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Protein

MADS-box transcription factor PHERES 1

Gene

PHE1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probable transcription factor involved in the development of gametophytes and seeds.1 Publication

Miscellaneous

The PHE1 locus is imprinted in gametophytes. Maternal inherited gene is repressed in female gametophyte, while the paternal inherited gene is expressed in the male gametophyte (pollen tube) and in fertilized seeds. The maternal repression is dependent on MEA, FIS2 and FIE proteins, which may modulate the methylation of the maternal locus, and repress its transcription.
This protein was called 'Pheres' in memory of one of the murdered sons of the mythological 'Medea', as PHERES1 is repressed by MEDEA.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
MADS-box transcription factor PHERES 1
Alternative name(s):
Agamous-like MADS-box protein AGL37
Gene namesi
Name:PHE1
Synonyms:AGL37
Ordered Locus Names:At1g65330
ORF Names:T8F5.11
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G65330
TAIRilocus:2206280 AT1G65330

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002331751 – 279MADS-box transcription factor PHERES 1Add BLAST279

Proteomic databases

PaxDbiO80805

Expressioni

Tissue specificityi

Male gametophyte, embryo and endosperm.2 Publications

Developmental stagei

Not present in female gametophyte before fertilization. Expressed in pollen tube and at the micropylar pole of pollinated seeds.1 Publication

Inductioni

Repressed by MEA, FIS2 and FIE in seeds, and by PKL after germination.2 Publications

Gene expression databases

ExpressionAtlasiO80805 baseline and differential
GenevisibleiO80805 AT

Interactioni

Subunit structurei

Interacts with AGL61/DIANA and AGL62.2 Publications

GO - Molecular functioni

Protein-protein interaction databases

BioGridi28062, 6 interactors
IntActiO80805, 8 interactors
STRINGi3702.AT1G65330.1

Structurei

3D structure databases

ProteinModelPortaliO80805
SMRiO80805
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 60MADS-boxPROSITE-ProRule annotationAdd BLAST60

Phylogenomic databases

eggNOGiKOG0014 Eukaryota
COG5068 LUCA
HOGENOMiHOG000006067
InParanoidiO80805
OrthoDBiEOG09360OKC
PhylomeDBiO80805

Family and domain databases

CDDicd00266 MADS_SRF_like, 1 hit
Gene3Di3.40.1810.10, 1 hit
InterProiView protein in InterPro
IPR033897 MADS_SRF-like
IPR002100 TF_MADSbox
IPR036879 TF_MADSbox_sf
PfamiView protein in Pfam
PF00319 SRF-TF, 1 hit
PRINTSiPR00404 MADSDOMAIN
SMARTiView protein in SMART
SM00432 MADS, 1 hit
SUPFAMiSSF55455 SSF55455, 1 hit
PROSITEiView protein in PROSITE
PS50066 MADS_BOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

O80805-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGKMKLSFI ENDSVRKTTF TKRKKGMLKK FNELVTLCGV DACAVIRSPY
60 70 80 90 100
NSIQEPWPSR EGVEEVMSKF MEFSVLDRTK KMVDQETFLR QRIAKETERL
110 120 130 140 150
QKLRDENRNS QIRDLMFGCL KGEVDVSHLH GRDLLDLNVF LNKYLNGVIR
160 170 180 190 200
RVEILKENGE SSSSVPPPIG VAPTVVDASV PIGFDGRMIQ DQNQNQQEPV
210 220 230 240 250
QFQYQALYDF YDQIPKKLHD FNMKMNIDPN QSMNLDLNDG EDEGIPCMDN
260 270
NNYHPEIDCL ATVTTAPTDV CAPNIINDL
Length:279
Mass (Da):31,953
Last modified:November 1, 1998 - v1
Checksum:iC054157870B8AE15
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti76L → I in strain: cv. Bla-1, cv. Bs-1, cv. Ita-0 and cv. Kas-1. 1 Publication1
Natural varianti128H → Q in strain: cv. Lisse-2. 1 Publication1
Natural varianti169I → T in strain: cv. Gr-3. 1 Publication1
Natural varianti230N → D in strain: cv. Co-1. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004512 Genomic DNA Translation: AAC27144.1
CP002684 Genomic DNA Translation: AEE34359.1
AF528574 Genomic DNA Translation: AAO43311.1
AF528575 Genomic DNA Translation: AAO43312.1
AF528576 Genomic DNA Translation: AAO43313.1
AF528577 Genomic DNA Translation: AAO43314.1
AF528578 Genomic DNA Translation: AAO43315.1
AF528579 Genomic DNA Translation: AAO43316.1
AF528580 Genomic DNA Translation: AAO43317.1
AF528581 Genomic DNA Translation: AAO43318.1
AF528582 Genomic DNA Translation: AAO43319.1
PIRiT02356
RefSeqiNP_176712.1, NM_105207.2
UniGeneiAt.64882

Genome annotation databases

EnsemblPlantsiAT1G65330.1; AT1G65330.1; AT1G65330
GeneIDi842841
GrameneiAT1G65330.1; AT1G65330.1; AT1G65330
KEGGiath:AT1G65330

Similar proteinsi

Entry informationi

Entry nameiPHE1_ARATH
AccessioniPrimary (citable) accession number: O80805
Secondary accession number(s): Q84JV4
, Q84JW5, Q84VN9, Q84VP0, Q84VP1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: November 1, 1998
Last modified: April 25, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names

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