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Protein

Endoglucanase 15

Gene

At2g44570

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei414 – 4141PROSITE-ProRule annotation
Active sitei466 – 4661PROSITE-ProRule annotation
Active sitei475 – 4751PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cell wall biogenesis/degradation, Cellulose degradation, Polysaccharide degradation

Enzyme and pathway databases

BioCyciARA:AT2G44570-MONOMER.

Protein family/group databases

CAZyiGH9. Glycoside Hydrolase Family 9.

Names & Taxonomyi

Protein namesi
Recommended name:
Endoglucanase 15 (EC:3.2.1.4)
Alternative name(s):
Endo-1,4-beta glucanase 15
Gene namesi
Ordered Locus Names:At2g44570
ORF Names:F16B22.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G44570.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3030Sequence AnalysisAdd
BLAST
Chaini31 – 492462Endoglucanase 15PRO_0000249267Add
BLAST

Proteomic databases

PRIDEiO80497.

Structurei

3D structure databases

ProteinModelPortaliO80497.
SMRiO80497. Positions 33-491.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG05134.
HOGENOMiHOG000021033.
InParanoidiO80497.
OMAiRIDPDES.
PhylomeDBiO80497.

Family and domain databases

Gene3Di1.50.10.10. 1 hit.
InterProiIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR001701. Glyco_hydro_9.
IPR018221. Glyco_hydro_9_AS.
[Graphical view]
PfamiPF00759. Glyco_hydro_9. 1 hit.
[Graphical view]
SUPFAMiSSF48208. SSF48208. 1 hit.
PROSITEiPS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O80497-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSCISSQCFI TIKSICIVLL LSITCGAVSA NSNYGEALTK SLLYFEAQRS
60 70 80 90 100
GKLPLDQRVI WRGDSALRDG SDAHVDLTGG YYDAGDNMKF GFPLAFTTTM
110 120 130 140 150
LAWSSVEMES QLKAHQEHGN TLAALRWATD YLIKAHPEPN VLYGQVGDAN
160 170 180 190 200
LDHACWMRPE DMTTPRPSYR IDPQHPGADL AGETAAAMAA ASLAFAPSDS
210 220 230 240 250
AYAKTLISHA KELFEFAKDY PGVYHNSIPN AGGFYPSSGY EDELLWAAAW
260 270 280 290 300
LHRATGDQTY LDHLTQASNS GGARSVFAWD DKFLGAQVLV AKLVFEGKVK
310 320 330 340 350
NEGKMIEYKS MAEQFICNCA QKGFNNVKKT PGGLLWFLPW DNLQYTATAS
360 370 380 390 400
FALATYAKYL EAAQTSIQCP NGDVLQASDL LNLARAQVDY ILGSNPKKMS
410 420 430 440 450
YMVGYGTNYP KRPHHRGASI VSIKNDPKPV TCNGGFEAWY NNPKPNPNLL
460 470 480 490
VGAIVGGPDE YDAYGDERSD FQHGEPDTVT VAPLLGVLAA IA
Length:492
Mass (Da):53,591
Last modified:November 1, 1998 - v1
Checksum:i6FE816C89048D620
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003672 Genomic DNA. Translation: AAC27459.1.
CP002685 Genomic DNA. Translation: AEC10439.1.
PIRiT01584.
RefSeqiNP_181985.1. NM_130021.2.
UniGeneiAt.36741.

Genome annotation databases

EnsemblPlantsiAT2G44570.1; AT2G44570.1; AT2G44570.
GeneIDi819065.
KEGGiath:AT2G44570.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003672 Genomic DNA. Translation: AAC27459.1.
CP002685 Genomic DNA. Translation: AEC10439.1.
PIRiT01584.
RefSeqiNP_181985.1. NM_130021.2.
UniGeneiAt.36741.

3D structure databases

ProteinModelPortaliO80497.
SMRiO80497. Positions 33-491.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH9. Glycoside Hydrolase Family 9.

Proteomic databases

PRIDEiO80497.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G44570.1; AT2G44570.1; AT2G44570.
GeneIDi819065.
KEGGiath:AT2G44570.

Organism-specific databases

TAIRiAT2G44570.

Phylogenomic databases

eggNOGiNOG05134.
HOGENOMiHOG000021033.
InParanoidiO80497.
OMAiRIDPDES.
PhylomeDBiO80497.

Enzyme and pathway databases

BioCyciARA:AT2G44570-MONOMER.

Miscellaneous databases

PROiO80497.

Family and domain databases

Gene3Di1.50.10.10. 1 hit.
InterProiIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR001701. Glyco_hydro_9.
IPR018221. Glyco_hydro_9_AS.
[Graphical view]
PfamiPF00759. Glyco_hydro_9. 1 hit.
[Graphical view]
SUPFAMiSSF48208. SSF48208. 1 hit.
PROSITEiPS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Phylogenetic analysis of the plant endo-beta-1,4-glucanase gene family."
    Libertini E., Li Y., McQueen-Mason S.J.
    J. Mol. Evol. 58:506-515(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.

Entry informationi

Entry nameiGUN15_ARATH
AccessioniPrimary (citable) accession number: O80497
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: November 1, 1998
Last modified: June 24, 2015
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.