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O79676 (COX3_PELSU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3
EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:MT-CO3
Synonyms:COIII, COXIII, MTCO3
Encoded onMitochondrion
OrganismPelomedusa subrufa (African side-necked turtle)
Taxonomic identifier44522 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Testudines › Pleurodira › Pelomedusidae › Pelomedusa

Protein attributes

Sequence length261 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentMembrane
Mitochondrion
Mitochondrion inner membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

mitochondrial inner membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 261261Cytochrome c oxidase subunit 3
PRO_0000183828

Regions

Transmembrane31 – 5121Helical; Potential
Transmembrane81 – 10121Helical; Potential
Transmembrane127 – 14721Helical; Potential
Transmembrane162 – 18221Helical; Potential
Transmembrane197 – 21721Helical; Potential
Transmembrane239 – 25921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
O79676 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: A09EEEB65C23C82C

FASTA26129,934
        10         20         30         40         50         60 
MTNQLHPFHM TNPSPWPLTG ATAALLMTSG LIMWFHYNSS QLIMLGLLIM LLTLTQWWRD 

        70         80         90        100        110        120 
IVRESTFQGH HTPSVQNNLR YGMILFITSE ILFFTGFFWA FYHSSLSPTA ELGNIWPPTG 

       130        140        150        160        170        180 
ITPLNPFEVP LLNTAVLLAS GVTITWAHHS LMEGNRPQTL QALTLTIILG TYFTILQAME 

       190        200        210        220        230        240 
YFEASFTIAD SIYGSTFFVA TGFHGLHVII GSTFLIVCLM RQLKYHFTSH HHFGFEAAAW 

       250        260 
YWHFVDVIWL FLYLSIYWWG S

« Hide

References

[1]"Complete mitochondrial genome suggests diapsid affinities of turtles."
Zardoya R., Meyer A.
Proc. Natl. Acad. Sci. U.S.A. 95:14226-14231(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF039066 Genomic DNA. Translation: AAD05056.1.
PIRT11107.
RefSeqNP_008438.1. NC_001947.1.

3D structure databases

ProteinModelPortalO79676.
SMRO79676. Positions 1-261.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID808279.

Organism-specific databases

CTD4514.

Phylogenomic databases

HOVERGENHBG016686.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. CytC_oxdse_III. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_PELSU
AccessionPrimary (citable) accession number: O79676
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1998
Last modified: April 3, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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