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O80497

- GUN15_ARATH

UniProt

O80497 - GUN15_ARATH

Protein

Endoglucanase 15

Gene

At2g44570

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (01 Nov 1998)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei414 – 4141PROSITE-ProRule annotation
    Active sitei466 – 4661PROSITE-ProRule annotation
    Active sitei475 – 4751PROSITE-ProRule annotation

    GO - Molecular functioni

    1. cellulase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cell wall biogenesis/degradation, Cellulose degradation, Polysaccharide degradation

    Enzyme and pathway databases

    BioCyciARA:AT2G44570-MONOMER.

    Protein family/group databases

    CAZyiGH9. Glycoside Hydrolase Family 9.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Endoglucanase 15 (EC:3.2.1.4)
    Alternative name(s):
    Endo-1,4-beta glucanase 15
    Gene namesi
    Ordered Locus Names:At2g44570
    ORF Names:F16B22.6
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 2

    Organism-specific databases

    TAIRiAT2G44570.

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 3030Sequence AnalysisAdd
    BLAST
    Chaini31 – 492462Endoglucanase 15PRO_0000249267Add
    BLAST

    Proteomic databases

    PRIDEiO80497.

    Expressioni

    Gene expression databases

    GenevestigatoriO80497.

    Interactioni

    Protein-protein interaction databases

    STRINGi3702.AT2G44570.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliO80497.
    SMRiO80497. Positions 33-491.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG05134.
    HOGENOMiHOG000021033.
    InParanoidiO80497.
    OMAiYESNIAN.
    PhylomeDBiO80497.

    Family and domain databases

    Gene3Di1.50.10.10. 1 hit.
    InterProiIPR008928. 6-hairpin_glycosidase-like.
    IPR012341. 6hp_glycosidase.
    IPR001701. Glyco_hydro_9.
    IPR018221. Glyco_hydro_9_AS.
    [Graphical view]
    PfamiPF00759. Glyco_hydro_9. 1 hit.
    [Graphical view]
    SUPFAMiSSF48208. SSF48208. 1 hit.
    PROSITEiPS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    O80497-1 [UniParc]FASTAAdd to Basket

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    MSCISSQCFI TIKSICIVLL LSITCGAVSA NSNYGEALTK SLLYFEAQRS    50
    GKLPLDQRVI WRGDSALRDG SDAHVDLTGG YYDAGDNMKF GFPLAFTTTM 100
    LAWSSVEMES QLKAHQEHGN TLAALRWATD YLIKAHPEPN VLYGQVGDAN 150
    LDHACWMRPE DMTTPRPSYR IDPQHPGADL AGETAAAMAA ASLAFAPSDS 200
    AYAKTLISHA KELFEFAKDY PGVYHNSIPN AGGFYPSSGY EDELLWAAAW 250
    LHRATGDQTY LDHLTQASNS GGARSVFAWD DKFLGAQVLV AKLVFEGKVK 300
    NEGKMIEYKS MAEQFICNCA QKGFNNVKKT PGGLLWFLPW DNLQYTATAS 350
    FALATYAKYL EAAQTSIQCP NGDVLQASDL LNLARAQVDY ILGSNPKKMS 400
    YMVGYGTNYP KRPHHRGASI VSIKNDPKPV TCNGGFEAWY NNPKPNPNLL 450
    VGAIVGGPDE YDAYGDERSD FQHGEPDTVT VAPLLGVLAA IA 492
    Length:492
    Mass (Da):53,591
    Last modified:November 1, 1998 - v1
    Checksum:i6FE816C89048D620
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC003672 Genomic DNA. Translation: AAC27459.1.
    CP002685 Genomic DNA. Translation: AEC10439.1.
    PIRiT01584.
    RefSeqiNP_181985.1. NM_130021.2.
    UniGeneiAt.36741.

    Genome annotation databases

    EnsemblPlantsiAT2G44570.1; AT2G44570.1; AT2G44570.
    GeneIDi819065.
    KEGGiath:AT2G44570.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC003672 Genomic DNA. Translation: AAC27459.1 .
    CP002685 Genomic DNA. Translation: AEC10439.1 .
    PIRi T01584.
    RefSeqi NP_181985.1. NM_130021.2.
    UniGenei At.36741.

    3D structure databases

    ProteinModelPortali O80497.
    SMRi O80497. Positions 33-491.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT2G44570.1-P.

    Protein family/group databases

    CAZyi GH9. Glycoside Hydrolase Family 9.

    Proteomic databases

    PRIDEi O80497.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT2G44570.1 ; AT2G44570.1 ; AT2G44570 .
    GeneIDi 819065.
    KEGGi ath:AT2G44570.

    Organism-specific databases

    TAIRi AT2G44570.

    Phylogenomic databases

    eggNOGi NOG05134.
    HOGENOMi HOG000021033.
    InParanoidi O80497.
    OMAi YESNIAN.
    PhylomeDBi O80497.

    Enzyme and pathway databases

    BioCyci ARA:AT2G44570-MONOMER.

    Gene expression databases

    Genevestigatori O80497.

    Family and domain databases

    Gene3Di 1.50.10.10. 1 hit.
    InterProi IPR008928. 6-hairpin_glycosidase-like.
    IPR012341. 6hp_glycosidase.
    IPR001701. Glyco_hydro_9.
    IPR018221. Glyco_hydro_9_AS.
    [Graphical view ]
    Pfami PF00759. Glyco_hydro_9. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48208. SSF48208. 1 hit.
    PROSITEi PS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Phylogenetic analysis of the plant endo-beta-1,4-glucanase gene family."
      Libertini E., Li Y., McQueen-Mason S.J.
      J. Mol. Evol. 58:506-515(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY.

    Entry informationi

    Entry nameiGUN15_ARATH
    AccessioniPrimary (citable) accession number: O80497
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 5, 2006
    Last sequence update: November 1, 1998
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3