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O80492

- P2C05_ARATH

UniProt

O80492 - P2C05_ARATH

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Protein

Probable protein phosphatase 2C 5

Gene

At1g09160

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi73 – 731Manganese 1By similarity
Metal bindingi73 – 731Manganese 2By similarity
Metal bindingi74 – 741Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi249 – 2491Manganese 2By similarity
Metal bindingi288 – 2881Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT1G09160-MONOMER.
ARA:GQT-100-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 5 (EC:3.1.3.16)
Short name:
AtPP2C05
Gene namesi
Ordered Locus Names:At1g09160
ORF Names:T12M4.15
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 1

Organism-specific databases

TAIRiAT1G09160.

Subcellular locationi

GO - Cellular componenti

  1. plasma membrane Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 428428Probable protein phosphatase 2C 5PRO_0000367937Add
BLAST

Proteomic databases

PaxDbiO80492.
PRIDEiO80492.

Expressioni

Gene expression databases

GenevestigatoriO80492.

Structurei

3D structure databases

ProteinModelPortaliO80492.
SMRiO80492. Positions 61-299.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini61 – 290230PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000240114.
InParanoidiO80492.
OMAiNKGTNKL.
PhylomeDBiO80492.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.

Sequencei

Sequence statusi: Complete.

O80492-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVSKASRTQ HSLVPLATLI GRELRSEKVE KPFVKYGQAA LAKKGEDYFL
60 70 80 90 100
IKTDCERVPG DPSSAFSVFG IFDGHNGNSA AIYTKEHLLE NVVSAIPQGA
110 120 130 140 150
SRDEWLQALP RALVAGFVKT DIEFQQKGET SGTTVTFVII DGWTITVASV
160 170 180 190 200
GDSRCILDTQ GGVVSLLTVD HRLEENVEER ERITASGGEV GRLNVFGGNE
210 220 230 240 250
VGPLRCWPGG LCLSRSIGDT DVGEFIVPIP HVKQVKLPDA GGRLIIASDG
260 270 280 290 300
IWDILSSDVA AKACRGLSAD LAAKLVVKEA LRTKGLKDDT TCVVVDIVPS
310 320 330 340 350
GHLSLAPAPM KKQNPFTSFL SRKNHMDTNN KNGNKLSAVG VVEELFEEGS
360 370 380 390 400
AVLADRLGKD LLSNTETGLL KCAVCQIDES PSEDLSSNGG SIISSASKRW
410 420
EGPFLCTICK KKKDAMEGKR PSKGSVTT
Length:428
Mass (Da):45,780
Last modified:November 1, 1998 - v1
Checksum:i63E584318E44B831
GO

Sequence cautioni

The sequence AAL31893.1 differs from that shown. Reason: Frameshift at position 355. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003114 Genomic DNA. Translation: AAC24088.1.
CP002684 Genomic DNA. Translation: AEE28405.1.
CP002684 Genomic DNA. Translation: AEE28406.1.
AF419561 mRNA. Translation: AAL31893.1. Frameshift.
BT029756 mRNA. Translation: ABM06026.1.
AK316880 mRNA. Translation: BAH19588.1.
PIRiA86224.
RefSeqiNP_172388.1. NM_100786.3.
NP_849621.1. NM_179290.2.
UniGeneiAt.27393.
At.65893.

Genome annotation databases

EnsemblPlantsiAT1G09160.1; AT1G09160.1; AT1G09160.
AT1G09160.2; AT1G09160.2; AT1G09160.
GeneIDi837436.
KEGGiath:AT1G09160.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003114 Genomic DNA. Translation: AAC24088.1 .
CP002684 Genomic DNA. Translation: AEE28405.1 .
CP002684 Genomic DNA. Translation: AEE28406.1 .
AF419561 mRNA. Translation: AAL31893.1 . Frameshift.
BT029756 mRNA. Translation: ABM06026.1 .
AK316880 mRNA. Translation: BAH19588.1 .
PIRi A86224.
RefSeqi NP_172388.1. NM_100786.3.
NP_849621.1. NM_179290.2.
UniGenei At.27393.
At.65893.

3D structure databases

ProteinModelPortali O80492.
SMRi O80492. Positions 61-299.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi O80492.
PRIDEi O80492.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT1G09160.1 ; AT1G09160.1 ; AT1G09160 .
AT1G09160.2 ; AT1G09160.2 ; AT1G09160 .
GeneIDi 837436.
KEGGi ath:AT1G09160.

Organism-specific databases

TAIRi AT1G09160.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000240114.
InParanoidi O80492.
OMAi NKGTNKL.
PhylomeDBi O80492.

Enzyme and pathway databases

BioCyci ARA:AT1G09160-MONOMER.
ARA:GQT-100-MONOMER.

Gene expression databases

Genevestigatori O80492.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Arabidopsis ORF clones."
    Bautista V.R., Kim C.J., Chen H., Wu S.Y., De Los Reyes C., Ecker J.R.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Analysis of multiple occurrences of alternative splicing events in Arabidopsis thaliana using novel sequenced full-length cDNAs."
    Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M., Shinozaki K.
    DNA Res. 16:155-164(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  6. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C05_ARATH
AccessioniPrimary (citable) accession number: O80492
Secondary accession number(s): Q8W588
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 1, 1998
Last modified: November 26, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3