Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA polymerase processivity component

Gene

45

Organism
Enterobacteria phage RB69 (Bacteriophage RB69)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Replisome sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.1 Publication

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA replication, Viral DNA replication

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase processivity component
Alternative name(s):
DNA polymerase accessory protein 45
Gp45
Gene namesi
Name:45
OrganismiEnterobacteria phage RB69 (Bacteriophage RB69)
Taxonomic identifieri12353 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesMyoviridaeTevenvirinaeT4likevirus
Virus hostiEscherichia coli [TaxID: 562]
Proteomesi
  • UP000000876 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001492281 – 228DNA polymerase processivity componentAdd BLAST228

Interactioni

Subunit structurei

Homotrimer.

Structurei

Secondary structure

1228
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi5 – 15Combined sources11
Beta strandi21 – 23Combined sources3
Beta strandi25 – 32Combined sources8
Beta strandi36 – 48Combined sources13
Beta strandi52 – 55Combined sources4
Helixi57 – 64Combined sources8
Beta strandi72 – 75Combined sources4
Beta strandi79 – 84Combined sources6
Beta strandi86 – 92Combined sources7
Helixi97 – 99Combined sources3
Beta strandi113 – 118Combined sources6
Helixi120 – 132Combined sources13
Beta strandi137 – 143Combined sources7
Beta strandi146 – 152Combined sources7
Turni154 – 156Combined sources3
Beta strandi164 – 171Combined sources8
Beta strandi178 – 183Combined sources6
Helixi184 – 186Combined sources3
Beta strandi194 – 201Combined sources8
Beta strandi204 – 210Combined sources7
Beta strandi215 – 219Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1B77X-ray2.10A/B/C1-228[»]
1B8HX-ray3.00A/B/C1-228[»]
1QE4model-A/B/C1-228[»]
ProteinModelPortaliO80164.
SMRiO80164.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO80164.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK18943.

Family and domain databases

InterProiIPR004190. DNA_pol_proc_fac.
IPR015200. Gp45_slide_clamp_C.
[Graphical view]
PfamiPF02916. DNA_PPF. 1 hit.
PF09116. gp45-slide_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O80164-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLSKDTIAI LKNFASINSG ILLSQGKFIM TRAVNGTTYA EANISDEIDF
60 70 80 90 100
DVALYDLNSF LSILSLVSDD AEISMHTDGN IKIADTRSTV YWPAADKSTI
110 120 130 140 150
VFPNKPIQFP VASVITEIKA EDLQQLLRVS RGLQIDTIAI TNKDGKIVIN
160 170 180 190 200
GYNKVEDSGL TRPKYSLTLT DYDGSNNFNF VINMANMKIQ PGNYKVMLWG
210 220
AGDKVAAKFE SSQVSYVIAM EADSTHDF
Length:228
Mass (Da):25,111
Last modified:November 1, 1998 - v1
Checksum:i158C771A684E4666
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF039565 Genomic DNA. Translation: AAC39310.1.
AY303349 Genomic DNA. Translation: AAP75962.1.
RefSeqiNP_861750.1. NC_004928.1.

Genome annotation databases

GeneIDi1494176.
KEGGivg:1494176.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF039565 Genomic DNA. Translation: AAC39310.1.
AY303349 Genomic DNA. Translation: AAP75962.1.
RefSeqiNP_861750.1. NC_004928.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1B77X-ray2.10A/B/C1-228[»]
1B8HX-ray3.00A/B/C1-228[»]
1QE4model-A/B/C1-228[»]
ProteinModelPortaliO80164.
SMRiO80164.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1494176.
KEGGivg:1494176.

Phylogenomic databases

KOiK18943.

Miscellaneous databases

EvolutionaryTraceiO80164.

Family and domain databases

InterProiIPR004190. DNA_pol_proc_fac.
IPR015200. Gp45_slide_clamp_C.
[Graphical view]
PfamiPF02916. DNA_PPF. 1 hit.
PF09116. gp45-slide_C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDPA5_BPR69
AccessioniPrimary (citable) accession number: O80164
Secondary accession number(s): Q76XX6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.