gene expression databases

    GenevestigatoriO80939.

    Interactioni

    Protein-protein interaction databases

    STRINGi3702.AT2G37710.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliO80939.
    SMRiO80939. Positions 34-281, 324-653.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini23 – 291269ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini313 – 675363CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei292 – 31221HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini347 – 624278Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni25 – 261237Legume-lectin likeAdd
    BLAST

    Sequence similaritiesi

    In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Curated
    In the N-terminal section; belongs to the leguminous lectin family.Curated
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000116555.
    InParanoidiO80939.
    OMAiGHAFHPD.
    PhylomeDBiO80939.

    Family and domain databases

    Gene3Di2.60.120.200. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR011009. Kinase-like_dom.
    IPR001220. Legume_lectin_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00139. Lectin_legB. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    O80939-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFLKLLTIFF FFFFNLIFQS SSQSLNFAYN NGFNPPTDLS IQGITTVTPN    50
    GLLKLTNTTV QKTGHAFYTK PIRFKDSPNG TVSSFSTSFV FAIHSQIAIL 100
    SGHGIAFVVA PNASLPYGNP SQYIGLFNLA NNGNETNHVF AVELDTILST 150
    EFNDTNDNHV GIDINSLKSV QSSPAGYWDE KGQFKNLTLI SRKPMQVWVD 200
    YDGRTNKIDV TMAPFNEDKP TRPLVTAVRD LSSVLLQDMY VGFSSATGSV 250
    LSEHYILGWS FGLNEKAPPL ALSRLPKLPR FEPKRISEFY KIGMPLISLF 300
    LIFSFIFLVC YIVRRRRKFA EELEEWEKEF GKNRFRFKDL YYATKGFKEK 350
    GLLGTGGFGS VYKGVMPGTK LEIAVKRVSH ESRQGMKEFV AEIVSIGRMS 400
    HRNLVPLLGY CRRRGELLLV YDYMPNGSLD KYLYNTPEVT LNWKQRIKVI 450
    LGVASGLFYL HEEWEQVVIH RDVKASNVLL DGELNGRLGD FGLARLYDHG 500
    SDPQTTHVVG TLGYLAPEHT RTGRATMATD VFAFGAFLLE VACGRRPIEF 550
    QQETDETFLL VDWVFGLWNK GDILAAKDPN MGSECDEKEV EMVLKLGLLC 600
    SHSDPRARPS MRQVLHYLRG DAKLPELSPL DLSGSGMMFG VHDGFSELGM 650
    SYSSSVFKGF TGGSSIADSQ LSGGR 675
    Length:675
    Mass (Da):75,541
    Last modified:November 1, 1998 - v1
    Checksum:iC3F2437E6ABA9967
    GO

    Sequence cautioni

    The sequence CAA65153.1 differs from that shown. Reason: Frameshift at position 634.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti12 – 121Missing in CAA65153. 1 PublicationCurated
    Sequence conflicti99 – 991I → S in CAA65153. 1 PublicationCurated
    Sequence conflicti129 – 1302LA → IT in CAA65153. 1 PublicationCurated
    Sequence conflicti299 – 3024LFLI → QFFF in CAA65153. 1 PublicationCurated
    Sequence conflicti482 – 4821G → R in CAA65153. 1 PublicationCurated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X95909 mRNA. Translation: CAA65153.1. Frameshift.
    AC004684 Genomic DNA. Translation: AAC23641.1.
    CP002685 Genomic DNA. Translation: AEC09438.1.
    AY091070 mRNA. Translation: AAM13890.1.
    PIRiT02537.
    T50661.
    RefSeqiNP_181307.1. NM_129327.3.
    UniGeneiAt.12798.

    Genome annotation databases

    EnsemblPlantsiAT2G37710.1; AT2G37710.1; AT2G37710.
    GeneIDi818348.
    KEGGiath:AT2G37710.

    Cross-referencesi

    Web resourcesi

    PlantP kinase Classification PPC

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X95909 mRNA. Translation: CAA65153.1 . Frameshift.
    AC004684 Genomic DNA. Translation: AAC23641.1 .
    CP002685 Genomic DNA. Translation: AEC09438.1 .
    AY091070 mRNA. Translation: AAM13890.1 .
    PIRi T02537.
    T50661.
    RefSeqi NP_181307.1. NM_129327.3.
    UniGenei At.12798.

    3D structure databases

    ProteinModelPortali O80939.
    SMRi O80939. Positions 34-281, 324-653.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT2G37710.1-P.

    Proteomic databases

    PaxDbi O80939.
    PRIDEi O80939.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT2G37710.1 ; AT2G37710.1 ; AT2G37710 .
    GeneIDi 818348.
    KEGGi ath:AT2G37710.

    Organism-specific databases

    GeneFarmi 83. 4.
    TAIRi AT2G37710.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000116555.
    InParanoidi O80939.
    OMAi GHAFHPD.
    PhylomeDBi O80939.

    Enzyme and pathway databases

    BioCyci ARA:AT2G37710-MONOMER.

    Gene expression databases

    Genevestigatori O80939.

    Family and domain databases

    Gene3Di 2.60.120.200. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR011009. Kinase-like_dom.
    IPR001220. Legume_lectin_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00139. Lectin_legB. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A new class of receptor-like protein kinase gene from Arabidopsis thaliana possessing a domain with similarity to plant lectin genes."
      Swarup R., Dumas C., Cock J.M.
      Plant Gene Register PGR96-022
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Landsberg erecta.
      Tissue: Flower.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    3. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    5. "Characterization of the Arabidopsis lecRK-a genes: members of a superfamily encoding putative receptors with an extracellular domain homologous to legume lectins."
      Herve C., Serres J., Dabos P., Canut H., Barre A., Rouge P., Lescure B.
      Plant Mol. Biol. 39:671-682(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY.
    6. Cited for: GENE FAMILY.
    7. "Arabidopsis plasma membrane proteomics identifies components of transport, signal transduction and membrane trafficking."
      Alexandersson E., Saalbach G., Larsson C., Kjellbom P.
      Plant Cell Physiol. 45:1543-1556(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
      Strain: cv. Columbia.
      Tissue: Leaf and Petiole.
    8. "Arabidopsis L-type lectin receptor kinases: phylogeny, classification, and expression profiles."
      Bouwmeester K., Govers F.
      J. Exp. Bot. 60:4383-4396(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiLRK41_ARATH
    AccessioniPrimary (citable) accession number: O80939
    Secondary accession number(s): Q39139
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 11, 2011
    Last sequence update: November 1, 1998
    Last modified: October 1, 2014
    This is version 106 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3