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Protein

Virion export protein

Gene

IV

Organism
Enterobacteria phage If1 (Bacteriophage If1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts in the assembly and extrusion of the bacteriophage by forming a channel across the host outer membrane. This channel is just large enough to allow a newly synthesized phage particle to pass through. Extrusion is a process of concomitant assembly and secretion and takes place at specific assembly sites where host inner and outer membranes are in close contacts (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Viral extrusion, Virus exit from host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Virion export protein
Alternative name(s):
Gene 4 protein
Short name:
G4P
Gene namesi
Name:IV
OrganismiEnterobacteria phage If1 (Bacteriophage If1)
Taxonomic identifieri10868 [NCBI]
Taxonomic lineageiVirusesssDNA virusesInoviridaeInovirus
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000001833 Componenti: Genome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei320 – 34021HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Host membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818Sequence analysisAdd
BLAST
Chaini19 – 429411Virion export proteinPRO_0000209451Add
BLAST

Interactioni

Subunit structurei

Homomultimer. The channel is composed of 14 G4P subunits that confer a barrel-like structure. Interacts with G1P; this interaction results in a complex that spans the inner an outer host membranes (By similarity).By similarity

Family & Domainsi

Sequence similaritiesi

Belongs to the inovirus G4P protein family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

KOiK02453.

Family and domain databases

InterProiIPR001775. GspD/PilQ.
IPR004846. T2SS/T3SS.
IPR004845. T2SS_GspD_CS.
[Graphical view]
PfamiPF00263. Secretin. 1 hit.
[Graphical view]
PRINTSiPR00811. BCTERIALGSPD.
PROSITEiPS00875. T2SP_D. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O80300-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKLLASLLC VLSFQSFAIP VELNNAPVRE FVSWYSKTTG KPVIISPDVK
60 70 80 90 100
GEITVYSADV TKDELPQFFT SVLRANGFDL SPGNPAVVQK FNRNTYEYSD
110 120 130 140 150
SFSEPVPASS YDGDVPPPTG DFFTKPEIRA NLITQTYPVN NVRAKDLAPV
160 170 180 190 200
IDIFLKGENI AGTKVYPLMG RIFLLVTASA SQHKELAAFF PSVDVPRTQV
210 220 230 240 250
LVESVIFETT ASDGFDFSFA AGDPSGSPVA GGINTDRLTS VLSSTGGSFG
260 270 280 290 300
IFNGNILGLS LKALETSSKS TLLSMPRILT MSGQPGTFTA GQNVPFVTGR
310 320 330 340 350
VTGEAANVNN PFQTIERHDV GISLKVVPVV TPGGLLIMDV STNADSISDS
360 370 380 390 400
QTASDIITNT RSISTTVQLK SGQTVLLGGM VDNRESDSDS SVPWVSKIPL
410 420
IGALFTSKSS NANKRTLYIL IRARVVNLL
Length:429
Mass (Da):45,863
Last modified:November 1, 1998 - v1
Checksum:i917DB3B75C3915C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U02303 Genomic DNA. Translation: AAC62158.1.
RefSeqiNP_047359.1. NC_001954.1.

Genome annotation databases

GeneIDi1261858.
KEGGivg:1261858.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U02303 Genomic DNA. Translation: AAC62158.1.
RefSeqiNP_047359.1. NC_001954.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1261858.
KEGGivg:1261858.

Phylogenomic databases

KOiK02453.

Family and domain databases

InterProiIPR001775. GspD/PilQ.
IPR004846. T2SS/T3SS.
IPR004845. T2SS_GspD_CS.
[Graphical view]
PfamiPF00263. Secretin. 1 hit.
[Graphical view]
PRINTSiPR00811. BCTERIALGSPD.
PROSITEiPS00875. T2SP_D. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "DNA sequence of the filamentous coliphage If1."
    Hill D.F., Hughes G., McNaughton J.C., Stockwell P.A., Petersen G.B.
    Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiG4P_BPIF1
AccessioniPrimary (citable) accession number: O80300
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1998
Last modified: May 11, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.