Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

O80497 (GUN15_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endoglucanase 15

EC=3.2.1.4
Alternative name(s):
Endo-1,4-beta glucanase 15
Gene names
Ordered Locus Names:At2g44570
ORF Names:F16B22.6
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length492 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 9 (cellulase E) family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cell wall biogenesis/degradation
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncellulase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3030 Potential
Chain31 – 492462Endoglucanase 15
PRO_0000249267

Sites

Active site4141 By similarity
Active site4661 By similarity
Active site4751 By similarity

Sequences

Sequence LengthMass (Da)Tools
O80497 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 6FE816C89048D620

FASTA49253,591
        10         20         30         40         50         60 
MSCISSQCFI TIKSICIVLL LSITCGAVSA NSNYGEALTK SLLYFEAQRS GKLPLDQRVI 

        70         80         90        100        110        120 
WRGDSALRDG SDAHVDLTGG YYDAGDNMKF GFPLAFTTTM LAWSSVEMES QLKAHQEHGN 

       130        140        150        160        170        180 
TLAALRWATD YLIKAHPEPN VLYGQVGDAN LDHACWMRPE DMTTPRPSYR IDPQHPGADL 

       190        200        210        220        230        240 
AGETAAAMAA ASLAFAPSDS AYAKTLISHA KELFEFAKDY PGVYHNSIPN AGGFYPSSGY 

       250        260        270        280        290        300 
EDELLWAAAW LHRATGDQTY LDHLTQASNS GGARSVFAWD DKFLGAQVLV AKLVFEGKVK 

       310        320        330        340        350        360 
NEGKMIEYKS MAEQFICNCA QKGFNNVKKT PGGLLWFLPW DNLQYTATAS FALATYAKYL 

       370        380        390        400        410        420 
EAAQTSIQCP NGDVLQASDL LNLARAQVDY ILGSNPKKMS YMVGYGTNYP KRPHHRGASI 

       430        440        450        460        470        480 
VSIKNDPKPV TCNGGFEAWY NNPKPNPNLL VGAIVGGPDE YDAYGDERSD FQHGEPDTVT 

       490 
VAPLLGVLAA IA 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Phylogenetic analysis of the plant endo-beta-1,4-glucanase gene family."
Libertini E., Li Y., McQueen-Mason S.J.
J. Mol. Evol. 58:506-515(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC003672 Genomic DNA. Translation: AAC27459.1.
CP002685 Genomic DNA. Translation: AEC10439.1.
PIRT01584.
RefSeqNP_181985.1. NM_130021.2.
UniGeneAt.36741.

3D structure databases

ProteinModelPortalO80497.
SMRO80497. Positions 33-491.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT2G44570.1-P.

Protein family/group databases

CAZyGH9. Glycoside Hydrolase Family 9.

Proteomic databases

PRIDEO80497.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G44570.1; AT2G44570.1; AT2G44570.
GeneID819065.
KEGGath:AT2G44570.

Organism-specific databases

TAIRAT2G44570.

Phylogenomic databases

eggNOGNOG05134.
HOGENOMHOG000021033.
InParanoidO80497.
OMADWVENEV.
PhylomeDBO80497.
ProtClustDBPLN00119.

Enzyme and pathway databases

BioCycARA:AT2G44570-MONOMER.

Gene expression databases

GenevestigatorO80497.

Family and domain databases

Gene3D1.50.10.10. 1 hit.
InterProIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR001701. Glyco_hydro_9.
IPR018221. Glyco_hydro_9_AS.
[Graphical view]
PfamPF00759. Glyco_hydro_9. 1 hit.
[Graphical view]
SUPFAMSSF48208. SSF48208. 1 hit.
PROSITEPS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGUN15_ARATH
AccessionPrimary (citable) accession number: O80497
Entry history
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: November 1, 1998
Last modified: April 16, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names