Peroxidase 23 precursor - Arabidopsis thaliana (Mouse-ear cress)

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Reviewed, UniProtKB/Swiss-Prot O80912 (PER23_ARATH)

Last modified November 25, 2008. Version 72. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein names

Recommended name:
    Peroxidase 23
      Short name=Atperox P23
    EC=1.11.1.7
Alternative name(s):
    ATP34

Gene names

Name:	PER23
Synonyms:	P23
Ordered Locus Names:	At2g38390
ORF Names:	T19C21.12

Organism

Arabidopsis thaliana (Mouse-ear cress) [Complete proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

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Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

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General annotation (Comments)

Function	Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Catalytic activity	Donor + H(2)O(2) = oxidized donor + 2 H(2)O.
Cofactor	Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity. Binds 2 calcium ions per subunit By similarity.
Subcellular location	SecretedProbable. VacuoleProbable. Note= Carboxy-terminal extension appears to target the protein to vacuoles.
Induction	By methyl jasmonate, a plant defense-related signaling molecule.
Miscellaneous	There are 73 peroxidase genes in A.thaliana.
Sequence similarities	Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.

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Ontologies

Keywords
Biological process	Hydrogen peroxide
Cellular component	Secreted Vacuole
Domain	Signal
Ligand	Calcium Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
PTM	Glycoprotein Pyrrolidone carboxylic acid
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-KW vacuole Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	calcium ion binding Inferred from electronic annotation. Source: UniProtKB-KW electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW peroxidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

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Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Signal peptide

1 – 29

Potential

Chain

30 – 349

320

Peroxidase 23

PRO_0000023689

Sites

Active site

Proton acceptor By similarity

Metal binding

Calcium 1 By similarity

Metal binding

Calcium 1; via carbonyl oxygen By similarity

Metal binding

Calcium 1; via carbonyl oxygen By similarity

Metal binding

Calcium 1 By similarity

Metal binding

Calcium 1 By similarity

Metal binding

199

Iron (heme axial ligand) By similarity

Metal binding

200

Calcium 2 By similarity

Metal binding

251

Calcium 2 By similarity

Metal binding

254

Calcium 2 By similarity

Metal binding

259

Calcium 2 By similarity

Binding site

168

Substrate; via carbonyl oxygen By similarity

Site

Transition state stabilizer By similarity

Amino acid modifications

Modified residue

Pyrrolidone carboxylic acid By similarity

Glycosylation

N-linked (GlcNAc...) Potential

Glycosylation

217

N-linked (GlcNAc...) Potential

Glycosylation

243

N-linked (GlcNAc...) Potential

Disulfide bond

40 ↔ 120

By similarity

Disulfide bond

73 ↔ 78

By similarity

Disulfide bond

126 ↔ 329

By similarity

Disulfide bond

206 ↔ 238

By similarity

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Sequences

Sequence

Length

Mass (Da)

Tools

O80912-1 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 74A1C6F71A415169
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FASTA

349

38,100

        10         20         30         40         50         60 
MGFSSSLSCS AMGALIVGCL LLQASNSNAQ LRPDFYFRTC PPIFNIIGDT IVNELRTDPR 

        70         80         90        100        110        120 
IAASLLRLHF HDCFVRGCDA SILLDNSTSF RTEKDAAPNK NSVRGFDVID RMKAAIERAC 

       130        140        150        160        170        180 
PRTVSCADII TIASQISVLL SGGPWWPVPL GRRDSVEAFF ALANTALPSP FSTLTQLKTA 

       190        200        210        220        230        240 
FADVGLNRPS DLVALSGGHT FGKAQCQFVT PRLYNFNGTN RPDPSLNPTY LVELRRLCPQ 

       250        260        270        280        290        300 
NGNGTVLVNF DSVTPTTFDR QYYTNLLNGK GLIQSDQVLF STPGADTIPL VNQYSSNTFV 

       310        320        330        340 
FFGAFVDAMI RMGNLKPLTG TQGEIRQNCR VVNPRIRVVE NDDGVVSSI

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References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structural diversity and transcription of class III peroxidases from Arabidopsis thaliana." Welinder K.G., Justesen A.F., Kjaersgaard I.V.H., Jensen R.B., Rasmussen S.K., Jespersen H.M., Duroux L. Eur. J. Biochem. 269:6063-6081(2002) [PubMed: 12473102] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Columbia. Tissue: Root.
[2]	"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana." Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. Venter J.C. Nature 402:761-768(1999) [PubMed: 10617197] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[3]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
[4]	"Coordinated plant defense responses in Arabidopsis revealed by microarray analysis." Schenk P.M., Kazan K., Wilson I., Anderson J.P., Richmond T., Somerville S.C., Manners J.M. Proc. Natl. Acad. Sci. U.S.A. 97:11655-11660(2000) [PubMed: 11027363] [Abstract] Cited for: INDUCTION. Strain: cv. Columbia.
[5]	"Analysis and expression of the class III peroxidase large gene family in Arabidopsis thaliana." Tognolli M., Penel C., Greppin H., Simon P. Gene 288:129-138(2002) [PubMed: 12034502] [Abstract] Cited for: GENE FAMILY ORGANIZATION, NOMENCLATURE. Strain: cv. Columbia.

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Cross-references

Sequence databases
	AF452385 mRNA. Translation: AAL40849.1. AC004683 Genomic DNA. Translation: AAC28765.1. AY099555 mRNA. Translation: AAM20407.1. BT001238 mRNA. Translation: AAN65125.1.
PIR	T02506.
RefSeq	NP_181373.1.
UniGene	At.28466
3D structure databases
HSSP	HSSP built from PDB template 1GWU based on UniProtKB P00433.
ModBase	Search...
Protein family/group databases
PeroxiBase	116. AtPrx23.
Genome annotation databases
GeneID	818420.
GenomeReviews	Gene locus AT2G38390 in contig CT485783_GR.
KEGG	ath:AT2G38390.
NMPDR	fig\|3702.1.peg.10952.
Organism-specific databases
GeneFarm	1847. 61.
TAIR	At2g38390.
Gene expression databases
ArrayExpress	O80912.
GermOnline	AT2G38390. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR002016. Haem_peroxidase_pln/fun/bac. IPR000823. Peroxidase_pln. [Graphical view]
Pfam	PF00141. peroxidase. 1 hit. [Graphical view]
PRINTS	PR00458. PEROXIDASE. PR00461. PLPEROXIDASE.
PROSITE	PS00435. PEROXIDASE_1. 1 hit. PS00436. PEROXIDASE_2. 1 hit. PS50873. PEROXIDASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

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Entry information

Entry name

PER23_ARATH

Accession

Primary (citable) accession number: O80912

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 25, 2002
Last sequence update:	November 1, 1998
Last modified:	November 25, 2008
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)

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Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Keywords

Gene Ontology (GO)

Sequence annotation (Features)

Molecule processing

Sites

Amino acid modifications

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein family/group databases

Genome annotation databases

Organism-specific databases

Gene expression databases

Family and domain databases

Entry information

Relevant documents