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O80292 (LYS_BPPS1) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lysozyme

EC=3.2.1.17
Alternative name(s):
Endolysin
Lysis protein
Muramidase
Protein gp19
Gene names
Name:19
OrganismBacteriophage PS119
Taxonomic identifier83128 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridae
Virus hostSalmonella typhimurium [TaxID: 90371]

Protein attributes

Sequence length167 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity By similarity.

Catalytic activity

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Sequence similarities

Belongs to the glycosyl hydrolase 24 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 167167Lysozyme
PRO_0000218105

Sites

Active site371Proton donor By similarity
Active site461Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
O80292 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: E1D72ACCA49E32FC

FASTA16718,232
        10         20         30         40         50         60 
MAMSPALRNS VMAAISGGAI AIASVLITGP GGNDGLEGVR YKPYKDVVGV LTVCYGHTGK 

        70         80         90        100        110        120 
DIMPGKTYTE AECKALLNKD LITVARQINP YIKVDIPETT RGALYSFVYN VGAGNFRTST 

       130        140        150        160 
LLRKINQGDI KGACDQLRRW TYAGGKQWKG LMTRREVERD VCLWGKQ 

« Hide

References

[1]"Lysis gene modules in the phage P22 gene pool."
Zimmer A., Schmieger H.
Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ011581 Genomic DNA. Translation: CAA09710.1.

3D structure databases

ProteinModelPortalO80292.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH24. Glycoside Hydrolase Family 24.

Proteomic databases

PRIDEO80292.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.530.40. 1 hit.
InterProIPR002196. Glyco_hydro_24.
IPR023346. Lysozyme-like_dom.
IPR023347. Lysozyme_dom.
[Graphical view]
PfamPF00959. Phage_lysozyme. 1 hit.
[Graphical view]
SUPFAMSSF53955. SSF53955. 1 hit.
ProtoNetSearch...

Entry information

Entry nameLYS_BPPS1
AccessionPrimary (citable) accession number: O80292
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1998
Last modified: October 16, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries