Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

ATP synthase subunit a

Gene

MT-ATP6

Organism
Pelomedusa subrufa (African side-necked turtle)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

ATP synthesis, Hydrogen ion transport, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit a
Alternative name(s):
F-ATPase protein 6
Gene namesi
Name:MT-ATP6
Synonyms:ATP6, ATPASE6, MTATP6
Encoded oniMitochondrion
OrganismiPelomedusa subrufa (African side-necked turtle)
Taxonomic identifieri44522 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaTestudinesPleurodiraPelomedusidaePelomedusa

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei13 – 3321HelicalSequence analysisAdd
BLAST
Transmembranei69 – 8921HelicalSequence analysisAdd
BLAST
Transmembranei98 – 11821HelicalSequence analysisAdd
BLAST
Transmembranei139 – 15921HelicalSequence analysisAdd
BLAST
Transmembranei194 – 21421HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CF(0), Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 228228ATP synthase subunit aPRO_0000082151Add
BLAST

Interactioni

Subunit structurei

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c.

Structurei

3D structure databases

ProteinModelPortaliO79675.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase A chain family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG016693.

Family and domain databases

Gene3Di1.20.120.220. 1 hit.
InterProiIPR000568. ATPase_F0-cplx_asu.
[Graphical view]
PANTHERiPTHR11410. PTHR11410. 1 hit.
PfamiPF00119. ATP-synt_A. 1 hit.
[Graphical view]
PRINTSiPR00123. ATPASEA.
SUPFAMiSSF81336. SSF81336. 1 hit.
TIGRFAMsiTIGR01131. ATP_synt_6_or_A. 1 hit.

Sequencei

Sequence statusi: Complete.

O79675-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLTLFDQFS SPNILAIPLM TISLLMLTII FPMKHNRLLT NRLLSIQSKM
60 70 80 90 100
IHIFTKQLML PIPKSGHHWA LILTSLMTLL LTSNLLGLLP YTFTPTTQLS
110 120 130 140 150
MNLGFALPMW LATLLIGLRN QPTMSLAHLL PEGTPTPLIP TLILIESISL
160 170 180 190 200
MIRPLALGVR ISANLTAGHL LMQLTSSATL SLSSMPTLSF MTAILLFLLT
210 220
ILEMAVAMIQ ALVFVLLLSL YLQENTHN
Length:228
Mass (Da):25,250
Last modified:November 1, 1998 - v1
Checksum:iD483209845A7DDEA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF039066 Genomic DNA. Translation: AAD05055.1.
PIRiT11106.
RefSeqiNP_008437.1. NC_001947.1.

Genome annotation databases

GeneIDi808286.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF039066 Genomic DNA. Translation: AAD05055.1.
PIRiT11106.
RefSeqiNP_008437.1. NC_001947.1.

3D structure databases

ProteinModelPortaliO79675.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi808286.

Organism-specific databases

CTDi4508.

Phylogenomic databases

HOVERGENiHBG016693.

Family and domain databases

Gene3Di1.20.120.220. 1 hit.
InterProiIPR000568. ATPase_F0-cplx_asu.
[Graphical view]
PANTHERiPTHR11410. PTHR11410. 1 hit.
PfamiPF00119. ATP-synt_A. 1 hit.
[Graphical view]
PRINTSiPR00123. ATPASEA.
SUPFAMiSSF81336. SSF81336. 1 hit.
TIGRFAMsiTIGR01131. ATP_synt_6_or_A. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiATP6_PELSU
AccessioniPrimary (citable) accession number: O79675
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1998
Last modified: February 4, 2015
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.