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Protein

Glutathione S-transferase TCHQD

Gene

TCHQD

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processDetoxification

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase TCHQD (EC:2.5.1.18)
Alternative name(s):
Protein tetrachlorohydroquinone dehalogenase-homolog
Gene namesi
Name:TCHQD
Ordered Locus Names:At1g77290
ORF Names:T14N5.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G77290
TAIRilocus:2195990 AT1G77290

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004135801 – 266Glutathione S-transferase TCHQDAdd BLAST266

Proteomic databases

PaxDbiO80662
PRIDEiO80662

PTM databases

iPTMnetiO80662

Expressioni

Gene expression databases

ExpressionAtlasiO80662 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G77290.1

Structurei

3D structure databases

ProteinModelPortaliO80662
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 80GST N-terminalAdd BLAST80
Domaini120 – 250GST C-terminalAdd BLAST131

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni9 – 10Glutathione bindingBy similarity2
Regioni38 – 39Glutathione bindingBy similarity2
Regioni51 – 52Glutathione bindingBy similarity2
Regioni64 – 65Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily.Curated

Phylogenomic databases

eggNOGiKOG4420 Eukaryota
ENOG410YE2J LUCA
HOGENOMiHOG000005689
InParanoidiO80662
KOiK22077
OMAiFHPYNFY
OrthoDBiEOG09360I5J
PhylomeDBiO80662

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF13417 GST_N_3, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

O80662-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLYHHPYSI DSQRVRLALE EKGIDYTSYH VNPITGKHMD PSFFRMNPNA
60 70 80 90 100
KLPVFRNGSH IILDTIEIIE YLERIAEVSS GIEDATFNRE VVEWMRKIRE
110 120 130 140 150
WESKLFTLAH IPDNRRLYVS KFLRMVVIAR MAESPDLASA YHRKLREAYD
160 170 180 190 200
TEDKLKDPGA LRRSKDHLLR LLDEVETKLE GTTYLAGNEF SMADVMLIPV
210 220 230 240 250
LARLSLLDLE EEYISSRKNL AEYWALVRRR PSYKKVIGRY FNGWRKYATL
260
VKTWMFVRVR SLLRKY
Length:266
Mass (Da):31,506
Last modified:November 1, 1998 - v1
Checksum:iD66A2B257ABC495D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004260 Genomic DNA Translation: AAC34354.1
CP002684 Genomic DNA Translation: AEE35958.1
CP002684 Genomic DNA Translation: AEE35959.1
CP002684 Genomic DNA Translation: ANM60330.1
AY064034 mRNA Translation: AAL36390.1
AK317233 mRNA Translation: BAH19914.1
BT015120 mRNA Translation: AAT71992.1
PIRiT00457
RefSeqiNP_001031292.1, NM_001036215.2
NP_001322626.1, NM_001334774.1
NP_177853.1, NM_106378.3
UniGeneiAt.27093

Genome annotation databases

EnsemblPlantsiAT1G77290.1; AT1G77290.1; AT1G77290
AT1G77290.2; AT1G77290.2; AT1G77290
AT1G77290.3; AT1G77290.3; AT1G77290
GeneIDi844065
GrameneiAT1G77290.1; AT1G77290.1; AT1G77290
AT1G77290.2; AT1G77290.2; AT1G77290
AT1G77290.3; AT1G77290.3; AT1G77290
KEGGiath:AT1G77290

Similar proteinsi

Entry informationi

Entry nameiTCHQD_ARATH
AccessioniPrimary (citable) accession number: O80662
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: November 1, 1998
Last modified: April 25, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health