O80738 (TPS10_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 10
EC=2.4.1.15

Alternative name(s):
Trehalose-6-phosphate synthase 10
Short name=AtTPS10

Gene names

Name:	TPS10
Synonyms:	TPS3
Ordered Locus Names:	At1g60140
ORF Names:	T13D8.4

Organism

Arabidopsis thaliana (Mouse-ear cress) [Reference proteome]

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	861 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.
Sequence similarities	In the N-terminal section; belongs to the glycosyltransferase 20 family. In the C-terminal section; belongs to the trehalose phosphatase family.

Ontologies

Keywords
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	trehalose biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	transferase activity, transferring glycosyl groups Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 861	861	Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 10		PRO_0000324831
Regions
	Region	59 – 546	488	Glycosyltransferase
Experimental info
	Sequence conflict	412	1	V → E in BAF01061. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	O80738 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: E00172C50669A7BA	FASTA	861	97,324
	10 20 30 40 50 60 MGSKSFGNLL DLASGDLLDI PQTPRYLPRV MTVPGIISDV DGYGISDGDS DVISLPCRER 70 80 90 100 110 120 KIIVANFLPL NGKKDSETGK WKFSLDNDSP LLHLKDGFSP ETEVIYVGSL KTHVDVSEQD 130 140 150 160 170 180 EVSHNLFEEF NCVATFLPQD VHKKFYLGFC KQQLWPLFHY MLPMCPDHGE RFDRGLWQAY 190 200 210 220 230 240 VSANKIFADK VMGVINLEED YIWIHDYHLM VLPTFLRRRF HRVKLGFFLH SPFPSSEIYR 250 260 270 280 290 300 TLPVREELLR GLLNCDLIGF HTFDYARHFL SCCCRMLGLE YESKRGHIAL DYLGRTVFLK 310 320 330 340 350 360 ILPIGIHMGR LESVLNLPAT AEKLKEIQEK YRGKKIILGV DDMDIFKGLS LKILAFEHLL 370 380 390 400 410 420 QQYPSMLGKI VLIQIVNPAR GSGKDVQEAR KETYDTVKRI NERYGSHDYE PVVLIDRPVP 430 440 450 460 470 480 RFEKSAYYAL AECCIVNAVR DGMNLVPYKY TVCRQGTPSM NKSLGVSDDL PRTSTLVLSE 490 500 510 520 530 540 FIGCSPSLSG AIRVNPWDVD AVADSLYSAI TMSDFEKQLR HKKHFHYIST HDVGYWARSF 550 560 570 580 590 600 SQDLERASRD HYSKRCWGVG WGLGFRLVAL SPNFRRLSIE QTVSAYRRSS KRAIFLDYDG 610 620 630 640 650 660 TLVPETSIVK DPSAEVISAL KALCSDPNNT IFIVSGRGKV SLSEWLAPCE NLGIAAEHGY 670 680 690 700 710 720 FTRWNKSSDW ETSGLSDDLE WKKVVEPIMR LYTETTDGSN IEAKESALVW HHQDADPDFG 730 740 750 760 770 780 SCQAKELLDH LETVLVNEPV IVNRGHQIVE VKPQGVSKGL VTGKILSRML EDGIAPDFVV 790 800 810 820 830 840 CIGDDRSDEE MFENISTTLS AQSSSMSTEI FACTVGRKPS KAKYFLDEVS DVVKLLQGLA 850 860 NTSSPKPRYP SHLRVSFESV V

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Isolation and characterization of Arabidopsis trehalose-6-phosphate synthase." Kim Y.S., Lee E.J., Kim J.S., Kim C.K., Lim D.H., Chung C.H. Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[3]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[4]	"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs." Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K. Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF155151 mRNA. Translation: AAO15312.1. AC004473 Genomic DNA. Translation: AAC24048.1. CP002684 Genomic DNA. Translation: AEE33662.1. AK229191 mRNA. Translation: BAF01061.1.
IPI	IPI00528357.
PIR	T02267.
RefSeq	NP_176221.1. NM_104705.3.
UniGene	At.27896.
3D structure databases
HSSP	HSSP built from PDB template 1UQT based on UniProtKB P31677.
ProteinModelPortal	O80738.
SMR	O80738. Positions 139-546.
ModBase	Search...
Protein-protein interaction databases
STRING	3702.AT1G60140.1-P.
Protein family/group databases
CAZy	GT20. Glycosyltransferase Family 20.
Proteomic databases
PaxDb	O80738.
PRIDE	O80738.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G60140.1; AT1G60140.1; AT1G60140.
GeneID	842309.
KEGG	ath:AT1G60140.
Organism-specific databases
TAIR	At1g60140.
Phylogenomic databases
eggNOG	COG0380.
HOGENOM	HOG000191476.
InParanoid	O80738.
KO	K16055.
OMA	SEWLAPC.
PhylomeDB	O80738.
ProtClustDB	CLSN2679729.
Gene expression databases
Genevestigator	O80738.
Family and domain databases
Gene3D	3.40.50.1000. 2 hits.
InterPro	IPR001830. Glyco_trans_20. IPR023214. HAD-like_dom. IPR006379. HAD-SF_hydro_IIB. IPR003337. Trehalose_PPase. [Graphical view]
Pfam	PF00982. Glyco_transf_20. 1 hit. PF02358. Trehalose_PPase. 1 hit. [Graphical view]
SUPFAM	SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01484. HAD-SF-IIB. 1 hit. TIGR00685. T6PP. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TPS10_ARATH

Accession

Primary (citable) accession number: O80738
Secondary accession number(s): Q0WP88

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	November 1, 1998
Last modified:	May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program