Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Dehydration-responsive element-binding protein 2E

Gene

DREB2E

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates abscisic acid-inducible transcription.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi69 – 13466AP2/ERFPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • abscisic acid-activated signaling pathway Source: UniProtKB-KW
  • cellular response to heat Source: TAIR
  • positive regulation of transcription, DNA-templated Source: TAIR
  • response to salt stress Source: TAIR
  • response to water deprivation Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Abscisic acid signaling pathway, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Dehydration-responsive element-binding protein 2E
Short name:
Protein DREB2E
Gene namesi
Name:DREB2E
Synonyms:ERF046
Ordered Locus Names:At2g38340
ORF Names:T19C21.17
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G38340.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 244244Dehydration-responsive element-binding protein 2EPRO_0000112538Add
BLAST

Proteomic databases

PaxDbiO80917.
PRIDEiO80917.

Expressioni

Inductioni

By abscisic acid (ABA) treatment.1 Publication

Gene expression databases

GenevisibleiO80917. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G38340.1.

Structurei

3D structure databases

ProteinModelPortaliO80917.
SMRiO80917. Positions 70-134.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi20 – 4627Nuclear localization signalSequence analysisAdd
BLAST

Sequence similaritiesi

Contains 1 AP2/ERF DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410JXR8. Eukaryota.
ENOG41103RG. LUCA.
HOGENOMiHOG000112271.
InParanoidiO80917.
OMAiPENPVCR.
PhylomeDBiO80917.

Family and domain databases

Gene3Di3.30.730.10. 1 hit.
InterProiIPR001471. AP2/ERF_dom.
IPR016177. DNA-bd_dom.
[Graphical view]
PfamiPF00847. AP2. 1 hit.
[Graphical view]
PRINTSiPR00367. ETHRSPELEMNT.
SMARTiSM00380. AP2. 1 hit.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS51032. AP2_ERF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O80917-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKEDNGSKQ SSSASVVSSR RRRRVVEPVE ATLQRWEEEG LARARRVQAK
60 70 80 90 100
GSKKGCMRGK GGPENPVCRF RGVRQRVWGK WVAEIREPVS HRGANSSRSK
110 120 130 140 150
RLWLGTFATA AEAALAYDRA ASVMYGPYAR LNFPEDLGGG RKKDEEAESS
160 170 180 190 200
GGYWLETNKA GNGVIETEGG KDYVVYNEDA IELGHDKTQN PMTDNEIVNP
210 220 230 240
AVKSEEGYSY DRFKLDNGLL YNEPQSSSYH QGGGFDSYFE YFRF
Length:244
Mass (Da):27,370
Last modified:November 1, 1998 - v1
Checksum:iB5029169499C138F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004683 Genomic DNA. Translation: AAC28770.1.
CP002685 Genomic DNA. Translation: AEC09525.1.
AY072421 mRNA. Translation: AAL62413.1.
BT006276 mRNA. Translation: AAP13384.1.
PIRiT02511.
RefSeqiNP_181368.1. NM_129390.2.
UniGeneiAt.37311.
At.74107.

Genome annotation databases

EnsemblPlantsiAT2G38340.1; AT2G38340.1; AT2G38340.
GeneIDi818414.
GrameneiAT2G38340.1; AT2G38340.1; AT2G38340.
KEGGiath:AT2G38340.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004683 Genomic DNA. Translation: AAC28770.1.
CP002685 Genomic DNA. Translation: AEC09525.1.
AY072421 mRNA. Translation: AAL62413.1.
BT006276 mRNA. Translation: AAP13384.1.
PIRiT02511.
RefSeqiNP_181368.1. NM_129390.2.
UniGeneiAt.37311.
At.74107.

3D structure databases

ProteinModelPortaliO80917.
SMRiO80917. Positions 70-134.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G38340.1.

Proteomic databases

PaxDbiO80917.
PRIDEiO80917.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G38340.1; AT2G38340.1; AT2G38340.
GeneIDi818414.
GrameneiAT2G38340.1; AT2G38340.1; AT2G38340.
KEGGiath:AT2G38340.

Organism-specific databases

TAIRiAT2G38340.

Phylogenomic databases

eggNOGiENOG410JXR8. Eukaryota.
ENOG41103RG. LUCA.
HOGENOMiHOG000112271.
InParanoidiO80917.
OMAiPENPVCR.
PhylomeDBiO80917.

Miscellaneous databases

PROiO80917.

Gene expression databases

GenevisibleiO80917. AT.

Family and domain databases

Gene3Di3.30.730.10. 1 hit.
InterProiIPR001471. AP2/ERF_dom.
IPR016177. DNA-bd_dom.
[Graphical view]
PfamiPF00847. AP2. 1 hit.
[Graphical view]
PRINTSiPR00367. ETHRSPELEMNT.
SMARTiSM00380. AP2. 1 hit.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS51032. AP2_ERF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "DNA-binding specificity of the ERF/AP2 domain of Arabidopsis DREBs, transcription factors involved in dehydration- and cold-inducible gene expression."
    Sakuma Y., Liu Q., Dubouzet J.G., Abe H., Shinozaki K., Yamaguchi-Shinozaki K.
    Biochem. Biophys. Res. Commun. 290:998-1009(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, FUNCTION, INDUCTION.
  5. "Genome-wide analysis of the ERF gene family in Arabidopsis and rice."
    Nakano T., Suzuki K., Fujimura T., Shinshi H.
    Plant Physiol. 140:411-432(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiDRE2E_ARATH
AccessioniPrimary (citable) accession number: O80917
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: November 1, 1998
Last modified: February 17, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.