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O80662

- TCHQD_ARATH

UniProt

O80662 - TCHQD_ARATH

Protein

Glutathione S-transferase TCHQD

Gene

TCHQD

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 105 (01 Oct 2014)
      Sequence version 1 (01 Nov 1998)
      Previous versions | rss
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    Functioni

    May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.By similarity

    Catalytic activityi

    RX + glutathione = HX + R-S-glutathione.

    GO - Molecular functioni

    1. glutathione transferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. response to toxic substance Source: UniProtKB-KW

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Detoxification

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutathione S-transferase TCHQD (EC:2.5.1.18)
    Alternative name(s):
    Protein tetrachlorohydroquinone dehalogenase-homolog
    Gene namesi
    Name:TCHQD
    Ordered Locus Names:At1g77290
    ORF Names:T14N5.14
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 1

    Organism-specific databases

    TAIRiAT1G77290.

    Subcellular locationi

    Cell membrane 1 Publication

    GO - Cellular componenti

    1. plasma membrane Source: TAIR

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 266266Glutathione S-transferase TCHQDPRO_0000413580Add
    BLAST

    Proteomic databases

    PaxDbiO80662.
    PRIDEiO80662.

    Expressioni

    Gene expression databases

    GenevestigatoriO80662.

    Interactioni

    Protein-protein interaction databases

    STRINGi3702.AT1G77290.2-P.

    Structurei

    3D structure databases

    ProteinModelPortaliO80662.
    SMRiO80662. Positions 1-238.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 8080GST N-terminalAdd
    BLAST
    Domaini120 – 250131GST C-terminalAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni9 – 102Glutathione bindingBy similarity
    Regioni38 – 392Glutathione bindingBy similarity
    Regioni51 – 522Glutathione bindingBy similarity
    Regioni64 – 652Glutathione bindingBy similarity

    Sequence similaritiesi

    Belongs to the GST superfamily.Curated
    Contains 1 GST C-terminal domain.Curated
    Contains 1 GST N-terminal domain.Curated

    Phylogenomic databases

    eggNOGiNOG307949.
    HOGENOMiHOG000005689.
    InParanoidiO80662.
    OMAiHPYSLDS.
    PhylomeDBiO80662.

    Family and domain databases

    Gene3Di1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProiIPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view]
    PfamiPF13417. GST_N_3. 1 hit.
    [Graphical view]
    SUPFAMiSSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEiPS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O80662-1 [UniParc]FASTAAdd to Basket

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    MQLYHHPYSI DSQRVRLALE EKGIDYTSYH VNPITGKHMD PSFFRMNPNA    50
    KLPVFRNGSH IILDTIEIIE YLERIAEVSS GIEDATFNRE VVEWMRKIRE 100
    WESKLFTLAH IPDNRRLYVS KFLRMVVIAR MAESPDLASA YHRKLREAYD 150
    TEDKLKDPGA LRRSKDHLLR LLDEVETKLE GTTYLAGNEF SMADVMLIPV 200
    LARLSLLDLE EEYISSRKNL AEYWALVRRR PSYKKVIGRY FNGWRKYATL 250
    VKTWMFVRVR SLLRKY 266
    Length:266
    Mass (Da):31,506
    Last modified:November 1, 1998 - v1
    Checksum:iD66A2B257ABC495D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004260 Genomic DNA. Translation: AAC34354.1.
    CP002684 Genomic DNA. Translation: AEE35958.1.
    CP002684 Genomic DNA. Translation: AEE35959.1.
    AY064034 mRNA. Translation: AAL36390.1.
    AK317233 mRNA. Translation: BAH19914.1.
    BT015120 mRNA. Translation: AAT71992.1.
    PIRiT00457.
    RefSeqiNP_001031292.1. NM_001036215.1.
    NP_177853.1. NM_106378.2.
    UniGeneiAt.27093.

    Genome annotation databases

    EnsemblPlantsiAT1G77290.1; AT1G77290.1; AT1G77290.
    AT1G77290.2; AT1G77290.2; AT1G77290.
    GeneIDi844065.
    KEGGiath:AT1G77290.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004260 Genomic DNA. Translation: AAC34354.1 .
    CP002684 Genomic DNA. Translation: AEE35958.1 .
    CP002684 Genomic DNA. Translation: AEE35959.1 .
    AY064034 mRNA. Translation: AAL36390.1 .
    AK317233 mRNA. Translation: BAH19914.1 .
    BT015120 mRNA. Translation: AAT71992.1 .
    PIRi T00457.
    RefSeqi NP_001031292.1. NM_001036215.1.
    NP_177853.1. NM_106378.2.
    UniGenei At.27093.

    3D structure databases

    ProteinModelPortali O80662.
    SMRi O80662. Positions 1-238.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT1G77290.2-P.

    Proteomic databases

    PaxDbi O80662.
    PRIDEi O80662.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT1G77290.1 ; AT1G77290.1 ; AT1G77290 .
    AT1G77290.2 ; AT1G77290.2 ; AT1G77290 .
    GeneIDi 844065.
    KEGGi ath:AT1G77290.

    Organism-specific databases

    TAIRi AT1G77290.

    Phylogenomic databases

    eggNOGi NOG307949.
    HOGENOMi HOG000005689.
    InParanoidi O80662.
    OMAi HPYSLDS.
    PhylomeDBi O80662.

    Miscellaneous databases

    PROi O80662.

    Gene expression databases

    Genevestigatori O80662.

    Family and domain databases

    Gene3Di 1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProi IPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view ]
    Pfami PF13417. GST_N_3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEi PS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
      Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
      , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
      Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
      Tissue: Rosette leaf.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Analysis of multiple occurrences of alternative splicing events in Arabidopsis thaliana using novel sequenced full-length cDNAs."
      Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M., Shinozaki K.
      DNA Res. 16:155-164(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    5. "Arabidopsis ORF clones."
      Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.
      Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    6. "Enzyme activities and subcellular localization of members of the Arabidopsis glutathione transferase superfamily."
      Dixon D.P., Hawkins T., Hussey P.J., Edwards R.
      J. Exp. Bot. 60:1207-1218(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION.

    Entry informationi

    Entry nameiTCHQD_ARATH
    AccessioniPrimary (citable) accession number: O80662
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 19, 2011
    Last sequence update: November 1, 1998
    Last modified: October 1, 2014
    This is version 105 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3