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O80492 (P2C05_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable protein phosphatase 2C 5
Short name=AtPP2C05
EC=3.1.3.16
Gene names
Ordered Locus Names:At1g09160
ORF Names:T12M4.15
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length428 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

A phosphoprotein + H2O = a protein + phosphate.

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PP2C family.

Contains 1 PP2C-like domain.

Sequence caution

The sequence AAL31893.1 differs from that shown. Reason: Frameshift at position 355.

Ontologies

Keywords
   LigandMagnesium
Manganese
Metal-binding
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmetabolic process

Inferred from electronic annotation. Source: GOC

   Cellular_componentplasma membrane

Inferred from direct assay PubMed 17644812. Source: TAIR

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 428428Probable protein phosphatase 2C 5
PRO_0000367937

Regions

Domain61 – 290230PP2C-like

Sites

Metal binding731Manganese 1 By similarity
Metal binding731Manganese 2 By similarity
Metal binding741Manganese 1; via carbonyl oxygen By similarity
Metal binding2491Manganese 2 By similarity
Metal binding2881Manganese 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
O80492 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 63E584318E44B831

FASTA42845,780
        10         20         30         40         50         60 
MSVSKASRTQ HSLVPLATLI GRELRSEKVE KPFVKYGQAA LAKKGEDYFL IKTDCERVPG 

        70         80         90        100        110        120 
DPSSAFSVFG IFDGHNGNSA AIYTKEHLLE NVVSAIPQGA SRDEWLQALP RALVAGFVKT 

       130        140        150        160        170        180 
DIEFQQKGET SGTTVTFVII DGWTITVASV GDSRCILDTQ GGVVSLLTVD HRLEENVEER 

       190        200        210        220        230        240 
ERITASGGEV GRLNVFGGNE VGPLRCWPGG LCLSRSIGDT DVGEFIVPIP HVKQVKLPDA 

       250        260        270        280        290        300 
GGRLIIASDG IWDILSSDVA AKACRGLSAD LAAKLVVKEA LRTKGLKDDT TCVVVDIVPS 

       310        320        330        340        350        360 
GHLSLAPAPM KKQNPFTSFL SRKNHMDTNN KNGNKLSAVG VVEELFEEGS AVLADRLGKD 

       370        380        390        400        410        420 
LLSNTETGLL KCAVCQIDES PSEDLSSNGG SIISSASKRW EGPFLCTICK KKKDAMEGKR 


PSKGSVTT

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Arabidopsis ORF clones."
Bautista V.R., Kim C.J., Chen H., Wu S.Y., De Los Reyes C., Ecker J.R.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Analysis of multiple occurrences of alternative splicing events in Arabidopsis thaliana using novel sequenced full-length cDNAs."
Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M., Shinozaki K.
DNA Res. 16:155-164(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[6]"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC003114 Genomic DNA. Translation: AAC24088.1.
CP002684 Genomic DNA. Translation: AEE28405.1.
CP002684 Genomic DNA. Translation: AEE28406.1.
AF419561 mRNA. Translation: AAL31893.1. Frameshift.
BT029756 mRNA. Translation: ABM06026.1.
AK316880 mRNA. Translation: BAH19588.1.
IPIIPI00528808.
PIRA86224.
RefSeqNP_172388.1. NM_100786.3.
NP_849621.1. NM_179290.2.
UniGeneAt.27393.
At.65893.

3D structure databases

ProteinModelPortalO80492.
SMRO80492. Positions 61-299.
ModBaseSearch...

Proteomic databases

PaxDbO80492.
PRIDEO80492.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G09160.1; AT1G09160.1; AT1G09160.
AT1G09160.2; AT1G09160.2; AT1G09160.
GeneID837436.
KEGGath:AT1G09160.

Organism-specific databases

TAIRAt1g09160.

Phylogenomic databases

eggNOGCOG0631.
HOGENOMHOG000240114.
InParanoidO80492.
OMACGGQEVG.
PhylomeDBO80492.
ProtClustDBCLSN2679236.

Gene expression databases

GenevestigatorO80492.

Family and domain databases

Gene3D3.60.40.10. 1 hit.
InterProIPR001932. PP2C-like.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERPTHR13832. PTHR13832. 1 hit.
PfamPF00481. PP2C. 1 hit.
[Graphical view]
SMARTSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMSSF81606. PP2C-related. 1 hit.
PROSITEPS01032. PP2C. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameP2C05_ARATH
AccessionPrimary (citable) accession number: O80492
Secondary accession number(s): Q8W588
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 1, 1998
Last modified: May 1, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents